Ausgabe 6/2025
Inhalt (40 Artikel)
PDE4 inhibitors in psoriasis therapy: current insights and future directions
- Review
Amit Sharma, Niyati Pandoh, Keerti Dayal, Aditya Raj, Kirandeep Kaur, Navjot Kaur Sandhu, Vineet Kumar Rai, Shubham Thakur, Balak Das Kurmi
Paracetamol: the potential therapeutic pathways defining its clinical use
- Review
Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Eman M. Abd El-maksoud, Mustafa M. Shokr, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha
Protecting vascular health: the role of flavonoids during pregnancy complications in mitigating the risk of vascular dementia later in life
- Review
Ankita Sharma, Aman Jyoti, Prasad Rasane, Jyoti Singh
Exploring the efficacy of plant-based nutraceuticals in managing diabetic neuropathy
- Open Access
- Review
Samea Khan, Maria Markoulli, Amy T. Tsoi, Mark Willcox
Targeting the JAK/STAT3/SOCS signaling pathway in Alzheimer’s disease
- Review
Hayder M. Al-kuraishy, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Hebatallah M. Saad, Ali I. Al-Gareeb, Ali K. Albuhadily
Bioactive compound nanoparticles for Alzheimer's disease
- Review
Neha Kshirsagar, Ashwani Patil, Meghraj Suryawanshi
Role of mGluR7 in Alzheimer’s disease: pathophysiological insights and therapeutic approaches
- Review
Garry Hunjan, Khadga Raj Aran
Decoding the role of glucocorticoid-regulated kinase 1 in Alzheimer's disease: a promising path toward novel therapeutic strategies
- Review
Yukti Mittal, Pankaj Kumar, Kajal Joshi, Khadga Raj Aran
The therapeutic mechanisms of quercetin on inflammatory diseases: an update
- Review
Jie Xu, Haikun Hu, Haixu Jiang, Qiuzhu Wei, Honglin Zhang, Qingyi Lu
Carica papaya in health and disease: a review of its bioactive compounds for treating various disease conditions, including anti-inflammatory and anti-arthritic activities
- Review
Md. Khokon Miah Akanda, A. H. M. Nazmul Hasan, Sanzia Mehjabin, G. M. Masud Parvez, Sabina Yasmin, Md. Sayeed Akhtar, Saistha Anjum, Sumel Ashique, Rokeya Sulatana, Mohammad Yousuf Ansari
Farnesol alleviates inflammatory responses and oxidative stress in Freund’s complete adjuvant induced arthritic rat model and associated risk factors of atherosclerosis
- Original Article
Isma Anwar, Ali Sharif, Mushtaq Ahmad, Maryam Shabbir, Bushra Akhtar
Amelioration of Freund’s adjuvant-induced polyarthritis by Diosmin-loaded nanoparticles in Wistar rats; a mechanistic study
- Original Article
Hamna Mehmood, Ammara Saleem, Muhammad Furqan Akhtar, Aisha Mobashar
N-Dimethyl chalcone facilitated augmentation of IL-10 and diminution of TNF-α, IL-1β, IL-6, NFκB, and COX-2 in FCA-induced arthritic rat model
- Original Article
Faiza Waseem, Ali Sharif, Maryam Shabbir, Bushra Akhtar, Syed Wadood Ali Shah, Shahnaz, Adeel Arshad, Ejaz Basheer, Muhammad Asif Hanif, Muhammad Ali
Nimesulide and sodium hyaluronate ameliorate the inflammatory process and pain severity in traumatic knee osteoarthritis
- Original Article
Wei Wang, Yao Du, Xiaohe Zhang
Cassia fistula fruit pulp extracts mitigate collagen-induced arthritis via regulation of oxidative stress and inflammation
- Original Article
Aashcharya U. Mishra, Sumati Sen, Mridula Sahu, Meenu Devi, Dewasya P. Singh, Aakriti Gupta, Abhishek K. Rai, Ratnasekhar Ch, Ashutosh K. Shukla, Dnyaneshwar U. Bawankule, Daya N. Mani
Dapagliflozin targets the crosstalk between apoptosis, autophagy, and Hedgehog signaling pathways through AMPK activation in the adjuvant-induced arthritic rat model
- Open Access
- Original Article
