Ausgabe 1/2026
Inhalt (46 Artikel)
Persistent inflammatory cytokine signature in long Covid-19 patients: a meta-analysis
- Review
Waleska Dornas, João Pedro Reis, Tales Eduardo Belilo, Leonardo Gomes Vaz, Helena Horta Nasser, Maria de Lourdes de Souza Maia, Alexandre Figueiredo, André Gomes Tcherniacovski, Lourdes Coral Contreras Montenegro, Xiaofeng Yang, Helton C Santiago
Lingering echoes of SARS-CoV-2: mechanistic insights and management of long COVID syndrome
- Review
Jagat Pal Yadav, Seema Yadav, Nimesh Kumar Dubey, Indra Pal Yadav, Prateek Pathak, Amita Verma
Therapeutic effects of curcumin on seizure and its mechanisms of action
- Review
Seyed Mehrad Razavi, Zahra Najafi Arab, Yasamin Hosseini, Amirhossein Niknejad, Helia Mavaddat, Saeideh Momtaz, Tannaz Jamialahmadi, Prashant Kesharwani, Amir Hossein Abdolghaffari, Amirhossein Sahebkar
Pulmonary fibrosis in post-COVID-19: epithelial-mesenchymal transition as a key mechanism and target for therapy
- Review
R. Sanjay Ramanan, Krishnaja V. Kesavan, Vilwanathan Ravikumar
Phytochemicals and nanoformulation strategies for rheumatoid arthritis: mechanistic insights, therapeutic advances, and translational challenges
- Review
Mohsen Rahmanian, Sarah Khosropanah, Sepehr Hoseinzadeh Moghaddam, Abulfazl Vatankhah, Ali Haghbin, Fatemeh Oroojalian, Kasim Sakran Abass, Prashant Kesharwani, Amirhossein Sahebkar
Molecular mechanisms and risk factors in rheumatoid arthritis: a comprehensive review
- Review
Avnesh Kumar, Shikha Singh, Falguni Goel, Rupesh Kumar Pandey, Lubhan Singh, Amit Kumar, Vaishali Dobhal
A systematic review of therapeutic and paradoxical roles of tumor necrosis factor α inhibitors in autoimmune blistering diseases
- Review
Yekta Ghane, Ali Ezzatollahi Tanha, Mina Khosravi, Nazila Heidari, Negar Ghotbi, Fateme Salemi, Asma Rasouli, Azadeh Goodarzi
Targeting gasdermin D–mediated pyroptosis: a precision anti-inflammatory strategy for acute and chronic lung diseases
- Review
Vijaya Paul Samuel, Muhammad Afzal, M. Arockia Babu, H. Malathi, Laxmidhar Maharana, Surya Nath Pandey, Haider Ali, Waleed Hassan Almalki, Salem Salman Almujri, K. Benod Kumar
Valorisation of citrus peels: implications for cardiovascular diseases and diabetes management
- Review
Bhanu Marwaha, Supriya Singh Gaur
The melatonin-microbiome axis: a new frontier in gut health for the immunomodulatory, antioxidant and anti-inflammatory properties
- Review
Priyanka Gupta, Biplab Debnath, Sumel Ashique, Mohhammad Ramzan, Sabina Yasmin, Eman Shorog, Shubhrajit Mantry, Mohd Tariq, Sathvik Belagodu Sridhar, Uttam Prasad Panigrahy, Himanshu Sharma, Asif Iqbal, Pranav Kumar Prabhakar, Md Yousuf Ansari
Targeting protein kinase C signaling cascades in alzheimer’s disease: emerging neuroprotective roles of aurothioglucose
- Review
Shiv Kumar Kushawaha, Kanika Vashisht, Himanshu Kumar, Mahendra Singh Ashawat, Ashish Baldi
SARS-CoV-2 infection and gut-lung axis: the potential role of rifaximin
- Review
Taghreed N. Almanaa, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Maii A. Abdelnaby, Athanasios Alexiou, Marios Papadakis, Islam E. Abo-ElFetoh, Gaber El-Saber Batiha
