Ausgabe 3/2023
Inhalt (35 Artikel)
The amyloid hypothesis revisited: are monoclonal antibodies truly effective?
- Editorial
Joel Ross, Izhar Hasan
Diabetes as one of the long-term COVID-19 complications: from the potential reason of more diabetic patients’ susceptibility to COVID-19 to the possible caution of future global diabetes tsunami
- Review
Yasamin Sharbatdar, Ronak Mousavian, Seyed Mostafa Noorbakhsh Varnosfaderani, Fatemeh Aziziyan, Mahsa Liaghat, Payam Baziyar, Ali Yousefi Rad, Chanour Tavakol, Amir Mansour Moeini, Mohsen Nabi-Afjadi, Hamidreza Zalpoor, Fatemeh Kazemi-Lomedasht
Microglia polarization in nociplastic pain: mechanisms and perspectives
- Open Access
- Review
Ahd A. Atta, Weam W. Ibrahim, Ahmed F. Mohamed, Noha F. Abdelkader
Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases
- Review
Mahvash Sadeghi, Sajad Dehnavi, Ali Asadirad, Suowen Xu, Muhammed Majeed, Tannaz Jamialahmadi, Thomas P. Johnston, Amirhossein Sahebkar
A review on curcumin colon-targeted oral drug delivery systems for the treatment of inflammatory bowel disease
- Review
Hossein Shahdadi Sardou, Paria Rahnama Vosough, Mohammadreza Abbaspour, Abbas Akhgari, Thozhukat Sathyapalan, Amirhossein Sahebkar
Long-term use of metformin and Alzheimer’s disease: beneficial or detrimental effects
- Review
Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Hebatallah M. Saad, Gaber El-Saber Batiha
Crosstalk between phytochemicals and inflammatory signaling pathways
- Review
Sonima Prasad, Vishal Kumar, Charan Singh, Arti Singh
The effect of Nigella sativa (black seed) on biomarkers of inflammation and oxidative stress: an updated systematic review and meta-analysis of randomized controlled trials
- Review
Zeynab Kavyani, Vali Musazadeh, Sahar Golpour-hamedani, Amir Hossein Moridpour, Mahdi Vajdi, Gholamreza Askari
Thalidomide interaction with inflammation in idiopathic pulmonary fibrosis
- Open Access
- Review
Nikitha Naomi Dsouza, Varun Alampady, Krishnaprasad Baby, Swastika Maity, Bharath Harohalli Byregowda, Yogendra Nayak
Review of natural compounds for potential psoriasis treatment
- Open Access
- Review
Omali Y. Elkhawaga, Mohamed M. Ellety, Sheref O. Mofty, Mohamed S. Ghanem, Abdallah O. Mohamed
Nanomedicines: intervention in inflammatory pathways of cancer
- Review
Firoz Anwar, Salma Naqvi, Saiba Shams, Ryan Adnan Sheikh, Fahad A. Al-Abbasi, Amer H. Asseri, Mirza Rafi Baig, Vikas Kumar
Immune cell targeted fumaric esters support a role of GPR109A as a primary target of monomethyl fumarate in vivo
- Original Article
Simon Straß, Johanna Geiger, Natascha Cloos, Nadja Späth, Sophia Geiger, Anna Schwamborn, Luciano De Oliveira da Cunha, Mariella Martorelli, Jan-Hinrich Guse, Thaisa Lucas Sandri, Michael Burnet, Stefan Laufer
Cassia absus-mediated upregulation of IL-4, IL-10 and downregulation of IL-1β, IL-6, TNF- α, NF-κB, IFN-γ in CFA-induced arthritis model
- Original Article
Bazgha Gul, Rukhsana Anwar, Mohammad Saleem, Afifa Noor, Muhammad Ihsan Ullah
Hepatic and cardiac implications of increased toxic amyloid-beta serum level in lipopolysaccharide-induced neuroinflammation in rats: new insights into alleviating therapeutic interventions
- Open Access
- Original Article
Mai M. Anwar, Abeer A. Mabrouk
New insights on mode of action of vasorelaxant activity of simvastatin
- Original Article
Kanika Verma, Rahul Shukla, Jaya Dwivedi, Sarvesh Paliwal, Swapnil Sharma
Pterostilbene reduces the progression of atopic dermatitis via modulating inflammatory and oxidative stress biomarkers in mice
- Original Article
Yasmin Bangash, Ammara Saleem, Muhammad Furqan Akhtar, Fareeha Anwar, Bushra Akhtar, Ali Sharif, Muhammad Imran Khan, Aslam Khan
Attenuation of COX-2 enzyme by modulating H2O2-mediated NF-κB signaling pathway by monoamine oxidase inhibitor (MAOI): a further study on the reprofiling of MAOI in acute inflammation
- Original Article
Debjeet Sur, Chaitali Mondal, Ashok Kumar Balaraman, Pallab Kanti Haldar, Himangshu Sekhar Maji, Asis Bala
Pharmacological heat-shock protein inducers and chemical chaperones inhibit upregulation of interleukin-8 by oxidized phospholipids
