Ausgabe 10/2025
Inhalt (43 Artikel)
Stem cell therapy: a promising frontier in modern medicine with a comprehensive overview of their biology and potential therapeutic applications in chronic non-healing cutaneous injuries
- Review
Qadeer Ahmad, Shumaila Mehdi, Malik Hassan Mehmood, Muhammad Talha Asif, Muhammad Mohsin Ali
Targeting NLRP3 inflammasome with curcumin: mechanisms and therapeutic promise in chronic inflammation
- Review
Surya Nath Pandey, M. Arockia Babu, Kavita Goyal, Soumya V. Menon, Subhashree Ray, Mandeep Kaur, Swati Sharma, Mohit Rana, A. Rekha, Haider Ali, Sachin Kumar Singh, Gaurav Gupta
Effect of pentoxifylline on serum levels and gene expression of inflammatory markers: a systematic review and meta-analysis of randomized controlled trials
- Review
Banafsheh Safizadeh, Sahar Yarahmadi, Farzad Sadri, Elham Bahreini, Yaser Mohammadi, Taraneh Rezaei
Analgesic and anti-inflammatory properties of carbenoxolone: a review
- Review
Hamid Ahmadpourmir, Hananeh Mohammadi Tabar, Zahra Gholamnezhad, Vahideh Ghorani, Seyedeh Faezeh Taghizadeh, Konstantinos Tsarouhas, Mahmoud Hashemzaei, Ramin Rezaee
Role of dexmedetomidine in brain injury: a systematic review
- Open Access
- Review
Rania Zekry, Rehab H. Werida, Ehab S. Hegazy, Tarek M. Mostafa
Resveratrol: potential therapeutic effects on ocular health
- Review
Bennett Kurien Biju, Marina Andavar
The neuroinflammatory triumvirate: NF-κB, NLRP3, and mTOR in spinal cord injury
- Review
Ali Darabniya
Beyond the blood–brain barrier: unraveling T cell subsets in CNS immunity and disease
- Open Access
- Review
Mustafa M. Shokr
Role of long non-coding RNAs in the pathogenesis of gastric cancer-induced by Helicobacter pylori
- Review
Zeynab Marzhoseyni, Foroogh Neamati, Mansoor Khaledi, Mohammad Hossein Haddadi, Aydin Sadeghi, Mina Yekani, Mohammad Yousef Memar
Targeted biologic therapies and advanced drug delivery approaches in asthma management: a clinical perspective
- Review
Nousheen Khatoon, Anjila Firdous, Meenakshi Hirwani, Ayushmaan Roy, Mohammad Adnan Raza, Ajazuddin
Salidroside and inflammation-linked disorders: integrative insights into the pharmacological effects and mechanistic targets
- Review
M. V. N. L. Chaitanya, Deepshikha Patle, Sachin Kumar Singh, Avijit Mazumder, Rakesh Kumar Sindhu, Kamal Dua, Navneet Khurana, Prince Arora
Efficacy and safety of Mirikizumab in the treatment of moderate to severe inflammatory bowel diseases: a systematic review and updated meta-analysis
- Review
Joel Gabin Konlack Mekontso, Joseph Yvan Bena Nnang, Samuel G. J. Fodop, Bishoy I. B. Elkoumes, Guy Loic Nguefang Tchoukeu, Anifatou B. Kortim, Ticha B. T. Tembi, Akil Olliverre, Jarin Prasa, John Trillo
Interleukin-10 family cytokines: key regulators and novel therapeutic targets for respiratory diseases
- Review
Pouya Goleij, Alireza Amini, Sajad Abolfazli, Mohammad Mahdi Heidari, Mohammad Amin Khazeei Tabari, Michael Aschner, Danaé S. Larsen, Haroon Khan, Maria Daglia
Anti-inflammatory effects of Calebin A on metabolic syndrome via NF-κB signaling pathway modulation
- Review
Mansuor A. Alanazi
Targeting the awry Aβ pathway in Alzheimer’s disease: hype and hurdles
- Review
Hayder M. Al-kuraishy, Ghassan M. Sulaiman, Ali I. Al-Gareeb, Hamdoon A. Mohammed, Ali K. Albuhadily, Mosleh M. Abomughaid
Update on metformin for osteoarthritis treatment
- Review