Pharmacological modulation of the PI3K/AKT/GSK3β axis: a new frontier in Alzheimer’s disease treatment
- Review
Saad Misfer Alqahtani, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Mustafa M. Shokr, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha
A review on gut microbiota and migraine severity: a complex relationship
- Open Access
- Review
Noha M. Gamil, Rana M. Ghorab, Reham Z. Elsadawy, Nada M. Khadrawy, Mohamed Abdelhamid, Khalid A. Ismael, Omar A. Mohamed, Mohamed M. Ata, Habiba T. Jalal, Joumana E. Zeidan, Reem T. Rashed, Riham A. El-Shiekh
A mechanistic insight of neuro-inflammation signaling pathways and implication in neurodegenerative disorders
- Review
Amina Shafi, Mariam Akmal, Aisha Sethi, Zunera Chauhdary
Kynurenine pathway in Parkinson’s disease: pathophysiological roles and therapeutic interventions
- Review
Aganta Chakraborty, Priya Chaudhary, Joy Das, Utpal Bhui, Khadga Raj Aran, Md Sadique Hussain, Sumel Ashique, Biplab Debnath
Therapeutic effects and molecular mechanisms of isorhamnetin against pulmonary diseases
- Review
Siyuan Jing, He Meng, Chunling Dong, Bo Li
Effect of Quercetin on inflammatory markers in diabetes mellitus: a systematic review and meta-analysis of animal studies
- Review
Pratyush Sandilya, Amir Ali, Rajeev Bharadwaj, Ramu Adela
Anti-arthritic appraisal of Acorus calamus L. extracts in complete Freund’s adjuvant‑induced arthritic Wistar rats via regulating inflammatory cytokines and OPG/RANKL pathway
- Original Article
Muhammad Usman Bari, Asif Hussain, Bilal Aslam, Zia-ud-Din Sindhu, Muhammad Rehan Sajid, Rifat Ullah Khan
Hydrogen sulphide modifies the therapeutic potential of bone marrow mesenchymal stem cells in an adjuvant-induced polyarthritis rat model through the mitigation of angiogenesis, ectopic lymphoid tissue formation, and osteoclastogenesis
- Open Access
- Original Article
Sara M. El-Sayed, Mohamed R. Mohamed, Mohamed M. Naguib, Hadeer A. Aglan, Hanaa H. Ahmed
Targeting tie-2 receptor with rebastinib (DCC-2036) for angiogenesis Inhibition in early-stage arthritis : enhanced efficacy through liposomal sustained release
- Original Article
Minuk Jeong, Heung-Myong Woo, Jang-Hyuk Yun, Junhyung Kim
Heightened anti-inflammatory and antioxidant effects of bone marrow stem cell-conditioned media with mono and doped TiO2 nanoparticles in Carrageenan-induced inflammation
- Open Access
- Original Article
Mohamed S. Kishta, Ahmed M Youssef, Mohamed I. El-Khonezy, Soheir E. Kotob, Nayera E. Hassan, Ahmed A. Abd-Rabou
Dexamethasone modulates cytokine and chemokine secretion by CD4 + T cells from SSc patients and exerts antifibrotic effects in HOCl-induced SSc mice
- Original Article
Maria Eduarda de Oliveira Gonçalves, Anderson Rodrigues de Almeida, Andréa Tavares Dantas, Karen Steffani Silva Florencio, Júlia Roberta da Silva Ferreira, Felipe Henrique dos Santos Barbosa, Ryan Cordeiro Silva, Anderson Arnaldo da Silva, Daniel Neri da Matta, Angela Luzia Branco Pinto Duarte, Moacyr Jesus Barreto de Melo Rêgo, Michelly Cristiny Pereira, Maira Galdino da Rocha Pitta
Diacerein ameliorates acute urarthritis in rats through the Nrf-2/HO-1 and NF-κB pathways
