Ausgabe 5/2025
Inhalt (38 Artikel)
Flavonoids and flavonoid-based nanoparticles for the treatment of arthritis
- Review
Sanchit Dhankhar, Jatin Kumar, Samrat Chauhan, Ishrat Zahoor, Shahid Nazir Wani, Monika Saini, Jamila Akter Borsha, Sabina Yasmin, Mohammad Yousuf Ansari
Role of guanylate-binding protein 5 in inflammatory diseases, immune diseases, cancers, and its potential therapeutic implications
- Review
Xufan Sun, Guiyuan Jin, Huihui Zhou, Yan Wang, Fengxian Dai, Guangxi Zhou
Flavonoids regulating NLRP3 inflammasome: a promising approach in alleviating diabetic peripheral neuropathy
- Open Access
- Review
Saumya Khanna, Sachindra Kumar, Pratyasha Sharma, Rajni Daksh, Krishnadas Nandakumar, Rekha Raghuveer Shenoy
Role of polyphenolics in the management of rheumatoid arthritis through intracellular signaling pathways: a mechanistic review
- Review
Uzma Saleem, Maryam Farrukh, Malik Saadullah, Rida Siddique, Humaira Gul, Aqsa Ahmad, Bushra Shaukat, Muhammad Ajmal Shah
Microbial imbalance in the gut: a new frontier in Rheumatoid arthritis research
- Review
Rufaida Wasim, Sumaiya, Asad Ahmad, Aamir Anwar, Aimen Salman
From bench to bedside: exploring curcumin-driven signaling pathways in immune cells for cancer management
- Review
Pouya Goleij, Aryan Rezaee, Hiu Yan Lam, Mohammad Amin Khazeei Tabari, Noureldeen Ouf, Dorsa Alijanzadeh, Pantea Majma Sanaye, Danaé S. Larsen, Maria Daglia, Haroon Khan, Gautam Sethi, Alan Prem Kumar
Deciphering the role of cell signaling pathways in gout pathogenesis and the therapeutic potential of phytoconstituents in their modulation
- Review
Hrithik Dey, Syed Salman Ali, Vandana Arora Sethi
Dose-dependent effects of omega-3 polyunsaturated fatty acids on C-reactive protein concentrations in cardiometabolic disorders: a dose–response meta-analysis of randomized clinical trials
- Review
Manoochehr Amin Amlashi, Atefeh Payahoo, Saber Jafari Maskouni, Elaheh Dehghani, Mahtab Karami Talandashti, Yeganeh Ghelichi, Mahya Nikoumanesh, Soroush Rezvani, Hossein Shahinfar, Farzad Shidfar
Can pyridoxine function as an anti-pyroptosis agent? A narrative review
- Review
Astari Pranindya Sari, Reviono, Agus Dwi Susanto, Dono Indarto
The role of Ergothioneine in cognition and age-related neurodegenerative disease: a systematic review
- Review
Nurfarah Hazwani Takhor, Chia Wei Phan
Systematic review of comparative studies on emerging psoriasis treatments: comparing biologics with biologics, small molecule inhibitors with small molecule inhibitors, and biologics with small molecule inhibitors
- Review
Seyed Iraj Azimi, Alireza Jafarzadeh, Azadeh Goodarzi
Molecular mechanisms and treatment strategies for estrogen deficiency-related and glucocorticoid-induced osteoporosis: a comprehensive review
- Review
Satyajit Mohanty, Anwesha Sahu, Tuhin Mukherjee, Sneha Kispotta, Payel Mal, Muskan Gupta, Jeet Kumar Ghosh, Pranav Kumar Prabhakar
A comprehensive review on anti-inflammatory plants: a mechanistic insight through preclinical and clinical studies
- Review
Deepti Chaudhary, Saraswati Patel, Ritika Gururani, Pooja Chak, Sonika Jain, Jaya Dwivedi, Swapnil Sharma
Multifaceted roles of melatonin in oncology: an insight into its therapeutic potential in cancer management
- Review
Hossein Maghsoudi, Farhad Sheikhnia, Nooshin Hajmalek, Fatemeh Dadash Gholipour, Shahriar Alipour, Mansour Ghorbanpour, Sara Farzanegan, Seyed Mostafa Mir, Mohammad Yousef Memar
NSAID-encapsulated nanoparticles as a targeted therapeutic platform for modulating chronic inflammation and inhibiting cancer progression: a review
- Review
Srivarshini Sankar, Bharathi Kalidass, Janani Indrakumar, Gothandam Kodiveri Muthukaliannan
From receptor to response: dissecting the TLR4 pathway in diabetic neuropathy
- Review
Monserrat Hernandez-Reyes, Thura Tun Oo
Impact of NSAIDs corticosteroids DMARDs biologics and their comparisons with natural products in C-reactive proteins (CRP) linked cardiovascular disorders
- Review
Trilochan Satapathy, Anjali Minj, Mansi Verma
Gut microbiota and Parkinson’s Disease: a new frontier in understanding neurological health
- Review
Nishchhal Kumari, Veeranjaneyulu Addepalli, Aniket More, Ashwani Patil, Meghraj Suryawanshi
Exploring the anti-anaphylaxis potential of natural products: A Review
- Open Access
- Review
Aya H. Eid, Eman S. Zaki, Miral O. Sabry, Riham A. El-Shiekh, Samar S. Khalaf
Biomarkers in Alzheimer’s disease: new frontiers with olfactory models
- Review
Shubhrat Maheshwari, Aditya Singh, Amita Verma
Impact of corticoid receptors on Alzheimer’s disease: a neuroendocrine perspective
- Review
Falguni Goel, Daksh Kumar, Anushka Sharma
