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Erschienen in: Die Urologie 11/2022

12.10.2022 | Infertilität | Leitthema

Umweltfaktoren, Lebensstil und männliche Fertilität

verfasst von: Prof. Dr. med. Hans-Christian Schuppe, Prof. Dr. med. Frank-Michael Köhn

Erschienen in: Die Urologie | Ausgabe 11/2022

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Zusammenfassung

Bei der Erfassung kausaler Faktoren männlicher Fertilitätsstörungen spielen Lebensstil und Umweltfaktoren eine wichtige Rolle. Das Wissen um die Wechselwirkungen zwischen derartigen Einflüssen und reproduktiven Funktionen des Mannes eröffnet zudem die Möglichkeit eines präventiven Ansatzes in der Andrologie. Relevante exogene Noxen sind Genussgifte, Pharmaka einschließlich Lifestyle-Medikamenten, Berufsstoffe, Umweltchemikalien sowie physikalische Faktoren. Reproduktionstoxische Effekte können sich prätestikulär, testikulär oder posttestikulär entfalten und neben einer Beeinträchtigung der Spermatogenese oder Spermienfunktion auch Hormon- und Sexualstörungen verursachen. Aufgrund der komplexen Regulation des männlichen Reproduktionssystems sowie der begrenzten Übertragbarkeit tierexperimenteller Befunde und In-vitro-Daten auf die Situation beim Menschen liegen allerdings nur für wenige Noxen gesicherte Erkenntnisse vor. In der andrologischen Sprechstunde sollten bei Erhebung der Anamnese potenzielle Expositionsrisiken erfasst und die Patienten über eine gesicherte oder mögliche Relevanz für ihre Fertilität aufgeklärt werden.
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Metadaten
Titel
Umweltfaktoren, Lebensstil und männliche Fertilität
verfasst von
Prof. Dr. med. Hans-Christian Schuppe
Prof. Dr. med. Frank-Michael Köhn
Publikationsdatum
12.10.2022
Verlag
Springer Medizin
Erschienen in
Die Urologie / Ausgabe 11/2022
Print ISSN: 2731-7064
Elektronische ISSN: 2731-7072
DOI
https://doi.org/10.1007/s00120-022-01951-z

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