Aya A. El-Demerdash, Samar F. Darwish, Marwa O. El-Derany, Ebtehal El-Demerdash
Ipomoea carnea Jacq. ameliorates formalin-induced paw inflammation in rats through modulation of oxidative and inflammatory pathways
- Original Article
Shabab Nasir, Muhammad Usman, Humaira Gul, Malik Saadullah, Maryam Farrukh, Rida Siddique, Bushra Shaukat, Abdullah R. Alanzi, Ana Sanches Silva, Muhammad Ajmal Shah
Anti-arthritic potential and mechanistic insights of methanol extract of Rhamnus prinoides Engl. in complete Freund’s adjuvant-induced rats
- Original Article
James Kimani Kamau, Mathew Piero Ngugi, Joseph N. Ngeranwa
Phytochemical studies of Gerbera jamesonii and evaluation of anti-inflammatory potential in formaldehyde-induced arthritis in rats
- Original Article
Malik Saad Ullah, Ateeq Amjad, Zunera Chauhdary, Uzma Saleem, Naheed Akhtar
Phytofabricated Farsetia aegyptia-derived silver nanoparticles mediate antibacterial and wound-healing activities in diabetic foot infection rat model
- Original Article
Enas M. Ali, Peramaiyan Rajendran, Basem M. Abdallah
Phytochemical analysis of leaf extract of Piper nigrum and investigation of its biological activities
- Original Article
Pankaj Barman, Srija Hazarika, Kallol Roy, Ravindra K. Rawal, Rituraj Konwar
Full-spectrum Cannabis sativa extract enhances gut-peripheral organ integrity after experimental ischemic stroke
- Original Article
Solange de Souza Stork, Khiany Mathias, Fernanda Gava, Larissa Joaquim, David dos Santos, Anita Dal Bó Tiscoski, Sandra Bonfante, Yasmin Ribeiro Strickert, Richard Simon Machado, Helena Mafra Martins, Jéssica Schaefer Chaves, Jaqueline Generoso, Lucineia Gainski Danielski, Amanda Della Giustina, Rahisa Scussel, Rafael Bitencourt, Josiel Mileno Mack, Mariana Pereira de Souza Goldim, Ricardo Andrez Machado-de-Ávila, Tatiana Barichello, Franciane Bobinski, Fabricia Petronilho
Repurposing of high-dose N-acetylcysteine as anti-inflammatory, antioxidant and neuroprotective agent in moderate to severe traumatic brain injury patients: a randomized controlled trial
- Open Access
- Original Article
Alaa Refaat Gouda, Noha A El-Bassiouny, Ahmad Salahuddin, Emad Hamdy Hamouda, Amira B. Kassem
Voclosporin promotes neurological function recovery by inhibiting inflammation and maintaining blood–brain barrier integrity following rtPA reperfusion after MCAO in mice
- Original Article
Yangmin Zheng, Shubei Ma, Wei Sun, Feng Yan, Yumin Luo
The neuroprotective potential of Gerbera Jamesonii in a neuronal demyelination rat model through the modulation of interleukins, cyclooxygenase and tumor necrosis factor-α
- Original Article
Shazia Anwer Bukhari, Haleema Sadia, Zunera Chauhdary
Carnosol mitigates Ang II-stimulated vascular injury and oxidative stress by directly binding to FAK and inhibiting its activation
- Original Article
Yucheng Jiang, Zhaozheng Zheng, JunYi Wang, Yingjie Liao, Zhihan Jia, Wante Lin, Diyun Xu, Jiong Wang, Gaojun Wu, Guang Liang, Bozhi Ye
Bioactive potential of Tripleurospermum inodorum with detailed insight into anti-inflammatory activity through in vitro, in vivo evaluations and network pharmacology
- Original Article
Marija Ivanov, Aleksandra Popov Aleksandrov, Jelena Božunović, Maria Inês Dias, Ricardo C. Calhelha, Jelena Kulaš, Lillian Barros, Isabel C. F. R. Ferreira, Dejan Stojković
Evaluation of anti-inflammatory and anti-oxidant properties of Anacardium occidentale leaf
- Original Article
Eleazar Chukwuemeka Anorue, Parker Elijah Joshua, Onyinyechi Chinwedu Asogwa
Naproxen and prednisolone reduced intestinal alteration and permeability and bacterial translocation in rat adjuvant-induced arthritis
