Ausgabe 9/2025
Inhalt (48 Artikel)
The potential role of carvedilol in COVID-19 management: perspective and take-away
- Review
Hayder M. Al-Kuraishy, Maii A. Abdelnaby, Marios Papadakis, Athanasios Alexiou, Gaber El-Saber Batiha
MicroRNAs in SARS-CoV-2 infection: emerging modulators of inflammation, pathogenesis, and therapeutic potential
- Review
Mohammad Fayyad-Kazan
COVID-19 in comorbid chronic diseased patients, pregnant and lactating women: pathophysiology, available drug treatment, and the most suitable protocol regimen in each group
- Review
Hend M. Mohamed, Yara Y. Elkholy, Yara M. Mokhtar, Mirna A. Orady, Heba Sh. Elmetwaly, Hend Mo. Abdelwahab, Yasmeen S. Abdelrady, Mohamed M. Elgohary, Mohamed Kh. Elmahdy
Immuno-nutritional therapy in experimental autoimmune encephalomyelitis: a translational pathway to multiple sclerosis management
- Review
Mansur Aliyu, Ali Akbar Saboor-Yaraghi, Muhammad Ibrahim Getso, Fatema Tuz Zohora
Recent advances in the therapeutics and modes of action of a range of agents used to treat ulcerative colitis and related inflammatory conditions
- Review
Alka Patel, Parag Jain, Ajazuddin
Parkinson’s disease: genetics and neuroinflammatory insights
- Review
Isha Chandel, Shilpa Kumari, Kajal Bagri, Amit Bhatia, Rahul Deshmukh
Therapeutic potential of luteolin in neurodegenerative disorders: targeting Nrf2, NFĸB, MAPK, and JAK-STAT pathways to combat neuroinflammation and apoptosis
- Review
Koleshwar Mahto, Omkar Kumar Kuwar, Aayushi Maloo, Nileshwar Kalia
The link between oral health and neurodegeneration: a review of periodontitis in Alzheimer’s and Parkinson’s disease and dementia
- Review
Pooja Wagaskar, Sayali Gaikwad, Meghraj Suryawanshi, Ashwani Patil
The renin–angiotensin system (RAS) and arthritic diseases: therapeutic potential for RAS inhibitors
- Review
Yasser H. Habib, Mahmoud Khattab, Mennatallah A. Gowayed
Efficacy and safety of celecoxib in schizophrenia: a systematic review and meta-analysis of randomized controlled trials
- Open Access
- Review
NourAllah Farag, Abdullah Selim, Osama Hassan, Hamdy A. Makhlouf, Mahmoud Soliman, Lamees Taman, Omar Kassar
Effects of Nigella sativa and its constituents on inflammatory markers in ovalbumin-induced asthma model: a preclinical systematic review and meta-analysis
- Review
Hassan Ghobadi, Elmira Mohammadzadeh, Mohammad Reza Aslani
Therapeutic potential of Boswellia serrata in arthritis management: mechanistic insights into COX-2, 5-LOX, and NFĸB modulation
- Review
Koleshwar Mahto, Omkar Kumar Kuwar, Aayushi Maloo, Abhishek Kumar
A systematic review of natural products targeting Nrf2-Keap1-ARE pathway and their influence on neurodegenerative disorders
- Review
Sharmila Gote, Sonal Dubey, Shachindra L. Nargund, Shankar Thapa
Unlocking therapeutic potential in traumatic brain injury: exploring microenvironmental targets, signaling pathways and translational hurdles
- Review
Deepankar Bahuguna, Etikala Amulya, Shristi Arya, Soham Loharkar, Ganesh Vambhurkar, Saptarshee Bhattacharjee, Dinesh Kumar Chandanapalli, Jitender Madan, Saurabh Srivastava
Pharmacotherapeutic potential of daidzein: insights into mechanisms and clinical relevance
- Review
Chinchu Praisthy LJ, Ravi Kushwah, Sachin Dubey, Vipin Kumar, Smita Jain
Transforming advancing autosomal dominant polycystic kidney disease care: investigating new horizons in treatment and research
- Review
Komal Thapa, Heena Khan, Amarjot Kaur, Thakur Gurjeet Singh
The protective effects of coenzyme Q10 on blood pressure: a narrative review of anti-inflammatory and antioxidant mechanisms
- Review
Seyed Mohammad Hosseini Roknabadi, Amirmohammad Abolhassani, Erfan Davoodi, Fatemeh Zahra Moghaddam Rad, Sadegh Jafarnejad
Unlocking the molecular pathway of atopic dermatitis: journey so far and roads ahead
- Review
Sourabh Kumar, Rohit Sharma, Kumari Komal, Dinesh Kumar, Rashmi Ghosh, Manish Kumar
