Ausgabe 1/2024
Inhalt (60 Artikel)
- Editorial
History and philosophy of the treatment of rheumatic diseases
K. D. Rainsford, Walter Fairbairn Kean, Colin Andrew Kean
- Original Article
Rheumatoid arthritis
W. Watson Buchanan, Colin A. Kean, Walter F. Kean, K. D. Rainsford
- Review
Treatment of rheumatic musculoskeletal disorders
W. Watson Buchanan, K. D. Rainsford, Colin A. Kean, Walter F. Kean
- Original Article
Sjögren’s syndrome
Geza Balint, W. Watson Buchanan, Colin A. Kean, Walter Kean, K. D. Rainsford
- Original Article
Surgery of joints
W. Watson Buchanan, Michael Graham Hogan, Colin A. Kean, Walter F. Kean, K. D. Rainsford
- Original Article
John Alexander Mullin (1835–1899): The Canadian Physician who first described Osler’s Nodes
W. Watson Buchanan, K. D. Rainsford, Colin A. Kean, Walter F. Kean
- Original Article
The illness of William Soutar (1898–1943)
W. Watson Buchanan, K. D. Rainsford, Colin A. Kean, Walter F. Kean
- Original Article
Clinical therapeutic trials
W. Watson Buchanan, Colin A. Kean, K. D. Rainsford, Walter F. Kean
- Original Article
Spondyloarthropathies and arthritis post-infection: a historical perspective
W. Watson Buchanan, Colin A. Kean, K. D. Rainsford, Walter F. Kean
- Original Article
Medical aspects of the tour by Martin Martin (c 1660–1719) of the Western and Northern Islands of Scotland, Circa 1695
W. Watson Buchanan, K. D. Rainsford, Colin A. Kean, Walter F. Kean
- Original Article
Reactive arthritis: the convoluted history of Reiter's disease
W. Watson Buchanan, Walter F. Kean, K. D. Rainsford, Colin A. Kean
- Review
Natural agents as wound-healing promoters
Negin Akhtari, Mahnaz Ahmadi, Yasaman Kiani Doust Vaghe, Elham Asadian, Sahar Behzad, Hossein Vatanpour, Fatemeh Ghorbani-Bidkorpeh
- Review
NLRs and inflammasome signaling in opioid-induced hyperalgesia and tolerance
Nasrin Zare, Fateme Sharafeddin, AmirMahdi Montazerolghaem, Nastaran Moradiannezhad, Mohammaderfan Araghizadeh
- Review
Insights into the mechanisms of diabetic wounds: pathophysiology, molecular targets, and treatment strategies through conventional and alternative therapies
Jagat Pal Yadav, Ankit Kumar Singh, Maria Grishina, Prateek Pathak, Amita Verma, Vikas Kumar, Pradeep Kumar, Dinesh Kumar Patel
- Open Access
- Review
Therapeutic potential and possible mechanisms of ginseng for depression associated with COVID-19
Fangyi Zhao, Kai Zhang, Hongyu Chen, Tianqi Zhang, Jiayu Zhao, Qianyu Lv, Qin Yu, Mengyu Ruan, Ranji Cui, Bingjin Li
- Open Access
- Review
Pharmacological evaluation of vitamin D in COVID-19 and long COVID-19: recent studies confirm clinical validation and highlight metformin to improve VDR sensitivity and efficacy
Adel A. Gomaa, Yasmin A. Abdel-Wadood, Romany H. Thabet, Ghada A. Gomaa
- Review
Nigella sativa and its chemical constituents: pre-clinical and clinical evidence for their potential anti-SARS-CoV-2 effects
Asha Caroline Cyril, Najma Mohamed Ali, Anagha Nelliyulla Parambath, Cijo George Vazhappilly, Reem Kais Jan, Noushad Karuvantevida, Haneen Aburamadan, Yosra Lozon, Rajan Radhakrishnan
- Review
Linking NLRP3 inflammasome and pulmonary fibrosis: mechanistic insights and promising therapeutic avenues
Shobhit Gairola, Antarip Sinha, Ravinder K. Kaundal
- Review
Targeting cardiovascular risk factors with eugenol: an anti-inflammatory perspective
Sushma Devi, Samrat Chauhan, Ashi Mannan, Thakur Gurjeet Singh
- Review
Mesenchymal stem cell therapy for COVID-19 infection
Seyyed Mohammad Matin Alavi-Dana, Yazdan Gholami, Mohammadreza Meghdadi, Mohammad Saleh Fadaei, Vahid Reza Askari
- Review