- Open Access
- Original Article
Klara Hellauer, Olga V. Oskolkova, Bernd Gesslbauer, Valery Bochkov
Suprabasin-derived polypeptides: SBSN(50-63) induces inflammatory response via TLR4-mediated mast cell activation
- Original Article
Tong Zhou, Xueshan Du, Lei Zhang, Yi Zheng, Tao Jia, Xiangjin Song, Delu Che, Songmei Geng
Diosmin nanocrystal gel alleviates imiquimod-induced psoriasis in rats via modulating TLR7,8/NF-κB/micro RNA-31, AKT/mTOR/P70S6K milieu, and Tregs/Th17 balance
- Open Access
- Original Article
Yasmine Shahine, Sarah A. Abd El-Aal, Ahmed M. Reda, Eman Sheta, Nouran M. Atia, Ossama Y. Abdallah, Sherihan Salaheldin Abdelhamid Ibrahim
Impact of protocatechuic acid on alleviation of pulmonary damage induced by cyclophosphamide targeting peroxisome proliferator activator receptor, silent information regulator type-1, and fork head box protein in rats
- Open Access
- Original Article
Abeer Salama, Rania Elgohary, Mohamed M. Amin, Sahar Abd Elwahab
Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin
- Original Article
Manar M. El Tabaa, Maram M. El Tabaa, Rehab M. Elgharabawy, Walaa G. Abdelhamid
Human TFF2-Fc fusion protein alleviates DSS-induced ulcerative colitis in C57BL/6 mice by promoting intestinal epithelial cells repair and inhibiting macrophage inflammation
- Original Article
Meng Guo, Rongrong Wang, Jiajia Geng, Zhen Li, Mingfei Liu, Xuxiu Lu, Jianteng Wei, Ming Liu
Jasminum humile (Linn) ameliorates CCl4-induced oxidative stress by regulating ER stress, inflammatory, and fibrosis markers in rats
- Original Article
Mehreen Fatima, Muhammad Rashid Khan
Phenolic acids-rich fraction from Ficus drupacea leaves for the prevention and treatment of ethanol-induced gastric mucosal injury in rats
- Open Access
- Original Article
Sherien M. Bakry, Asmaa F. Aboul Naser, Sabri I. El Negoumy, Mona E. S. Kassem, Essam Abdel-Sattar, Meselhy R. Meselhy
Arabincoside B isolated from Caralluma arabica as a potential anti-pneumonitis in LPS mice model
- Open Access
- COVID-19
- Original Article
Riham A. El-Shiekh, Ghazal Nabil, Aya A. Shokry, Yasmine H. Ahmed, Othman S. S. Al-Hawshabi, Essam Abdel-Sattar
Protective effects of curcumin and Ginkgo biloba extract combination on a new model of Alzheimer’s disease
- Open Access
- Original Article
Abdel-Azim Assi, Magda M. Y. Farrag, Dalia M. Badary, Essmat A. H. Allam, Mariam A. Nicola
Neuroprotective effect of tangeretin against chromium-induced acute brain injury in rats: targeting Nrf2 signaling pathway, inflammatory mediators, and apoptosis
- Open Access
- Original Article
Ahmed A. Sedik, Rania Elgohary
Melatonin suppresses inflammation and blood‒brain barrier disruption in rats with vascular dementia possibly by activating the SIRT1/PGC-1α/PPARγ signaling pathway
- Original Article
Phakkawat Thangwong, Pranglada Jearjaroen, Chainarong Tocharus, Piyarat Govitrapong, Jiraporn Tocharus
Potential effects of carbon monoxide donor and its nanoparticles on experimentally induced gastric ulcer in rats
- Open Access
- Original Article
Alaa E. Elsisi, Esraa F. Mekky, Sally E. Abu-Risha
Chrysophanol exerts a protective effect against Aβ25-35-induced Alzheimer’s disease model through regulating the ROS/TXNIP/NLRP3 pathway
- Original Article
Meng Zhang, Zhi-xian Ding, Wei Huang, Jing Luo, Shu Ye, Sheng-lin Hu, Peng Zhou, Biao Cai
In vitro and in vivo assessment of the anti-inflammatory activity of olive leaf extract in rats
- Open Access
- Original Article
Nada Fayez, Waleed Khalil, Essam Abdel-Sattar, Abdel-Fattah Mohamed Abdel-Fattah
Biseugenol from Ocotea cymbarum (Lauraceae) attenuates inflammation, angiogenesis and collagen deposition of sponge-induced fibrovascular tissue in mice
- Original Article
Bruno Antonio Ferreira, Francyelle Borges Rosa de Moura, Kaio Souza Gomes, Dalete Christine da Silva Souza, João Henrique Ghilardi Lago, Fernanda de Assis Araújo
Citral protects against LPS-induced endometritis by inhibiting ferroptosis through activating Nrf2 signaling pathway
- Original Article
Weiliang Zhao, Junrong Wang, Yang Li, Cong Ye
