Ausgabe 2/2026
Inhalt (28 Artikel)
Narrative review on the development of multi-target pharmacological agents for the management of rheumatoid arthritis
- Review
Yarava Dhanush, Vakkalagadda Siva Ganesh
Diosgenin-mediated NF-κB and MAPK pathway modulation for osteoarthritis treatment: molecular mechanisms, bioavailability enhancement, and therapeutic applications
- Open Access
- Review
Rudresh Adarkar, Vijishna Lekshmi Viswambharan, Akanksha Dessai, Richard Lobo, Vamshi Krishna Tippavajhala, Vasudev Pai, Chandrashekar Kodangala Subraya, H. N. Aswatha Ram
Exploring the mechanisms and therapeutic role of γ-oryzanol in neuropathic pain: a systematic review
- Review
Abhishek Chauhan, Raj Kamal, Mohit Kumar, Thakur Gurjeet Singh, Sukriti Vishwas, Ankit Awasthi
Natural products as HMG-CoA reductase inhibitors (statins) for the management of non-communicable diseases
- Open Access
- Review
Radwa N. Muhammad, Nora M. Aborehab, Shaza H. Aly, Noha N. Nasr, Merhan O. Hindam, Aya M. Mustafa, Safaa A. Faheem, Mariam H. Fawzy, Mohammed E. Abo-El Fetoh, Ahmed M. El-Dessouki, Mostafa A. Rabie, Riham A. El-Shiekh, Mahmoud E. Youssef
From nutrition to therapeutics: the diverse inflammopharmacological and biomedical roles of astaxanthin
- Open Access
- Review
Heba R. Ghaiad, Riham A. El-Shiekh, Ahmed M. Atwa, Aya M. Mustafa, Ali M. Elgindy, Mahmoud Abdelrahman Alkabbani, Weam A. Elkady, Kawther Magdy Ibrahim
NLRP3 inflammasome and Alzheimer’s disease: bridging inflammation and neurodegeneration
- Review
Rufaida Wasim, Sumaiya Azmi, Asad Ahmad, Akash Srivastava
Sodium-glucose cotransporter-2 inhibitors and sepsis: a story with two tails or with one tail?
- Review
Baris Afsar, Rengin Elsurer Afsar, Katherine Tuttle, Krista L. Lentine
Therapeutic potential of plant-derived tannic acid on pulmonary disorders in experimental models
- Review
Yokeshwaran Punniyasekaran, Bhagyashree Meena, Harsha Akshaylal Pal, Pushpendra Kumar Namdeo, Sudhakar Gandhi Paramasivam, Subbiah Rajasekaran
Polycystic ovary syndrome (PCOS): current insights, emerging therapeutics, and future treatment strategies
- Review
Mitali Panchpuri, Anglina Kisku, Ritu Painuli, Gaurav Pant, Chetan Kumar
Cannabinoid type 2 receptor crosstalk and microglial plasticity—shaping the balance between neuroinflammation and repair
- Review
Shlok Bodke, Lokesh Kumar Bhatt
Targeting PKC/NF-κB/NLRP3-driven NcRNA neuroinflammatory crosstalk by condensed tannins in global cerebral ischemia
- Review
Pradeep Kant Pachauri, Siva Prasad Panda
Efficacy and safety of tapinarof in atopic dermatitis: a frequentist and bayesian meta-analysis of randomized controlled trials
- Review
Rachita Meher, Archana Mishra, Anand Srinivasan, Rituparna Maiti, Debasish Hota
Formulation and characterization of escin loaded-chitosan nanoparticles and assessment of its anti-arthritic potential in Wistar rats: a mechanistic approach
- Research
Ayesha Riaz, Ammara Saleem, Muhammad Furqan Akhtar
Long COVID: a review of mechanisms and treatment modalities
- Original Article
Mabel Yet, Hui Sheung Teo, Hannah Kwa, Joseph Yeo, Samuel S. Y. Wang
Anti-osteoarthritic effects of stem bark extract of Anogeissus latifolia: a comprehensive in-vivo study
- Original Article
Chaitanya B. Sirsath Patil, Shreyas R. Shinde, Riddhi S. Deka, Akshay M. Baheti, Shuchi Nagar, Shvetank Bhatt, Anil T. Pawar
Evaluation of the antimigraine and anti-neuroinflammatory activity of purified constituents of Petasites hybridus L. in a migraine-like pain model in mice