Intravenous immunoglobulin for treatment of hospitalized COVID-19 patients: an evidence mapping and meta-analysis
Mei-xuan Li, Yan-fei Li, Xin Xing, Jun-qiang Niu, Liang Yao, Meng-ying Lu, Ke Guo, Mi-na Ma, Xiao-tian Wu, Ning Ma, Dan Li, Zi-jun Li, Ling Guan, Xiao-man Wang, Bei Pan, Wen-ru Shang, Jing Ji, Zhong-yang Song, Zhi-ming Zhang, Yong-feng Wang, Ke-hu Yang
- Review
The effect of acarbose on inflammatory cytokines and adipokines in adults: a systematic review and meta-analysis of randomized clinical trials
Ali Mohammadian, Sahand Tehrani Fateh, Mahlagha Nikbaf-Shandiz, Fatemeh Gholami, Niloufar Rasaei, Hossein Bahari, Samira Rastgoo, Reza Bagheri, Farideh Shiraseb, Omid Asbaghi
- Open Access
- Original Article
Empagliflozin attenuates intestinal inflammation through suppression of nitric oxide synthesis and myeloperoxidase activity in in vitro and in vivo models of colitis
Adam Makaro, Mikołaj Świerczyński, Kacper Pokora, Barbara Sarniak, Radzisław Kordek, Jakub Fichna, Maciej Salaga
- Original Article
Medulla Tetrapanacis water extract alleviates inflammation and infection by regulating macrophage polarization through MAPK signaling pathway
Carsten Tsun-Ka Kwok, Franklin Wang-Ngai Chow, Karry Yuen-Ching Cheung, Xiao-Yi Zhang, Daniel Kam-Wah Mok, Yiu-Wa Kwan, Gabriel Hoi-Huen Chan, George Pak-Heng Leung, Ka-Wang Cheung, Simon Ming-Yuen Lee, Ning Wang, Jing-Jing Li, Sai-Wang Seto
- Open Access
- Original Article
Galantamine mitigates testicular injury and disturbed spermatogenesis in adjuvant arthritic rats via modulating apoptosis, inflammatory signals, and IL-6/JAK/STAT3/SOCS3 signaling
Sara I. Shafiey, Kawkab A. Ahmed, Ali A. Abo-Saif, Amira M. Abo-Youssef, Wafaa R. Mohamed
- Original Article
Immune Response Gene-1 [IRG1]/itaconate protect against multi-organ injury via inhibiting gasdermin D-mediated pyroptosis and inflammatory response
Wenchang Yang, Yaxin Wang, Yongzhou Huang, Tao Wang, Chengguo Li, Peng Zhang, Weizhen Liu, Yuping Yin, Ruidong Li, Kaixiong Tao
- Original Article
PPARγ partial agonist LPSF/GQ-16 prevents dermal and pulmonary fibrosis in HOCl-induced systemic sclerosis (SSc) and modulates cytokine production in PBMC of SSc patients
Anderson Rodrigues de Almeida, Andréa Tavares Dantas, Maria Eduarda de Oliveira Gonçalves, Charlotte Chêne, Mohamed Jeljeli, Sandrine Chouzenoux, Marine Thomas, Eudes Gustavo Constantino Cunha, Lilian David de Azevedo Valadares, João Victor de Melo Gomes, Simão Kalebe Silva de Paula, Marina Galdino da Rocha Pitta, Ivan da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo, Michelly Cristiny Pereira, Angela Luzia Branco Pinto Duarte, Dulcineia Saes Parra Abdalla, Carole Nicco, Frédéric Batteux, Maira Galdino da Rocha Pitta
- Original Article
Sesquiterpene from Artemisia argyi seed extracts: A new anti-acute peritonitis agent that suppresses the MAPK pathway and promotes autophagy
Yinchao Li, Yuanhui Wang, Tianxin Li, Zhenzhen Li, Tao Guo, Guimin Xue, Yongtao Duan, Yongfang Yao
- Open Access
- Original Article
LC-QToF chemical profiling of Euphorbia grantii Oliv. and its potential to inhibit LPS-induced lung inflammation in rats via the NF-κB, CY450P2E1, and P38 MAPK14 pathways
Mai Hussin Radi, Riham A. El-Shiekh, Amany Mohammed Hegab, Shirley Ragae Henry, Bharathi Avula, Kumar Katragunta, Ikhlas A. Khan, Ali M. El-Halawany, Essam Abdel-Sattar
- Open Access
- Original Article
Ameliorative effect of montelukast against STZ induced diabetic nephropathy: targeting HMGB1, TLR4, NF-κB, NLRP3 inflammasome, and autophagy pathways
Ahmed M. Awad, Sally L. Elshaer, Rajashekhar Gangaraju, Rania R. Abdelaziz, Manar A. Nader
- Original Article
