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European Radiology
Erschienen in:

18.03.2021 | Cardiac

Indication of the prognosis of pulmonary hypertension by using CMR function parameters

verfasst von: Wen Ren, Jing-Jing Guo, Fan Yang, Zhen-Wen Yang, Tie-Lian Yu, Yuan-Lin Deng, Zhang Zhang, Dong Li

Erschienen in: European Radiology | Ausgabe 9/2021

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Abstract

Objective

This study aimed to compare the cardiac function among different sub-types of pulmonary hypertension (PH) and to explore the independent predictors of major adverse cardiovascular events (MACE).

Methods

Eighty-seven PH patients diagnosed by right heart catheterization (RHC) were recruited. Patients underwent cardiac magnetic resonance (CMR) and RHC examination within 2 weeks. The CMR images were analyzed to calculate the cardiac functional parameters including right ventricle (RV) and left ventricle (LV) end-diastolic volume index (EDVI), end-systolic volume index (ESVI), stroke volume index (SVI), ejection fraction (EF), tricuspid annular plane systolic excursion (TAPSE), and myocardial mass (MM). The median follow-up time was 46.5 months (interquartile range: 26–65.5 months), and the endpoints were the occurrence of MACE.

Results

RVEDVI, LVEDVI, and LVESVI were higher in congenital heart disease–related PH (CHD-PH) than in other sub-types (p < 0.05). RVMM, RVSVI, and RVCI were highest in CHD-PH. There was no significant difference in the prognosis among different sub-types (p > 0.05). Comparing with the non-MACE group, RVEF, TAPSE, and LVSVI significantly decreased in the MACE group, while the RVESVI significantly increased (p < 0.05). TAPSE ≤ 15.65 mm and LVSVI ≤ 30.27 mL/m2 were significant independent predictors of prognosis in PH patients.

Conclusion

CHD-PH had a higher RV function reserve but lowest LVEF comparing to other subgroups. TAPSE and LVSVI could contribute to the prediction of MACE in PH patients.

Key Points

• CMR imaging is a noninvasive and accurate tool to assess ventricular function.
• CHD-PH had higher RV function reserve but lowest LVEF.
• TAPSE and LVSVI could contribute to the prediction of MACE in PH patients.
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Metadaten
Titel
Indication of the prognosis of pulmonary hypertension by using CMR function parameters
verfasst von
Wen Ren
Jing-Jing Guo
Fan Yang
Zhen-Wen Yang
Tie-Lian Yu
Yuan-Lin Deng
Zhang Zhang
Dong Li
Publikationsdatum
18.03.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 9/2021
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-021-07835-8

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