Ausgabe 4/2025
Inhalt (35 Artikel)
Pharmacological modes of plant-derived compounds for targeting inflammation in rheumatoid arthritis: A comprehensive review on immunomodulatory perspective
- Review
Laiba Nazakat, Shaukat Ali, Muhammad Summer, Fakiha Nazakat, Shehzeen Noor, Anfah Riaz
Targeting mTOR with curcumin: therapeutic implications for complex diseases
- Review
Danial Khayatan, Seyed Mehrad Razavi, Zahra Najafi Arab, Hadis Nasoori, Abtin Fouladi, Aytak Vahdat Khajeh Pasha, Alexandra E. Butler, Sercan Karav, Saeideh Momtaz, Amir Hossein Abdolghaffari, Amirhossein Sahebkar
Emerging treatments for dermatologic diseases in infants, children, and adolescents: a systematic review of clinical trials on biologics and small molecule inhibitors
- Review
Alireza Jafarzadeh, Elham Behrangi, Mina Khosravi, Saba Falakeh, Jasmine Khalilnejad Amiri, Azadeh Goodarzi
Therapeutic applications of natural products in the management of venous diseases: a comprehensive review
- Open Access
- Review
Rasha E. Mostafa, Dalia E. Ali, Riham A. El-Shiekh, Ahmed N. El-Alfy, Mohamed S. Abd El Hafeez, Ahmed M. Reda, Nesrin M. Fayek
Orientin: a comprehensive review of a promising bioactive flavonoid
- Open Access
- Review
Mohamed I. Fahmy, Mohamed A. Sadek, Kareem Abdou, Ahmed M. El-Dessouki, Riham A. El-Shiekh, Samar S. Khalaf
NLRP3 inflammasomes pathway: a key target for Metformin
- Review
Yasamin Hosseini, Amirhossein Niknejad, Ayeh Sabbagh Kashani, Mahsa Gholami, Mahtab Roustaie, Mohammad Mohammadi, Saeideh Momtaz, Stephen L. Atkin, Tannaz Jamialahmadi, Amir Hossein Abdolghaffari, Amirhossein Sahebkar
The efficacy, safety, and persistence of vedolizumab versus adalimumab in patients with inflammatory bowel disease: a systematic review and meta-analysis
- Review
Zhixin Chen, Huo Li, Zhongzhuan Li, Rong Ouyang, Shijiang Huang, Shufen Qin, Jing Qin, Jiean Huang
Ceramide: a central regulator in Alzheimer’s disease pathogenesis
- Review
Priyanka Choudhary, Shilpa Kumari, Kajal Bagri, Rahul Deshmukh
Interplay between PI3k/AKT signaling and caspase pathway in Alzheimer disease: mechanism and therapeutic implications
- Review
Vandana Bhatia, Vir Vikram, Anjali Chandel, Aditya Rattan
Diverse role of S100 calcium-binding protein B in alzheimer’s disease: pathological mechanisms and therapeutic implications
- Review
Sampriti Sarkar, Pratyush Porel, Sourabh Kosey, Khadga Raj Aran
Insulin resistance in Alzheimer's disease: signalling mechanisms and therapeutics strategies
- Review
Mini Dahiya, Monu Yadav, Chetan Goyal, Anil Kumar
Innovative nanocarriers in arthritis therapy: the role of herbal cubosomes
- Review
Kajal Chaudhary, Lubhan Singh, Pallavi Dinanath Rai
Bacillus subtilis (NMCC-path-14) ameliorates acute phase of arthritis via modulating NF-κB and Nrf-2 signaling in mice model
- Original Article
Muhammad Usama Mazhar, Sadaf Naz, Tayyaba Zulfiqar, Jehan Zeb Khan, Fahim Hilal, Shakira Ghazanfar, Muhammad Khalid Tipu
Use quercetin for pulmonary fibrosis: a preclinical systematic review and meta-analysis
- Original Article
Xuanyu Wu, Xiang Xiao, Yuchen Su, Yuwei Zhang, Ganggang Li, Fei Wang, Quanyu Du, Han Yang
Therapeutic efficacy of zoledronic acid combined with calcium and calcitriol in the treatment of senile osteoporosis in elderly patients
- Original Article
Yi Zhang, Yuan Tian, Xiaojun Chen
Jasminum humile extract mitigates carrageenan-induced paw oedema in rats by modulating inflammatory and antioxidant signalling pathways
- Original Article
Mehreen Fatima, Lamya Ahmed Al-Keridis, Mohd Adnan, Nawaf Alshammari, Abdel Moneim Elhadi Sulieman, Muhammad Rashid Khan
Immunomodulatory properties of a methanolic extract of Ficus lyrata mitigate inflammation in Complete Freund’s Adjuvant-induced arthritis
- Original Article
Anam Iftikhar, Mohammad Saleem, Syed Atif Raza, Adrian Achuthan, Rodney Luwor, Taha Muhammad, Umair Majeed
Casticin reduces rosacea-related inflammation by inhibiting mast cell activation via Mas-related G protein-coupled receptor X2
- Original Article
Tao Jia, Yifan Xia, Mengyao Yi, Xinyue Zhang, Yi Zheng, Delu Che
Vanillic acid ameliorates collagen-induced arthritis by suppressing the inflammation response via inhibition of the MAPK and NF-κB signaling pathways
- Open Access
- Original Article
Yu Zhou, Pengfei Li, Zhongwen Zhi, Rong Chen, Chenghai Li, Chunbing Zhang
Nuclear receptor 4A1 inhibits chondrocyte inflammation and cartilage degeneration in osteoarthritis by inhibiting NF-κB signal pathway
- Original Article