The IL-12 family cytokines in neurodegenerative diseases: dual roles in neurotoxicity and neuroprotection
- Review
Pouya Goleij, Alireza Amini, Pantea Majma Sanaye, Mohammad Mahdi Heidari, Mohammad Amin Khazeei Tabari, Michael Aschner, Danaé S. Larsen, Haroon Khan, Maria Daglia
Regulation of toll-like receptor signaling pathways in age-related eye disease: from mechanisms to targeted therapeutics
- Review
Qiaoqiao Kong, Yixiang Jiang, Xiang Li, Xuejing Lu
Modulation of inflammatory and oxidative stress pathways by polyphenol-rich Pleurospermum candollei extract in carrageenan-induced paw edema in rats
- Original Article
Mehreen Fatima, Muhammad Rashid Khan, Motrih Al-Mutiry, Mitesh Patel, Nawaf Alshammari, Mohd Adnan
Anti-IBD activity of Eleusine indica through inhibition of TNF-alpha and p38 MAPK expression
- Original Article
Otomo Ohene-Bekoe, Michael Hagan, Kofi Oduro Yeboah, Bernard Elikplim Petershie, Aaron Opoku Antwi, Newman Osafo
Intra-articular hexagonal boron nitride–hyaluronic acid composite hydrogels rebalance cytokine profiles and enhance extracellular matrix regeneration in a rabbit osteoarthritis model
- Original Article
Ezgi Kar, Fatih Kar, Yapıncak Göncü, Gökçe Mehmet Ay, Aykut Küçükbaş, Cansu Özbayer, Dilek Burukoğlu Dönmez, Cansu Arslan, Hakan Şentürk, Nusret Köse, Nuran Ay
Protective effects of ozone therapy on cartilage degeneration in temporomandibular joint osteoarthritis
- Original Article
Tássia T. Machado, Ana Carolina S. Machado, Catarine M. Nishijima, Cleverton Roberto de Andrade, Sílvio Roberto Consonni, Lizandra M. de Sousa, Carlos A. Parada, Cláudia H. Tambeli
Mulberroside A ameliorates murine allergic airway inflammation by suppressing Th2 response and oxidative stress
- Original Article
Chian-Jiun Liou, Shu-Ju Wu, Shu-Chen Cheng, Wen-Chung Huang
Mitigation of inflammation and oxidative stress in FCA-induced arthritic rat model through gum acacia intervention: a comprehensive in‑vivo study
- Original Article
Sobia Khalid Awan, Ali Sharif, Bushra Akhtar
Orange peel extract and hesperidin attenuate myeloperoxidase activity and oxidative stress in vitro, with anti-inflammatory effects in vivo: a natural approach to gingival protection
- Original Article
Tinhinane Rekeb, Samia Bedouhene, Nassima Senani, Sahra-Amel Belambri, Meriem-Dehbia Chabane, Kahina Ladj, Riadh Ksouri, Pham My-Chan Dang, Jamel El Benna
Alphonsea elliptica (Hook.f. and Thomson) methanol leaves extract obliterates inflammatory processes in LPS-induced human plasma
- Open Access
- Original Article
Ali Attiq, Juriyati Jalil, Sheryar Afzal, Waqas Ahmad
Veratric acid and zinc: a synergistic approach to accelerated wound healing in rats
- Original Article
Rumila Afzal, Sidra Kaleem, Aslam Khan, Fareeha Anwar, Umair Ilyas, Alaa S. Alhegaili, Mansoor Ali, Sajid Ali
Sunitinib treatment reduces proinflammatory cytokine levels and mortality rates by suppressing the NLRP3 inflammasome signaling pathway in sepsis
- Original Article
Ahmet Kucuk, Nurhak Aksungur, Zekai Halici, Taha Tavaci, Mustafa Ozkaraca, Behzat Tebrizi
Cucurbitacin B alleviates DSS-induced experimental colitis by targeting ZNF70 to suppress the NLRP3/STAT3 signaling axis
- Original Article
Shen Cao, Yuhan Wang, Yi Tai, Jing Han, Yanjin Zheng, Can Wang, Hong Xiang Zuo, Ming Yue Li, Yue Xing, Xuejun Jin, Juan Ma
Longitudinal relationships between changes in post-COVID mental fatigue and neuropsychiatric symptoms across distinct recovery trajectories
- Open Access
- Original Article
Wenrui Bao, Siyuan Chen, Ningkun Hong, Gengchen Ye, Chiyin Li, Jingmei Xie, Peng Li, Heng Li, Yang Wang, Jixin Liu, Xuan Niu, Yuchen Zhang
A systems biology approach reveals dual neurotherapeutic mechanisms of Dioscorea bulbifera in Alzheimer’s disease via estrogen signaling and cholinergic modulation
- Original Article
