Ausgabe 6/2024
Inhalt (27 Artikel)
Leukotriene signaling in neurodegeneration: implications for treatment strategies
- Review
Veerta Sharma, Prateek Sharma, Thakur Gurjeet Singh
The role of quercetin in NLRP3-associated inflammation
- Review
Jiaqi Wu, Tongtong Lv, Yu Liu, Yifan Liu, Yukun Han, Xin Liu, Xiaochun Peng, Fengru Tang, Jun Cai
Essential oils: a potential alternative with promising active ingredients for pharmaceutical formulations in chronic wound management
- Review
Pulukkunadu Thekkeveedu Roshni, Punchappady Devasya Rekha
Vitamin D: A key player in COVID-19 immunity and lessons from the pandemic to combat immune-evasive variants
- Open Access
- Review
Hussein Sabit, Shaimaa Abdel-Ghany, Mahmoud S. Abdallah, Osama Abul-Maaty, Ahmed I. Khoder, Nabil A. Shoman, Mohamed Sameh Farrag, Pavel Martasek, Ayman M. Noreddin, Mahmoud Nazih
Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
- Review
Shiva Singh, Anuradha Mishra, Alka
Atheroprotective role of vinpocetine: an old drug with new indication
- Open Access
- Review
Mohammed H. Abu-Alghayth, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Athanasios Alexiou, Marios Papadakis, Mostafa M. Bahaa, Mohammed Afifi, Ammar AL-Farga, Eman Wahsh, Gaber El-Saber Batiha
Preoperative versus postoperative nonsteroidal anti-inflammatory drugs in femoroacetabular impingement patients undergoing hip arthroscopy surgery: analgesic effect, joint function, patients’ satisfaction, and quality of life
- Original Article
Zhiyuan Guo, Guangfei Liu, Weibin Li, Shouliang Lu, Ye Zhao, Lu Wang, Cai Cheng
Conventional DMARDs therapy decreases disease activity and inflammation in newly diagnosed patients with rheumatoid arthritis by increasing FoxP3, Sema-3A, and Nrp-1 gene expression
- Original Article
Parviz Soufivand, Ghazal Hosseini Torshizi, Seyed Askar Roghani, Mohammad Dastbaz, Ramin Lotfi, Bijan Soleymani, Fatemeh Heydarpour, Zahra Abdan, Hosna Allahyari
The role of traditional NSAIDs and selective COX-2 inhibitors on COVID-19 outcomes: a real-world data study
- Open Access
- Original Article
Narmeen Mallah, Irene Visos-Varela, Bahi Takkouche, Rosendo Bugarín-González, María Piñeiro-Lamas, Teresa Herdeiro, Maruxa Zapata-Cachafeiro, Almudena Rodríguez-Fernández, Angel Salgado-Barreira, Adolfo Figueiras, Eduardo Carracedo-Martínez, Rosa M. García-Álvarez, Francisco J. González-Barcala, Teresa M Herdeiro, Martina Lema-Oreiro, Samuel Pintos-Rodríguez, Maria Piñeiro-Lamas, Manuel Portela-Romero, Angela Prieto-Campo, Almudena Rodriguez-Fernández, Marc Saez, Margarita Taracido-Trunk
Glucocorticoid treatment during COVID-19 infection: does it affect the incidence of long COVID?
- Original Article
Polina Specktor, Dana Hadar, Hilla Cohen
Genetic proxies for therapy of insulin drug targets and risk of osteoarthritis: a drug-target Mendelian randomization analysis
- Open Access
- Original Article
Ziqin Cao, Qiangxiang Li, Jianhuang Wu, Yajia Li
Repurposing celecoxib as adjuvant therapy in patients with Parkinsonian disease: a new therapeutic dawn: randomized controlled pilot study
- Original Article
Mohannad O. Khrieba, Sahar K. Hegazy, Wessam Mustafa, Sahar M. El‑Haggar
On the origin of cysteamine-induced duodenal cytotoxicity and type II ferroptosis
- Short Communication
John V. Schloss, Sandor Szabo
A medicine and food homology formula prevents cognitive deficits by inhibiting neuroinflammation and oxidative stress via activating AEA–Trpv1–Nrf2 pathway
- Original Article
Ming-Jie Li, Jing-Yi Xu, Hua-Yue Zhang, Min Guo, Meng-Ning Lan, Jie Kong, Shi-Wei Liu, Hua-Jun Zheng
β-Citronellol: a potential anti-inflammatory and gastro-protective agent-mechanistic insights into its modulatory effects on COX-II, 5-LOX, eNOS, and ICAM-1 pathways through in vitro, in vivo, in silico, and network pharmacology studies
- Open Access
- Original Article