Ben-Zheng Li, He-Xin Wei, Shu-zhi Li, Yong-Ze Yang, An-Ren Zhang, Hong-Zhang Guo
Targeting mGluR7 in Parkinson’s disease: a novel approach to neuroprotection and synaptic therapies
- Review
Gursimran Singh, Khadga Raj Aran
Pharmacological interventions targeting β-adrenoceptors in colorectal cancer: an evolving paradigm
- Open Access
- Review
Aya Ghosn, Khalil Bassam, Mohammad Al Zein, Suzanne A. Nasser, Gianfranco Pintus, Ali H. Eid
Evaluating the preclinical efficacy of naringenin in rheumatoid arthritis: a meta-analysis of in vivo studies
- Original Article
Muhammad Muzammil Nazir, Ayesha Batool, Muhammad Asad Sajid, Asma Ashraf
The impact of alpha-lipoic acid treatment on various mediators of inflammatory and immune responses in a murine arthritis model
- Original Article
Mohamad M. Aboelenin, Mohamed Hefnawy, Talha Bin Emran, Heba I. Shafey, Khairy M. A. Zoheir
Antinociceptive, anti-inflammatory, and antiophidic potential of Punica granatum leaves extract and fraction: an in vitro and in vivo evaluation
- Original Article
Janaina Carla Barbosa Machado, Joyce Cristina da Silva, Wêndeo Kennedy Costa, Márcia Vanusa da Silva, Alisson Macário de Oliveria, Alessandra Daniele-Silva, Adriana Marina e Silva Parente, Sarah de Sousa Ferreira, Diana Pontes da Silva, Manoela Torres-Rêgo, Felipe França Cavalcanti, Matheus de Freitas Fernandes-Pedrosa, Magda Rhayanny Assunção Ferreira, Luiz Alberto Lira Soares
Targeting the cytokine–redox axis: dose-dependent immunomodulation by methotrexate in a biomarker-guided ovine endotoxaemia model
- Original Article
Armin Amirian, Aliasghar Chalmeh, Mehrdad Pourjafar, Zahra Akhlaghi Moghaddam
Dexketoprofen enhances NLRP3 activation via ATPase activity after canonical stimuli
- Open Access
- Original Article
Daniel Boy-Ruiz, Juan Miguel Suarez-Rivero, Inés Muela-Zarzuela, Mario D. Cordero
Jasmine sambac L. essential oil attenuates inflammation and pain via TRPV1
- Original Article
Sahar Jaffal, Aluck Thipayarat, Samer Alqaraleh, Jakrapop Wongwiwat, Pattarin Supanivatin
Potentiation of analgesic activity following the complexation of Algrizea minor Sobral, Faria & Proença (Myrteae, Myrtaceae) leaf essential oil with β-cyclodextrin
- Original Article
Paulo Henrique Eloi Fernandes, Bruno Oliveira de Veras, Paulo Henrique Andrade do Nascimento Silva, Júlio César Ribeiro de Oliveira Farias de Aguiar, Daniela Maria do Amaral Ferraz Navarro, Maria Tereza dos Santos Correia, Márcia Vanusa da Silva
The hydroalcoholic extract of the leaves of red mombin (Spondias purpurea L.) is more effective in accelerating ulcer healing than preventing them in rodents
- Original Article
Ruan Kaio Silva Nunes, Bruna Longo, Caio Henrique Willrich, Levy Mota da Silva, Luísa Santiago, Thiago Farias de Queiroz Silva, Lucas Matheus Lessa de Olinda, Layla Francielle Pereira, Heloisa Immianovsky Eisendecker, José Roberto Santin, Larissa Benvenutti, Luiza Felipim Corsi, Bianca Priscila Miranda, Hydima Julião Cóta, Larissa Venzon, Tauani Caroline Santos França, Max Vidal-Gutiérrez, Zuleide Maria Ignacio, Walter Antônio Roman-Junior, Luísa Mota da Silva
Effects of low omega-6/omega-3 ratio and high omega-9/omega-6 ratio oil blend on inflammation and oxidative stress after tooth extraction in rats
- Original Article
Radamés Bezerra Melo, Gabriella Alves Julião Costa, Paulo Goberlânio de Barros Silva, Reinaldo Barreto Oriá, Cristhyane Costa de Aquino, Paulo Roberto Leitão Vasconcelos