Exploring the therapeutic potential of NLRP3 inhibitors in Parkinson's Disease: a systematic review of in-vivo studies
- Review
Najwane Said Sadier, Inaam Ali Hazimeh, Walaa Khazaal, Amani Al Khayat Al Sabouri, Abdulmajeed G. Almutary, Abdullah M. Alnuqaydan, Linda Abou-Abbas
Comparative efficacy of pharmacologic interventions in ulcerative colitis: a network meta analysis
- Open Access
- Review
Atta Ullah Khan, Maria Ali, Muhammad Aamir Wahab
Ropivacaine effect on hemostasis and pain level in patients undergoing orthognathic surgery: a triple-blinded, randomized, clinical trial
- Original Article
Majid Hosseini-Abrishami, Mozhgan Kazemian, Mohammad Javad Sedaghati, Mohammad Alipour, Melika Hoseinzadeh, Alireza Ghaffarian-Hosseini, Vahid Reza Askari
Correction: Ropivacaine effect on hemostasis and pain level in patients undergoing orthognathic surgery: a triple-blinded, randomized, clinical trial
- Correction
Majid Hosseini-Abrishami, Mozhgan Kazemian, Mohammad Javad Sedaghati, Mohammad Alipour, Melika Hoseinzade, Alireza Ghaffarian-Hosseini, Vahid Reza Askari
3,4-Dihydroxybenzoic acid methyl ester from Vespa velutina auraria Smith against rheumatoid arthritis via modulating the apoptosis and inflammation through NF-κB pathway
- Original Article
Yi-Hao Che, Chao-He Liu, Xiu-Qin Pang, Heng Liu, Zhi-Bin Yang, Jia-Peng Wang, Huai Xiao
The association between anti-inflammatory therapies and renal outcomes in patients with established cardiovascular disease or high cardiovascular risks: a meta-analysis of randomised controlled trials
- Original Article
Wenfeng Yang, Zonglin Li, Chu Lin, Xiaoling Cai, Fang Lv, Wenjia Yang, Linong Ji
Amelioration of pain and adjuvant-induced arthritis by syringic acid via modulation of behavioral parameters and inflammatory mediators i.e. TNF-α, Interleukins, MCP-1, NF-kB and COX-2
- Original Article
Noviara Saleem, Syed Atif Raza, Alamgeer, Muhammad Khalil-ur-Rehman, Rukhsana Anwar, Abrar Ahmed, Hafiz Muhammad Irfan
Targeting TREM-1 receptors with metformin and pravastatin modulate monosodium iodoacetate-induced osteoarthritis
- Open Access
- Original Article
Eman R. Al Sawy, Mona M. Saber, Noha N. Nassar, Nesrine S. El Sayed
Endotoxin (lipopolysaccharide)-induced inflammation in albino rat and macrophages (RAW 264.7): Piper mullesua leaf extract as promising therapeutic against inflammatory pathophysiology via SOCS1 activation and phospho-NF-κB/JAK1/STAT1 inhibition
- Original Article
Rikraj Loying, Laikangbam Lamyanba, Anupriya Borah, Reparani Thokchom, Vekuno Cukhamu, Hiranmoy Barman, Bhaben Sharmah, Nazim Uddin Afzal, Mir Ekbal Kabir, Archana Moni Das, Jatin Kalita, Pulok Kumar Mukherjee, Nanaocha Sharma, Prasenjit Manna
The presumable combined effects of hydroxychloroquine and its metabolites on the blood lipids and glucose in the treatment of rheumatoid arthritis
- Open Access
- Original Article
Huaixuan Zhang, Xueting Wu, Yue Wang, Zhongling Yang, Yaqian Dai, Zongwen Shuai
Ocimene mitigates pyroptosis through TLR4/NLRP3-mediated mechanisms in CFA-induced inflammation
- Original Article
Iqra Laraib, Sumera Qasim, Ambreen Malik Uttra, Shaimaa R. Ahmed
A pharmaco-metabolomics study of Glycyrrhiza glabra, Boswellia sarca, and Acacia nilotica in acute allergic dermatitis
- Open Access
- Original Article
Bassant M. M. Ibrahim, A. F. Yousuf, M. M. El-Shawwa, Mona A. Mohammed
Role of TRPV1+ and TRPA1+ nociceptive neurons in delayed-onset muscle soreness: inhibition by hesperidin methyl chalcone
- Original Article
Giovana B. Cortez, Mariana M. Bertozzi, Amanda M. Dionisio, Maiara Piva, Nayara R. Morelli, Thacyana T. Carvalho, Rubia Casagrande, Waldiceu A. Verri Jr, Sergio M. Borghi
Tetramethylpyrazine alleviates hepatic fibrosis induced by experimental mansonic schistosomiasis
- Original Article
Ana Carolina Campos dos Santos, Daniel Figueiredo-Vanzan, Josiane Bentes, Juliana Maria Motta, Hilton Antônio Mata-Santos, Alexandre dos Santos Pyrrho, Morgana Teixeira Lima Castelo-Branco
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury
- Original Article
Gajendra N. Pardeshi, Noor Ali, Kamini R. Shirasath, Sameer N. Goyal, Kartik T. Nakhate, Sanjay N. Awathale
Calprotectin inhibition attenuates silica-induced lung fibrosis
- Original Article
Narjes Saheb Sharif-Askari, Bushra Mdkhana, Shirin Hafezi, Ola Faisal Elamin, Mariam Wed Eladham, Baraa Khalid Salah Al-Sheakly, Hala Halwani, Fatemeh Saheb Sharif-Askari, Rabih Halwani
Effective management of concomitant rheumatoid arthritis and T-large granular lymphocyte leukemia using reduced-dose upadacitinib
- Short Communication
Angelo Nigro