Acyclic monoterpenoid-rich essential oil of Cymbopogon distans mitigates skin inflammation: a chemico-pharmacological study
Divya Bhatt, Swati Singh, Munmun Kumar Singh, Anil Kumar Maurya, Amit Chauhan, Rajendra Chandra Padalia, Ram Swaroop Verma, Dnyaneshwar U. Bawankule
- Original Article
Erythropoietin alleviates astrocyte pyroptosis by targeting the miR-325-3p/Gsdmd axis in rat spinal cord injury
Wenshan Shan, Jiawei Wang, Rui Cheng, Yong Xuan, Zongsheng Yin
- Original Article
High-dose ascorbic acid potentiates immune modulation through STAT1 phosphorylation inhibition and negative regulation of PD-L1 in experimental sepsis
Xiaoting Zhang, Wentao Ji, Xiaoming Deng, Lulong Bo
- Original Article
Topical Nigella sativa L. product: a new candidate for the management of diabetic peripheral neuropathy
Seyed-Ali Khodaie, Haniyeh Nikkhah, Nasim Namiranian, Marzie Abotorabi, Maryam Askari, Saeed Hosein Khalilzadeh, Amidoddin khatibi Aghda, Mohammad kamalinejad
- Original Article
Effect of nitro-conjugated linoleic acid on the inflammatory response of murine macrophages activated with lipopolysaccharide derived from Prevotella intermedia
Jung Eun Lee, Ah Rim Lee, Eun-Young Choi, In Soon Choi, Sung-Jo Kim
- Original Article
Systems pharmacology and multi-scale mechanism of Enicostema axillare bioactives in treating Alzheimer disease
Madhana Vigneshwari Gopal Samy, Sasidharan Perumal
- Original Article
Development of gel containing Psidium glaziovianum essential oil has in vitro antimicrobial activity and improves healing of excisional wounds in mice
Wêndeo Kennedy Costa, Valquíria Bruna Guimarães, Beatriz Meyruze Barros da Fonsêca, Magda Rhayanny Assunção Ferreira, Luiz Alberto Lira Soares, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva, Maria Tereza dos Santos Correia, Fábio André Brayner dos Santos, Alisson Macário de Oliveira, Márcia Vanusa da Silva
- Original Article
Protective effect of olopatadine hydrochloride against LPS-induced acute lung injury: via targeting NF-κB signaling pathway
Jaspreet Kaur, Priyanka Rana, Tushar Matta, Rupinder Kaur Sodhi, Khushboo Pathania, Sandip V. Pawar, Anurag Kuhad, Kanthi Kiran Kondepudi, Tanzeer Kaur, Neelima Dhingra, Sangeeta Pilkhwal Sah
- Open Access
- Original Article
Sesamol defends neuronal damage following cerebral ischemia/reperfusion: a crosstalk of autophagy and Notch1/NLRP3 inflammasome signaling
Shorouk Mohamed El-Sayyad, Dina M. Abo El-Ella, Mohamed M. Hafez, Asmaa K. Al-Mokaddem, Bassam Mohamed Ali, Magdy M. Awny, Soad Z. El-Emam
- Original Article
2-Hydroxybenzohydrazide as a novel potential candidate against nociception, inflammation, and pyrexia: in vitro, in vivo, and computational approaches
Gowhar Ali, Nazar Ul Islam, Muhammad Qaim, Rahim Ullah, Muhammad Saeed Jan, Khadija Shabbiri, Muhammad Shafique, Muhammad Ayaz
- Original Article
Anti-inflammatory activity of peiminine in acetic acid-induced ulcerative colitis model
Maryam Ranjbar Bushehri, Nahid Babaei, Hadi Esmaeili Gouvarchin Ghaleh, Gholamreza Khamisipour, Gholamreza Farnoosh
- Open Access
- Original Article
Management of ulcerative colitis by dichloroacetate: Impact on NFATC1/NLRP3/IL1B signaling based on bioinformatics analysis combined with in vivo experimental verification
Esraa Abdel-Nassir Abdel-Razek, Heba M. Mahmoud, Amany A. Azouz
- Open Access
- Original Article
Potential role of SNP rs2071475 in rheumatoid arthritis and inflammatory bowel disease in the East Asian population: a Mendelian randomization study
Bo Wang, Yongqiang Xiong, Ren Li, Shu Zhang
- Original Article
Synthesis, molecular docking, analgesic, anti-inflammatory, and ulcerogenic evaluation of thiophene-pyrazole candidates as COX, 5-LOX, and TNF-α inhibitors