Mayank Roy Chowdhury, Sudarshana Deepa Vijaykumar
Phytochemical studies of Veitchia arecina Becc. leaves with evaluation of in-vitro, in-vivo anti-inflammatory, and wound healing properties in rats
- Open Access
- Original Article
Radwa S. Emad, Rasha A. Attia, Mona Fekry, Nesreen M. I. M. Elkomy, Tarek M. Ibrahim, Amal A. Al-Gendy
Tectoridin modulates intertwined molecular pathways in metabolic syndrome: insights from network pharmacology, molecular docking, and in vivo studies
- Original Article
Ashwini Kumar Mishra, Pravat Kumar Sahoo, Rajesh Singh, Smita Jain
Therapeutic potential of alpha-lipoic acid on mitochondrial dynamics, oxidative/nitrosative stress, and histopathological changes in rat ulcerative colitis model
- Original Article
İrem Taner, Nur Banu Bal, Saadet Özen Akarca Dizakar, Veysel Bay, Mürşide Ayşe Demirel
The effects of ellagic acid in metabolic dysfunction-associated steatotic liver disease (MASLD) patients: a randomized, add-on, double-blind, controlled trial
- Original Article
Mohammad Mahmoudi Azar, Matin Shirazinia, Mohsen Nematy, Vafa Baradaran Rahimi, Motahare Bateni, Fateme Tafaghodi Piadeh Gheibi, Farnood Rajabzadeh, Ladan Goshayeshi, Sara Honari, Mehran Mottahedi, Vahid Reza Askari
Anti-inflammatory effects of 6-gingerol on arthritis in rats by inhibition of the NF-kB TAB1 signaling pathway
- Original Article
Xueming Yao, Qiuyi Wang, Xuemei Yuan, Feng Luo, Yi Ling, Changming Chen, Wukai Ma
Correction: Tetramethylpyrazine alleviates hepatic fibrosis induced by experimental mansonic schistosomiasis
- Correction
Ana Carolina Campos dos Santos, Daniel Figueiredo-Vanzan, Josiane Bentes, Juliana Maria Motta, Hilton Antônio Mata-Santos, Alexandre dos Santos Pyrrho, Morgana Teixeira Lima Castelo-Branco
Correction: Tectoridin modulates intertwined molecular pathways in metabolic syndrome: insights from network pharmacology, molecular docking, and in vivo studies
- Correction
Ashwini Kumar Mishra, Pravat Kumar Sahoo, Rajesh Singh, Smita Jain
Retraction Note: Anti-rheumatic activity of pseudoephedrine (a substituted phenethylamine) in complete Freund’s adjuvant-induced arthritic rats by down regulating IL-1β, IL-6 and TNF-α as well as upregulating IL-4 and IL-10
- Retraction Note
Haseeb Ahsan, Hafiz Muhammad Irfan, Alamgeer, Muhammad Shahzad, Mulazim Hussain Asim, Muhammad Akram, Muhammad Shoaib Zafar
Retraction Note: Effects of Chrysophyllum albidum fruit pulp on haemodynamic parameters, pro-inflammatory markers, antioxidant parameters and critical biomolecules associated with hypertension–in vivo
- Retraction Note
Folake Lucy Oyetayo, Seun Funmilola Akomolafe, Gbemisola Beulah Balogun
Retraction Note: Polystichum braunii extracts inhibit Complete Freund’s adjuvant-induced arthritis via upregulation of I-κB, IL-4, and IL-10, downregulation of COX-2, PGE2, IL-1β, IL-6, NF-κB, and TNF-α, and subsiding oxidative stress
- Retraction Note
Ammara Saleem, Mohammad Saleem, Muhammad Furqan Akhtar, Muhammad Shahzad, Shah Jahan
Retraction Note: Assessment of antiarthritic potential of Asparagus dumosus using formaldehyde and CFA-induced arthritic models in rats via modulation of oxidative stress biomarkers and mRNA expression of IL-1b, IL-6, RANKL, OPG, TNF-α and COX-2
- Retraction Note
Nimra Nazar, Malik Hassan Mehmood, Rida Siddique, Muhammad Naeem Faisal
Retraction Note: Novel glycoside from Wedelia calendulacea inhibits diethyl nitrosamine-induced renal cancer via downregulating the COX-2 and PEG2 through nuclear factor-κB pathway
- Retraction Note
Amita Verma, Bahar Ahmed, Firoz Anwar, Mahfoozur Rahman, Dinesh Kumar Patel, Gaurav Kaithwas, Ravi Rani, Prakash C. Bhatt, Vikas Kumar
Retraction Note: Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling
- Open Access
- Retraction Note
Mennatallah O. Zaki, S. El-Desouky, Doaa A. Elsherbiny, Mohamed Salama, Samar S. Azab
