Background
Methods
Study design
Data collection
Clinical assessment
Statistical analysis
Results
Patients
Inflammation between patients with CVT and controls
CVT patients n = 95 | Control individuals n = 41 | P value | |
---|---|---|---|
Age, years | 38.93 ± 13.53 | 40.90 ± 16.70 | 0.469 |
Gender (female, %) | 60 | 63.41 | 0.708 |
Hs-CRP | 3.3 (0.7, 11.73) | 0.5 (0.26, 1.6) | < 0.001 |
IL-6 | 9.49 (5.76, 14.94) | 4.32 (3.01, 5.02) | 0.003 |
NLR | 2.84 (1.86, 3.73) | 2.05 (1.77, 2.59) | < 0.001 |
CSF IgA | 0.4 (0.24, 0.81) | 0.2 (0.13, 0.23) | < 0.001 |
CSF IgM | 1.3 (0.5, 2.6) | 0.04 (0.02, 0.08) | < 0.001 |
CSF IgG | 3.48 (2.22, 5.56) | 2.54 (1.98, 2.88) | 0.001 |
Inflammation and stages of CVT
Inflammation and the severity of CVT
Inflammation and outcome of CVT
Poor condition n = 39 | Good condition n = 56 | P value | |
---|---|---|---|
Female (%) | 27/39 (69.23%) | 30/56 (53.57%) | 0.142 |
Male (%) | 12/39 (30.77%) | 26/56 (46.43%) | 0.142 |
Age, years | 37.62 ± 11.67 | 39.84 ± 14.72 | 0.434 |
Serum Hs-CRP (mg/L) | 4.88 (0.86, 20.42) | 3.06 (0.65, 6.74) | 0.194 |
Serum NLR | 3.45 (2.31, 5.29) | 2.45 (1.72, 3.14) | 0.001 |
Serum IL-6 (pg/ml) | 11.87 (6.50, 14.94) | 8.01 (4.98, 14.94) | 0.451 |
CSF IgA (mg/dl) | 0.46 (0.21, 0.90) | 0.38 (0.38, 0.74) | 0.617 |
CSF IgM (mg/dl) | 1.90 (0.60, 3.00) | 0.95 (0.40, 2.02) | 0.005 |
CSF IgG (mg/dl) | 4.16 (1.87, 6.80) | 3.22 (2.29, 4.96) | 0.423 |
NLR < 4.205 n = 76 | NLR ≥ 4.205 n = 19 | P value | |
---|---|---|---|
Male (%) | 28/76 (36.84) | 10/19 (52.63) | 0.209 |
Female (%) | 48/76 (63.16) | 9/19 (47.37) | 0.209 |
Age, years(mean ± SD) | 38.01 ± 13.23 | 42.58 ± 14.45 | 0.190 |
NIHSS score on admission (median, IQR) | 0.00 (0.00, 1.00) | 2.00 (0.00, 7.00) | < 0.001 |
Seizure (%) | 17/76 (22.37) | 7/19 (36.84) | 0.194 |
Infarction (%) | 28/76 (36.84) | 9/19 (47.37) | 0.400 |
Intracerebral hemorrhage (%) | 7/76 (9.21) | 4/19 (21.05) | 0.149 |
Papilledema (%) | 33/76 (43.42) | 9/19 (47.37) | 0.757 |
Intracranial hypertension (%) | 53/76 (69.74) | 13/19 (68.42) | 0.911 |
Poor outcome (%) | 5/76 (6.58) | 8/19 (42.11) | < 0.001 |