Yawei Zhang, Hengheng Zheng, Baitong Li
Efficacy of Aster chinensis aerial parts metabolites in BALB/c mice model of Imiquimod-induced psoriasis skin inflammation
- Open Access
- Original Article
Mai S. Hendawy, Mona M. Hashem, Ahmed A. Zaki, Mostafa A. Rabie, Nesrine S. El Sayed, Riham Salah El Dine, Ali M. El-Halawany
Sodium hyaluronate and acupotomy bone decompression alleviates inflammatory responses in patients with knee osteoarthritis
- Original Article
Jia Wu, Qiong Tang, Xiaofei Tan
Treatment with cyclosporine attenuates the inflammatory process and severity of bisphosphonate-induced osteonecrosis of the jaws in rats
- Original Article
Camila Costa Dias, Caio Ferreira Freire Caetano, Gabriella Alves Julião Costa, Antônio Alexandre Coelho, José Vitor Mota Lemos, Dayrine Silveira de Paula, Juliana Paiva Marques Lima, Paulo Goberlânio de Barros Silva
Unravelling the prophylactic anti-inflammatory potential of Koenigia tortuosa through modulation of cytokine levels and inflammatory markers in LPS-induced localized inflammation in Wistar rat models
- Original Article
Ambreena Farooq, Mudasar Nabi, Khalid Bashir Dar, Syed Ishfa Andrabi, Nuzhat Khursheed, Farhat Jabeen, Showkat Ahmad Dar, Aijaz Hassan Ganie, Abdul Wajid Bhat, Showkat Ahmad Ganie
Unveiling the neuroprotective potential of Ipomoea carnea ethanol extract via the modulation of tau and β-secretase pathways in AlCl3-induced memory impairment in rats in relation to its phytochemical profiling
- Open Access
- Original Article
Walaa A. El-Kashak, Ahmed F. Essa, Mohamed F. Abdelhameed, Yasmine H. Ahmed, Asmaa S. Abd Elkarim, Mai M. Elghonemy, Bassant M. M. Ibrahim, Ahmed H. Gaara, Tahia K. Mohamed, Abdelsamed I. Elshamy
Kirenol ameliorates endotoxin-induced acute lung injury by inhibiting the ERK and JNK phosphorylation–mediated NFκB pathway in mice
- Original Article
Frank Cheau-Feng Lin, Shih-Pin Chen, Sheng-Chien Lin, Ching-Chi Tseng, Stella Chin-Shaw Tsai, Yu-Hsiang Kuan
Modulation of the cognitive impairment associated with Alzheimer’s disease by valproic acid: possible drug repurposing
- Open Access
- Original Article
Mirna Ezzat Sedrak Sorial, Ragwa Mansour Abdelghany, Nesrine Salah El Dine El Sayed
Gallic acid enhances memory, learning and reduces neuroinflammation in a rat model of scopolamine-induced cholinergic dysfunction
- Original Article
Mahbobe Alikhanzade, Maryam Khosravi, Mahmoud Hosseini, Arezoo Rajabian
The action of injectable nanodispersion of Bixa orellana (Chronic-in®) on arthritis in diabetic rats: pharmacological and histopathological studies
- Original Article
Lauana Gomes, Helison de Oliveira Carvalho, Gisele Rocha Lopes, Gabriel da Costa Furtado, Danna Emanuelle Santos Gonçalves, Nayara Nilcia Dias Colares, Adriana Maciel Ferreira, Crislany da Costa Furtado, Heitor Ribeiro da Silva, Abrahão Victor Tavares de L.T. dos Santos, Aline Lopes do Nascimento, Tamiris Marques Lage, Irma Danielle Rodrigues Pedro, Thiago Afonso Teixeira, José Carlos Tavares Carvalho
Neuroprotective efficacy of berberine and caffeine against rotenone‐induced neuroinflammatory and oxidative disturbances associated with Parkinson’s disease via inhibiting α-synuclein aggregation and boosting dopamine release
- Open Access
- Original Article
Tasnim S. Waheeb, Mohammad A. Abdulkader, Doaa A. Ghareeb, Mohamed E. Moustafa
Targeting TGF-β/VEGF/NF-κB inflammatory pathway using the Polyphenols of Echinacea purpurea (L.) Moench to enhance wound healing in a rat model
- Open Access
- Original Article
Marwa I. Ezzat, Mai M. Abdelhafez, Asmaa K. Al-Mokaddem, Shahira M. Ezzat
Curcumol attenuates hyperproliferation and inflammatory response in a psoriatic HaCaT keratinocyte model by inhibiting the PI3K-Akt pathway and ameliorates skin lesions and inflammatory status in psoriasis-like mice
- Original Article
Mutian Niu, Xiaolong Li, Mingzhao Li, Fangru Chen, Hui Cao, Qingbo Liu, Bin Liang, Guangyu Pan, Chengqin Liang, Jintao Gao
Therapeutic effect of formononetin in 6-OHDA induced Parkinson disease in rats
- Original Article
Tanvi Dayanand Pingale, Girdhari Lal Gupta
Editorial expression of concern: Chemomodulatory effect Melastoma Malabathricum Linn against chemically induced renal carcinogenesis rats via attenuation of inflammation, oxidative stress, and early markers of tumor expansion
- Editorial Expression of Concern
Amita Verma, Prakash Chandra Bhatt, Gaurav kaithwas, Nikunj Sethi, Mohd Rashid, Yashwant Singh, Mahfoozur Rahman, Fahad Al-Abbasi, Firoz Anwar, Vikas Kumar
