Erschienen in:

09.04.2024 | Infektionen in der HNO-Heilkunde | CME

Antiseptika in der HNO-Heilkunde – eine Substanzübersicht

verfasst von: Prof. Dr. med. Bernhard Olzowy, Sarina Müller, Natascha Antonia Cidlinsky, Daniela Guderian

Erschienen in: HNO | Ausgabe 6/2024

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Zusammenfassung

Zur präoperativen Hautantisepsis eignen sich alkoholhaltige Jodlösung und Octenidin, für Wundantisepsis zudem Polihexanid und hypochlorige Säure (HOCl), wobei nur Povidon(PVP)-Jod und HOCl mit Knorpel in Kontakt kommen darf. Chlorhexidin sollte nur noch als Mundspüllösung und Körperwaschlotion zur Dekolonisierung bei multiresistentem Staphylococcus aureus (MRSA) angewendet werden. Für die zahlreichen weiteren Rachenantiseptika fehlen Studien zum klinischen Nutzen. Zur Dekolonisierung der Nasenvorhöfe gibt es Polihexanid und Octenidin als Nasen-Gele, sie sind in der MRSA-Dekolonisierung jedoch Mupirocin unterlegen. Zur Nasendusche eignen sich Jodlösung und HOCl, wobei für HOCl ein Nutzen bei chronischer Rhinosinusitis belegt ist. Alle Antiseptika sind mehr oder weniger ototoxisch. Bei intaktem Trommelfell können Isopropylalkohol-Essigsäure-Kombinationen zur Prophylaxe und Therapie der Otitis externa und Myringitis eingesetzt werden, bei perforiertem Trommelfell alkoholfreie Jodlösung und HOCl.

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Titel: Antiseptika in der HNO-Heilkunde – eine Substanzübersicht
verfasst von: Prof. Dr. med. Bernhard Olzowy
Sarina Müller
Natascha Antonia Cidlinsky
Daniela Guderian
Publikationsdatum: 09.04.2024
Verlag: Springer Medizin
Schlagwörter: Infektionen in der HNO-Heilkunde
Rhinosinusitis
Wundinfektion
Pharyngitis
Otitis externa
Hygiene
Pharyngitis
HNO
Erschienen in: HNO / Ausgabe 6/2024
Print ISSN: 0017-6192
Elektronische ISSN: 1433-0458
DOI: https://doi.org/10.1007/s00106-024-01456-5

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