- Original Article
Guohua Cheng, Zhiteng Li, Lin Zhang, Boyun Wu
Fluvoxamine attenuates inflammation in experimental sepsis via novel non-canonical pathways
- Original Article
Luis H. A. Costa, Isis P. Trajano, Wanderson S. Santos, Katiuscia M. Araújo, Luiz G. S. Branco
Inhibitor of hyaluronic acid synthesis 4-methylumbelliferone (4-MU) as a potential anti-inflammatory substance in acute neuroinflammation model in vivo
- Original Article
Dmitry V. Chistyakov, Arina I. Nikolskaya, Vladislav O. Gorbatenko, Sergei V. Goriainov, Denis N. Silachev, Marina G. Sergeeva
Neuroprotective effects of SRS11-92 against oxidative stress–induced senescence via Nrf2/HO-1/NF-κB in Alzheimer’s disease models
- Open Access
- Original Article
Yu Guo, Huan Cao, Chengchao Zuo, Yaqi Huang, Zhongya Gu, Yu Song, Xiang Chen, Qingqing Jiang, Furong Wang
Stigmasterol attenuates nociplastic pain and fatigue-like symptoms in a reserpine-induced fibromyalgia model in mice
- Original Article
Ana Clara Perazzio, João Pedro V. Lopes, Gabriela Becker, Evelyne Silva Brum, Sara Marchesan Oliveira
Anti-inflammatory and neuroprotective effect of bryodulcosigenin against cerebral ischemia/reperfusion injury via modulation of inflammatory signaling pathways
- Original Article
Xiaoran Zhang, Bohu Liu, Dongchuan Shao, Zhe Li, Xiwen Lin, Zhiwei Cao, Wenbiao Huang, Ankit Kumar, Tianhong Wang, Nan Zhao
Integrative network pharmacology and experimental validation of rubus ulmifolius leaf extract in a rat model of MRSA-infected wounds
- Original Article
Essam M Alharshani, Seham S. El-Hawary, Mohamed F. Abdelhameed, Shaymaa Abdalla Ismail, Farid N. Kirol-los, Essam M Abdelkader, Mohamed A. Rabeh, Saad A. Alshehri, Mohamed A. El Raey, E. M. Al, S. A. I
Hepatoprotective potential of Urochloa distachya (L.) ethanol extract against paracetamol and CCl4-induced liver injury in rats
- Original Article
Smrutiranjan Dash, Rajasekaran Sidhan, Sandeep Kumar Mishra, Santosh Kumar Prajapti
Ardisiacrispin B, a natural triterpenoid saponins, suppresses dextran sulfate sodium-induced inflammatory bowel disease by rebalancing the gut microbiota and Th17/Treg of mice
- Original Article
Yongdui Ruan, Yitong Chen, Weijie Peng, Yuting Duan, Qing Luo, Hidayat Ullah, Muhammad Majid, Hoi Leong Xavier Wong, Yanfeng Xie, Weibo Dai, Xianjing Hu
Diphenyleneiodonium exhibits protective effects against both nociception and gastrointestinal inflammation in vivo
- Original Article
Ahmed Kouki, Abdelaziz Souli, Dorsaf Bouzazi, Salwa Bouabdallah, Wafa Ferjani, Pham My-Chan Dang, Mossadok Ben-Attia, Jamel El-Benna
Repurposing amlexanox as a topical anti-inflammatory and antioxidant intervention for diabetic foot ulcers: insights from in-silico and in-vivo studies
- Original Article
Nishika Kapoor, Navneet Dhaliwal, Jatinder Dhaliwal, Kanwaljit Chopra
Citral impairs intestinal changes caused by ulcerative colitis through modulation of antioxidant, anti-inflammatory and healing activities
- Original Article
Maycon T. Emílio-Silva, Vinícius P. Rodrigues, Antonio J. Ruiz-Malagon, Isabela G. Guidolin, Felipe L. Dario, Mariana M. Fioravanti, Alba Rodriguez-Nogales, Julio Gálvez, Clelia A. Hiruma-Lima