Genetic insights into the relationship between anti-inflammatory drug target genes and oral diseases
- Open Access
- Original Article
Zelong Hu, Yuchong Xie, Huike Wang, Shouqiang Zhu, Shijia Huang, Minzhe Xin, Haonan Ding, Yuxin Qian, Yingnan Tian, Xuwen Wang, Minxin He, Lei Jin
Gastroprotective effect of nifuroxazide against indomethacin-induced gastric ulcers in rats via modulation of Nrf2/HO-1, HMGB1/TLR4/NF-κB p65, and apoptotic caspase-3 signaling pathways
- Original Article
Sara S. Aboelmagd, Dina M. Khodeer, Ahmed E. Khodir, Naglaa F. EL-Orabi
Macroscopic and microscopic evaluation of the therapeutic effects of fosfomycin on surgical wound healing in a rat model
- Original Article
Ali Darabniya, Mahdi Darabniya, Shahrzad Jalilpour Rezaei, AmirReza Davoodi, Elham Azarmehr, Sara Shokrpoor, Sakineh Khanamani Falahatipour
Molecular research: the effect of black fig (Ficus carica L.) leaf extract on inflammation in punch skin biopsy
- Open Access
- Original Article
Sinem Gültekin Tosun, Esra Balcıoğlu, Korhan Arslan, Gülce Yıldız, Bilal Akyüz
Potential repurposing of lapatinib and pazopanib as neuroprotective agents in a rat model of Huntington’s disease
- Open Access
- Original Article
Nada Ezeldine-Elmahalawy, Noha F. Abdelkader, Hala F. Zaki, Amany I. Elbrairy, Sameh S. Gad
Inflammopharmacological perspectives on plant-derived compounds: ınteraction with monkeypox virus receptors
- Original Article
Faik Gökalp
Neuroprotective effects of candesartan in 3-nitropropionic acid-induced Huntington’s disease: modulation of angiotensin and CREB/BDNF/PGC1-α signaling
- Open Access
- Original Article
Ali M. Elgindy, Ahmed M. Atwa, El-Sayed E. El-Awady, Norhan M. El-Sayed, Naglaa F. El-Orabi
Unveiling the secret of cellular metamorphosis: the crucial role of EndMT mechanisms in COVID-19-induced pulmonary fibrosis
- Original article
Xin Zhang, Xia Tong, Ruijie Hou, Pengbo Wang, Yan Mo, Lanlan Zhang
Joint disorders and ozone therapy: some comments
- Commentary
Marianno Franzini, Luigi Valdenassi, Salvatore Chirumbolo
Ozone therapy and the role of the glutathione pathway
- Short Communication
Salvatore Chirumbolo, Marianno Franzini, Umberto Tirelli, Luigi Valdenassi
In vitro antioxidant activity and in vivo antinociceptive and anti-inflammatory effects of the hydroethanolic extract from leaves of Myrciaria floribunda (H. West ex Willd.) O. Berg in Swiss mice
- Original Article
Izabelly Bianca da Silva Santos, Simone Patricia de Freitas Rosa, Wendel César eSilva Pereira, Bruno Souza dos Santos, Natanael Teles Ramos de Lima, José Maria Barbosa Filho, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Maria Tereza dos Santos Correia, Wêndeo Kennedy Costa, Marcia Vanusa da Silva
Limonene alleviated ulcerative colitis via anti-inflammation, anti-oxidation and regulating intestinal microenvironment in vivo and in vitro
- Original Article
Wenxiu Xu, Hongbo Wang, Zhenyu Sun, Hui Zhang, Zhijun Zhang, Xiangrong Sun, Jiayu Gu, Yanling Gong
Correction: Ipomoea carnea Jacq. ameliorates formalin-induced paw inflammation in rats through modulation of oxidative and inflammatory pathways
- Correction
Shabab Nasir, Muhammad Usman, Humaira Gul, Malik Saadullah, Maryam Farrukh, Rida Siddique, Bushra Shaukat, Abdullah R. Alanzi, Ana Sanches Silva, Muhammad Ajmal Shah