- Original Article
Sophie Hecquet, Perle Totoson, Hélène Martin, Philippe Saas, Jean-Paul Pais-de-Barros, Maude Tournier, Clément Prati, Daniel Wendling, Céline Demougeot, Frank Verhoeven
Unveiling the neuroprotective potential of Jatropha humboldtiana leaves and its metabolic profiling by UPLC-MS/MS
- Original Article
Paul Alan Arkin Alvarado-García, Marilú Roxana Soto-Vásquez, Ricardo D. D. G. de Albuquerque, Fadia S. Youssef, Reem M. Diri, Mohamed L. Ashour
Camellia nitidissima Chi extract ameliorates dextran sulfate sodium-induced acute ulcerative colitis in mice by inhibiting TLR4/NF-κB-mediated inflammatory activation
- Original Article
Lirong Li, Rui Huang, Wenwen Li, Dengjie Yao, Beibei Zhang, Mengna Li, Shunan Luo, Yu Qin, Wenwen Zhang
Iota-carrageenan oligosaccharide ameliorates DSS-induced colitis in mice by mediating gut microbiota dysbiosis and modulating SCFAs-PI3K-AKT pathway
- Original Article
Meixian Xiang, Songtao Wu, Minxin Liu, Bin Zhang, Xiankun Xia, Wenjing Tan, Shijian Xiang
Chaperone-mediated autophagy, heat shock protein 70, and serotonin: novel targets of beta-hydroxybutyrate in HFFD/LPS-induced sporadic Alzheimer’s disease model
- Open Access
- Original Article
Reem A. Mohamed, Dalaal M. Abdallah, Hanan S. El-Abhar
Empagliflozin and memantine combination ameliorates cognitive impairment in scopolamine + heavy metal mixture-induced Alzheimer’s disease in rats: role of AMPK/mTOR, BDNF, BACE-1, neuroinflammation, and oxidative stress
- Open Access
- Original Article
Ebtsam S. Abdel-lah, Hoda S. Sherkawy, Wafaa H. Mohamed, Mariam A. Fawy, Asmaa A. Hasan, Asmaa A. Muhammed, Amira F. Taha, Abeer A. Tony, Nashwa Hamad, Marwa G. Gamea
Clinical study evaluating the efficacy and safety of Cilostazol as an adjuvant therapy to methotrexate on patients with rheumatoid arthritis
- Open Access
- Original Article
Samar M. Eldadamony, Sahar M. El-Haggar, Abdel Moaty A. Ali, Tarek M. Mostafa
Correction to: Anti-arthritic and immunomodulatory efficacy of Micromeria biflora Benth extract and its fractions in rats by restoring oxidative stress, metalloproteinases, pro-inflammatory and anti-inflammatory cytokines network
- Correction
Fakhria A. Al-Joufi, Ambreen Malik Uttra, Sumera Qasim, Urooj Iqbal, Nabeela Tabassum Sial, Noura M. Alhumaid
Correction: Exploration of molecular interactions responsible for anti-inflammatory attributes of GI friendly micro-sized formulation of flurbiprofen and clove oil
- Correction
Hafiz Muhammad Zubair, Mohamed Farouk Elsadek, Sajid Asghar, Khalid S. Al-Numair, Malik Saadullah, Shafqat Rasul Chaudhry, Thomas Efferth, Muhammad Asif
Correction: Vitamin D: a key player in COVID‑19 immunity and lessons from the pandemic to combat immune‑evasive variants
- Open Access
- Correction
Hussein Sabit, Shaimaa Abdel-Ghany, Mahmoud S. Abdallah, Osama Abul-Maaty, Ahmed I. Khoder, Nabil A. Shoman, Mohamed Sameh Farrag, Pavel Martasek, Ayman M. Noreddin, Mahmoud Nazih
Correction: The impact of tocilizumab treatment on the severity of inflammation and survival rates in sepsis is significantly influence by the timing of administration
- Open Access
- Correction
Taha Tavaci, Zekai Halici, Elif Cadirci, Mustafa Ozkaraca, Kamber Kasali
Retraction Note: Exploring the therapeutic potential of Anastatica hierochuntica essential oil in DSS-induced colitis
- Retraction Note
Abdelrahim Alqudah, Esam Qnais, Omar Gammoh, Yousra Bseiso, Mohammed Wedyan, Mohammed Alqudah, Muna Oqal, Rawan Abudalo, Shtaywy S. Abdalla