M. J. Nagesh Khadri, Ramith Ramu, N. Akshaya Simha, Shaukath Ara Khanum
- Open Access
- Original Article
L-Carnitine augments probenecid anti-inflammatory effect in monoiodoacetate-induced knee osteoarthritis in rats: involvement of miRNA-373/P2X7/NLRP3/NF-κB milieu
Rawan Mahfouz, Safaa H. El-Rewini, Asser I. Ghoneim, Eman Sheta, Mennatallah A. Ali, Sherihan Salaheldin Abdelhamid Ibrahim
- Open Access
- Original Article
Ibuprofen inhibits anaplastic thyroid cells in vivo and in vitro by triggering NLRP3-ASC-GSDMD-dependent pyroptosis
Haohao Guo, Runsheng Ma, Yifei Zhang, Keyu Yin, Gongbo Du, Fanxiang Yin, Hongqiang Li, Ziyang Wang, Detao Yin
- Original Article
Dietary tannic acid attenuates elastase-induced pulmonary inflammation and emphysema in mice
Nandhine Rajasekar, Deepa Gandhi, Ayyanar Sivanantham, Vilwanathan Ravikumar, Dharma Raj, Sudhakar Gandhi Paramasivam, Sramana Mukhopadhyay, Subbiah Rajasekaran
- Open Access
- Original Article
Resveratrol protects against Schistosoma mansoni-induced liver fibrosis by targeting the Sirt-1/NF-κB axis
Dalia Kamal Mostafa, Maha M. Eissa, Doaa A. Ghareeb, Shaymaa Abdulmalek, Wafaa A. Hewedy
- Open Access
- Original Article
Empagliflozin repurposing in Parkinson’s disease; modulation of oxidative stress, neuroinflammation, AMPK/SIRT-1/PGC-1α, and wnt/β-catenin pathways
Noha Nabil Mohammed, Mariane G. Tadros, Mina Y. George
- Original Article
Inhibition of TLR4, NF-κB, and INOS pathways mediates ameliorative effect of syringic acid in experimental ulcerative colitis in rats
Maryam Ghasemi-Dehnoo, Hossein Amini-Khoei, Zahra Lorigooini, Maryam AnjomShoa, Elham Bijad, Mahmoud Rafieian-Kopaei
- Original Article
Icariin ameliorates the cuprizone-induced demyelination associated with antioxidation and anti-inflammation
Li-Juan Song, Qing-Xian Han, Zhi-Bin Ding, Kexin Liu, Xiao-Xu Zhang, Min-Fang Guo, Dong Ma, Qing Wang, Bao-Guo Xiao, Cun-Gen Ma
- Original Article
Assessment of antiarthritic potential of Asparagus dumosus using formaldehyde and CFA-induced arthritic models in rats via modulation of oxidative stress biomarkers and mRNA expression of IL-1b, IL-6, RANKL, OPG, TNF-α and COX-2
Nimra Nazar, Malik Hassan Mehmood, Rida Siddique, Muhammad Naeem Faisal
- Original Article
Baricitinib relieves DSS-induced ulcerative colitis in mice by suppressing the NF-κB and JAK2/STAT3 signalling pathways
Qiong Wu, Yangyang Liu, Jinmeiqi Liang, Ao Dai, Boyu Du, Xueyan Xi, Lan Jin, Yang Guo
- Original Article
Rheumatoid arthritis is a protective factor against Alzheimer’s disease: a bidirectional two-sample Mendelian randomization study
Guo-Shuai Li, Yong-Ze Yang, Guo-Rong Ma, Peng-Fei Li, Qing-Hao Cheng, An-Ren Zhang, Zhuang-Zhuang Zhang, Fu-Kang Zhang, Xin Yang, Hua Fan, Hong-Zhang Guo
- Original Article
The therapeutic effect of Loranthus parasiticus lignan derivatives on collagen-induced arthritis in rats through the SHBG/NFκB pathway
Jiali Bai, Cong Zhang, Yulin Liu, Nanzhen Kuang, Liangquan Xu, Zhengang Xu, Haiwei Wang, Renping Liu
- Original Article
Gene expression of protein kinase AMP-activated catalytic subunit alpha 1 (PRKAA1), solute carrier family 2 member 1 (SLC2A1) and mechanistic target of rapamycin (MTOR) in metformin-treated type 2 diabetes patients with COVID-19: impact on inflammation markers
Pavlo Petakh, Iryna Kamyshna, Aleksandr Kamyshnyi
- Short Communication
Malvidin alleviates LPS-induced septic intestinal injury through the nuclear factor erythroid 2-related factor 2/reactive oxygen species/NLRP3 inflammasome pathway
Guanglu Wang, Fenfen Ma, Wei Zhang, Yue Xin, Kaixin Ping, Yan Wang, Jingquan Dong