Urooj Iqbal, Abdul Malik, Nabeela Tabassum Sial, Malik Hassan Mehmood, Shoaib Nawaz, Marios Papadakis, Dalia Fouad, Hayam Ateyya, Nermeen N. Welson, Athanasios Alexiou, Gaber El-Saber Batiha
Anti-arthritic studies of ethnomedicine Gaultheria trichophylla Royle extract and salicylate-rich fraction using complete Freud’s adjuvant-induced rats: molecular docking and network pharmacology analysis
- Original Article
Fiaz Alam, Abrar Ahmad, Khalid Rauf, Abdulhakeem S. Alamri, Walaa F. Alsanie
Efficacy and safety of 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1, 2-benzothiazin-3-carboxamide 1,1-dioxide, a rapid-acting meloxicam formulation, for analgesia after orthopaedic surgery under general anaesthesia: a randomized controlled trial
- Original Article
Yingyong Zhou, Yan Jiang, Kaiming Duan, Qiongcan Li, Mengchang Yang, Qing Lei, Mingsheng Bao, Guijie Xie, Jie Sun, Liang Chen, Hongmei Zhou, Yanzhuo Zhang, Yidan Huang, Yuanli Gao, Liu Han, Han Lin, Yafeng Zhang, Yongquan Chen, Ling Zhao, Shuangtao Chen, Chun Chen, Haitao Jiang, Jinghua Ren, Wen Ouyang, Shaowen Tang, Saiying Wang
Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways
- Original Article
Helia Aghamiri, Afrooz Mohammadgholi-Beiki, Rojin Rashidian, Manijeh Motevalian, Parvaneh Rahimi-Moghaddam, Mohammad Sheibani, Majid Jafari-Sabet
Opuntia ficus-indica cladodes extract inhibits human neutrophil pro-inflammatory functions and protects rats from acetic acid-induced ulcerative colitis
- Original Article
Wafa Ferjani, Ahmed Kouki, Pham My-Chan Dang, Hamadi Fetoui, Yassine Chtourou, Néziha Ghanem-Boughanmi, Mossadok Ben-Attia, Jamel El-Benna, Abdelaziz Souli
Protective effect of freeze-dried extract of Persicaria bistorta Samp. on acetic acid-induced colitis model in rats: Involvement of nitric oxide and opioid system
- Original Article
Niusha Esmaealzadeh, Amirhossein Abdolghaffari, Maryam Baeeri, Maede Hasanpour, Mehrdad Iranshahi, Cristina Santarcangelo, Mahdi Gholami, Roodabeh Bahramsoltani
Combinatorial intervention with dental pulp stem cells and sulfasalazine in a rat model of ulcerative colitis
- Open Access
- Original Article
Riham M. Aly, Rehab S. Abohashem, Hanaa H. Ahmed, Alyaa S. Abdel Halim
Tocilizumab unfolds colo-protective and immunomodulatory effect in experimentally induced ulcerative colitis via mitigating autophagy and ER stress signaling
- Open Access
- Original Article
Omnia A. Younes, Doaa M. Elsherbiny, Diana M. F. Hanna, Amany M. Gad, Samar S. Azab
Hydrogel encapsulating gold nanoparticles for targeted delivery of nitroglycerin to reduce post-cardiac dysfunction inflammation by inhibiting the Wnt/β-catenin signaling pathway
- Original Article
Ruixuan Li, Aixia Xu, Ye Chen, Yihui Li, Ru Fu, Weihong Jiang, Xiaogang Li
Identification of JAZF1, KNOP1, and PLEKHA1 as causally associated genes and drug targets for Alzheimer’s disease: a summary data-based Mendelian randomization study
- Original Article
Yuhan Zhai, Ning Li, Yujie Zhang, Haibin Li, Lijuan Wu, Cuibai Wei, Jianguang Ji, Deqiang Zheng
Neuroprotective efficiency of celecoxib vesicular bilosomes for the management of lipopolysaccharide-induced Alzheimer in mice employing 23 full factorial design
- Open Access
- Original Article
Asmaa Badawy Darwish, Abeer Salama, Mostafa Mohammed Younis
Preclinical efficacy of oral and nasal rivastigmine-loaded chitosan nano-particles on AlCl3-induced Alzheimer’s-like disease in rats
- Open Access
- Original Article
Dina E. ElMosbah, Marwa S. Khattab, Marwa A. Ibrahim, Mona I. El-Asssal, Hala M. F. El Miniawy
Chemical composition and studying the possible neuroprotective effect of iridoids-rich fraction from Pentas lanceolata leaves using rotenone model of Parkinson’s disease in mice
- Open Access
- Original Article
Ahmed H. Afifi, Heba-Tollah M. Sweelam, Marwa E. El-Shamarka, Hisham A. Orban, Wessam H. Elesawy, Maki Nagata, Kuniyoshi Shimizu, Howaida I. Abd-Alla