Neuroprotective mechanism of syringic acid targeting oxidative damage and neuroinflammation in an experimental model of traumatic brain injury
- Original Article
Rittu Banderwal, Anil Kumar
The sesquiterpene lactone components of Cichorium glandulosum suppress both in vitro and in vivo inflammatory responses by reducing IL-1β levels
- Original Article
Xiaoyan Ma, Yang Li, Shuwen Qi, Chunzi Zhang, Juan Zhang, Tuxia Pang, Wenhui Hou, Xiaoli Ma
Unveiling phytoconstituents and the anti-inflammatory potential of Crassula tetragona L. in ulcerative colitis: A focus on the PPARγ/SIRT1 axis
- Open Access
- Research
Mona A. Raslan, Rehab F. Abdel-Rahman, Hany M. Fayed, Marawan A. Elbaset, Rehab F. Taher
Metformin alleviates presbycusis by activating the SIRT1/PINK1/GPX4 pathway in vitro and in vivo
- Research
Chaojun Zeng, Wei Lin, Xi Gu, Xihang Chen, Yanchun Lin, Yuqing Chen, Zhifeng Chen, Chang Lin
Sodium alginate-encapsulated Colchicum nanoparticles attenuate TNF-α and NF-κB signaling in macrophages: A novel therapeutic strategy for rheumatoid arthritis
- Research
Hasan Ege, Fulya Dal Yontem, Ibrahim Sirri Yuzbasioglu, Sude Naz Cataltepe, Erdi Bulus, Yusuf Can Gercek, Yesim Muge Sahin, Zeynep Ruya Ege
Dual anti-inflammatory and immunomodulatory effects of clove essential oil and eugenol: targeting neutrophil functions and experimental arthritis
- Research
Othman El Faqer, Zaynab Ouadghiri, Hicham Wahnou, Ismail Elkoraichi, Abdelmoiz El Faqer, Asmae Mazti, Samira Rais, El Mostafa Mtairag
Anti-arthritic potential of Cassia fistula leaf extracts and sennoside B via NF-κB inhibition: In vivo and in vitro pre-clinical study
- Research
Aashcharya U. Mishra, Sumati Sen, Meenu Devi, Abhishek K. Rai, Ratnasekhar Ch, Dnyaneshwar U. Bawankule, Daya N. Mani
Ivarmacitinib provides rapid and continuous improvement in patients with moderate-to-severe atopic dermatitis: a focus on different anatomical regions
- Research
Feng Xiong, Bingjing Zhou, Siting Huang, Jie Li, Qiaozhi Cao, Meiyun Jiang, Qiqi Jia, Xinyu Shui, Shuying Li, Xiaoqing Yi, Pian Yu
Editorial Expression of Concern: Arabincoside B isolated from Caralluma arabica as a potential anti‑pneumonitis in LPS mice model
- Open Access
- Editorial Expression of Concern
Riham A. El‑Shiekh, Ghazal Nabil, Aya A. Shokry, Yasmine H. Ahmed, Othman S. S. Al‑Hawshabi, Essam Abdel‑Sattar
Editorial Expression of Concern: Bioactive fraction from Plumeria obtusa L. attenuates LPS‑induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF‑MS and molecular docking
- Open Access
- Editorial Expression of Concern
Yousra T. Eloutify, Riham A. El‑Shiekh, Khaled Meselhy Ibrahim, Ahmed R. Hamed, Ahmed A. Al‑Karmalawy, Aya A. Shokry, Yasmine H. Ahmed, Bharathi Avula, Kumar Katragunta, Ikhlas A. Khan, Meselhy R. Meselhy
Retraction Note: Molecular insights of eucalyptol (1,8-Cineole) as an anti-arthritic agent: in vivo and in Silico analysis of IL-17, IL-10, NF-κB, 5-LOX and COX-2
- Retraction Note
Urooj Iqbal, Abdul Malik, Nabeela Tabassum Sial, Ambreen Malik Uttra, Muhammad Fayyaz ur Rehman, Malik Hassan Mehmood