- Research
Łukasz Kulinowski, Katarzyna Targowska-Duda, Diana Pietrzak-Mitura, Akanksha Mudgal, Benita Hryć, Łukasz Kurach, Maciej Korczak, Jakub Piwowarski, Simon Vlad Luca, Barbara Budzyńska, Krystyna Skalicka-Woźniak
Drimiopsis maculata methanol extract attenuates inflammation in experimental rat model of polyarthritis: a biochemical and molecular insight
- Research
Malik Saadullah, Farwa Tahir, Maryam Farrukh, Samina Afzal, Rabia Munir, Usman Ashraf, Uzma Saleem, Muhammad Ajmal Shah, Ibrahim Aljaezi, Ana Sanchez Silva, Norah K. Algarzae, Musaad Bedah Alsahly
Anti-inflammatory efficacy of a novel diclofenac-loaded liposomal gel in carrageenan-induced paw edema model: a preclinical and radiographic study
- Original Article
Om Prakash Katare, Shruti Chopra, Nitasha Chauhan, Amit Bhatia
Esculetin mitigates mast cell-mediated allergic inflammation and anaphylaxis by suppression FcεRI signaling
- Open Access
- Original Article
Daheen Kim, Jieun Yoon, Na-Hee Jeong, Young-Ae Choi, Meiling Jin, Soyoung Lee, Sang-Hyun Kim
Trans-Chalcone alleviates overt pain-like behavior by targeting the activation of nociceptive neuron TRPV1 and TRPA1 channels
- Open Access
- Research
Maiara Piva, Kelly M. Yaekashi, Thais G. O. Pereira, Mariana M. Bertozzi, Felipe A. Pinho-Ribeiro, Cássia Calixto-Campos, Doumit Camilios-Neto, Sergio M. Borghi, Ana C. Zarpelon-Schutz, Victor Fattori, Rubia Casagrande, Waldiceu A. Verri Jr
Anti-arthritic effect of Helicteres isora L. ethanolic extract via modulation of cytokines and oxidative stress in CFA-induced arthritic rats
- Research
Muhammad Muzammil Nazir, Azhar Rafique, Salma Sultana, Asma Ashraf
Alkaloid fraction of Duguetia furfuracea demonstrated anti-inflammatory and antinociceptive effects through decrease of tumour necrosis factor alpha in mice models
- Original Article
João Paulo Costa Rodrigues, Fellipe Alexandre Alves Moraes, Flávio Martins de Oliveira, Débora de Oliveira Lopes, Flávia Carmo Horta Pinto, Aline Aparecida Saldanha, Arthur Ladeira Macedo, Carlos Alexandre Carollo, João Máximo de Siqueira, Adriana Cristina Soares
Montelukast alleviates levels of inflammatory factors and chemokines in patients with allergic rhinitis
- Original Article
Bo Ru, Wenbo Jiang
Topical 10% sulfasalazine ointment attenuates imiquimod-induced psoriasiform inflammation in mice compared with clobetasol
- Original Article
Mohammed Abdul Muttalib Abdul Bari
Wild chrysanthemum essential oil alleviates dry eye disease by inhibiting NF-κB-mediated inflammation
- Original Article
Shunxin Tang, Mengrui Cai, Fujia Li, Kunlun Li, Chen Zhao, Lin Zhao, Le Su, Qiulin Yue, Song Zhang
Screening of active constituents in camellia oil against atopic dermatitis via molecular docking and experimental validation: elucidation of the underlying molecular mechanism
- Research
Xin Chen, Quanchen Shen, Runcheng Zhou, Yueqiao Lin, Tong Zhou, Kecan Chen, Pengxue Wang, Yanman Chen, Hui Liu, Anping Yang
Editorial Expression of Concern: Antinociceptive and antiedema effects produced in rats by Brassica oleracea var. italica sprouts involving sulforaphane
- Open Access
- Editorial Expression of Concern
Omar Guadarrama-Enríquez, Gabriel Fernando Moreno-Pérez, María Eva González-Trujano, Guadalupe Esther Ángeles-López, Rosa Ventura-Martínez, Irene Díaz‑Reval, Agustina Cano-Martínez, Francisco Pellicer, Nieves Baenas, Diego A. Moreno, Cristina García-Viguera
