Introduction
Methods
Study design
Procedures
Anthropometric assessment
12-Lead ECG
Echocardiographic assessment
Conventional 2D, Doppler and tissue Doppler measures
Speckle tracking echocardiography measures
Statistical analysis
Results
LD | MD | HD | |
---|---|---|---|
Sample (n) | 48 | 157 | 287 |
Age (Years) | 25 ± 3*† | 23 ± 4 | 23 ± 4 |
BSA (m2) | 1.9 ± 0.2 | 2.1 ± 0.2‡§ | 1.9 ± 0.2 |
Height (cm) | 1.8 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 |
Weight (kg) | 77 ± 15 | 94 ± 11‡§ | 77 ± 10 |
SBP (mmHg) | 131 ± 8 | 131 ± 9 | 128 ± 12 |
DBP (mmHg) | 73 ± 6* | 68 ± 7 | 70 ± 8 |
Heart Rate (bpm) | 66 ± 15*† | 57 ± 10 | 55 ± 10 |
Training (years) | 10 ± 6 | 13 ± 4 | 13 ± 6 |
Training (hours/week) | 21 ± 12 | 19 ± 8 | 17 ± 8 |
LD | MD | HD | |
---|---|---|---|
RVOT-PLAX (mm) | 30 ± 4 | 33 ± 5‡ | 32 ± 4 |
RVOT1 (mm) | 31 ± 4 | 35 ± 5‡§ | 33 ± 4 |
RVOT2 (mm) | 24 ± 3 | 26 ± 4‡§ | 26 ± 4ll |
RVD1 (mm) | 41 ± 5 | 44 ± 5‡ | 44 ± 5ll |
RVD2 (mm) | 31 ± 4 | 32 ± 5 | 31 ± 6 |
RVD3 (mm) | 87 ± 9 | 90 ± 11 | 90 ± 9 |
RVDA (cm2) | 24 ± 5 | 29 ± 4‡§ | 27 ± 5ll |
RVSA (cm2) | 13 ± 3 | 16 ± 3‡ | 15 ± 3ll |
RVWT (mm) | 3.7 ± 0.8 | 4.1 ± 0.8‡§ | 3.9 ± 0.9 |
RVOT-PLAX (mm/m2) | 16 ± 2 | 14 ± 4 | 16 ± 2¶ |
RVOT-PLAX (mm/(m2)0.5) | 21 ± 3 | 22 ± 5 | 23 ± 3ll¶ |
RVOT1 (mm/m2) | 16 ± 3 | 15 ± 4 | 17 ± 3¶ |
RVOT1 (mm/(m2)0.5) | 23 ± 3 | 23 ± 5 | 24 ± 3 |
RVOT2 (mm/m2) | 13 ± 2 | 12 ± 3 | 13 ± 2¶ |
RVOT2 (mm/(m2)0.5) | 17 ± 2 | 17 ± 4 | 19 ± 3ll¶ |
RVD1 (mm/m2) | 21 ± 3* | 19 ± 5 | 22 ± 3¶ |
RVD1 (mm/(m2)0.5) | 30 ± 3 | 29 ± 6 | 31 ± 3ll¶ |
RVD2 (mm/m2) | 16 ± 2* | 14 ± 4 | 16 ± 3¶ |
RVD2 (mm/(m2)0.5) | 22 ± 3 | 21 ± 5 | 22 ± 4 |
RVD3 (mm/m2) | 45 ± 6* | 39 ± 10 | 46 ± 5¶ |
RVD3 (mm/(m2)0.5) | 62 ± 6 | 59 ± 12 | 64 ± 7ll¶ |
RVDA (cm2/m2) | 12 ± 2 | 14 ± 2‡ | 14 ± 2ll |
RVSA (cm2/m2) | 7 ± 2 | 7 ± 1 | 8 ± 2ll |
LD | MD | HD | |
---|---|---|---|
TAPSE (mm) | 23 ± 5 | 24 ± 4 | 24 ± 4 |
RVFAC (%) | 46 ± 8 | 46 ± 8 | 45 ± 8 |
RVOT VTI (cm) | 19 ± 3 | 18 ± 3 | 20 ± 16 |
TDI S’ (cm/s) | 15 ± 3 | 15 ± 2 | 14 ± 2 |
TDI E′ (cm/s) | 15 ± 3 | 15 ± 3 | 15 ± 3 |
TDI A′ (cm/s) | 10 ± 3 | 10 ± 3 | 10 ± 3 |
Time to peak S′ (ms) | 183 ± 21 | 193 ± 23 | 190 ± 29 |
Time to Peak E′ (ms) | 509 ± 49 | 526 ± 45 | 522 ± 54 |
Peak ε (%) | − 23.4 ± 3.1 | − 22.7 ± 2.7 | − 23.5 ± 2.6 |
Time to Peak ε (s) | 0.37 ± 0.04 | 0.38 ± 0.03 | 0.38 ± 0.04 |
Peak SRS’ (l/s) | − 1.2 ± 0.2 | − 1.1 ± 0.2 | − 1.2 ± 0.2 |
Peak SRE′ (l/s) | 1.6 ± 0.3 | 1.5 ± 0.3 | 1.6 ± 0.3 |
Peak SRA′ (l/s) | 0.7 ± 0.2 | 0.8 ± 0.2 | 0.7 ± 0.2 |
LD | MD | HD | |
---|---|---|---|
Global | − 23.4 ± 3.1 | − 22 ± 5.2 | − 22.6 ± 5 |
Base to apex gradient ε (%) (lateral Wall) | 3.9 ± 8.5 | 2.8 ± 7.8 | 5.7 ± 7.5 |
Basal | − 26.4 ± 6.6 | − 26.4 ± 7.1 | − 25.9 ± 5.5 |
Mid | − 27.3 ± 4.8 | − 27.3 ± 5.4 | − 27.8 ± 4.2 |
Apical | − 30.9 ± 4.5 | − 28.7 ± 5 | − 31.4 ± 4.9¶ |
Base to apex gradient ε (%) (septal Wall) | − 5.6 ± 5.3* | − 0.4 ± 5.5 | − 3.2 ± 5.8¶ |
Apical | − 22.9 ± 4.5* | − 18.8 ± 4.8 | − 21.5 ± 4.7¶ |
Mid | − 18.3 ± 3.1 | − 17.8 ± 2.5 | − 17.6 ± 2.5 |
Basal | − 17.6 ± 2.7 | − 18.6 ± 2.7 | − 18 ± 3.1 |