The online version of this article (doi:10.1186/1471-2318-14-13) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests.
GRF, IBC and AMVC contributed to the conception and design of the study, analysis and interpretation of data, revising it critically for important intellectual content and final approval of the version to be submitted. ALN contributed to the design of the study. CCB, IL, KTM and MNJS contributed to the drafting of the article and revising it critically for important intellectual content. All authors read and approve the final manuscript.
The purpose of this study was to investigate the influence of muscle mass and bone mineral density on markers of mobility in dwelling elderly women.
This cross-sectional study included 99 elderly women, who were 65 years old or above, in Campinas-SP, Brazil. To collect data, we used sociodemographic data, the body mass index (BMI), health status, comorbidities, use of medications, mobility tests (TUG and gait speed) and examinations of the body composition (densitometry with dual-emission X-ray absorptiometry “DXA”). In order to examine the relationship between muscle and bone mass with mobility (gait speed and TUG), we applied the Spearman correlation coefficient.
Also was applied the analysis of covariance (ANCOVA) adjusted for age and comorbidities. To identify the factors associated with mobility, we used the univariate and multivariate logistic regression analysis. The level of significance for statistical tests was P < 0.05.
The correlation between sarcopenia and bone mineral density with mobility tests showed a significant relationship only between sarcopenia and TUG (r = 0.277, P = 0.006) in Spearman correlation coefficient. The result of the correlation analysis (ANCOVA) showed that sarcopenia was associated with gait speed (r2 = 0.0636, P = 0.0018) and TUG (r2 = 0.0898, P = 0.0027). The results of the multivariate analysis showed that age (P = 0.034, OR = 1.081) was associated with worse performance on gait speed. By highlighting the TUG test, the results of the multivariate analysis showed that the age (P = 0.004, OR = 1.111) and BMI in overweight (P = 0.011, OR = 7.83) and obese (P < 0.001, OR = 7.84) women were associated with lower performance of the functionality of the lower limbs.
The findings with regard to mobility tests which were analyzed in this study indicate the association of variables related to the aging process that contribute to the decline in physical performance, for example, age, BMI and sarcopenia.
Shin H, Panton LB, Button GR, Ilich JZ: Relationship of physical performance with body composition and bone mineral density in individuals over 60 years of age: a systematic review. J Aging Res. 2011, 23: 1-14. CrossRef
Thomas E, Croft PR, Dziedzic KS: Hand problems in community-dwelling older adults: onset and effect on global physical function over a 3-year period. Rheumatology (Oxford). 2009, 48: 183-187. CrossRef
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinková E, Vandewoude M, Zamboni M, European Working Group on Sarcopenia in Older People: Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people. Age Ageing. 2010, 39: 412-423. 10.1093/ageing/afq034. CrossRefPubMedPubMedCentral
World Health Organization: Global database on body mass index. BMI classification. URL: http://www.apps.who.int/bmi/index.jsp?introPage=intro_3.html
Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA, Cardiovascular Health Study Collaborative Research Group: Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001, 56: 146-156. 10.1093/gerona/56.3.M146. CrossRef
Hayes K, Johnson M: Measures of adult general performance tests. the berg balance scale, dynamic gait index (DGI), gait speed, physical performance test (PPT), timed chair stand test, timed up and go, and tinetti performance-oriented mobility assessment (POMA). Arthritis & Rheuma. 2003, 49: 28-42. 10.1002/art.11411. CrossRef
Aleman MH, Lee SY, Javed F, Thornton J, Heymsfield SB, Pierson RN, Pi Sunyer FX, Wang ZM, Wang J, Gallagher D: Elderly Mexicans have less muscle and greater total and truncal fat compared to African-Americans and Caucasians with the same BMI. J Nutr Health Aging. 2009, 13: 919-923. 10.1007/s12603-009-0252-1. CrossRef
- Influence of muscle mass and bone mass on the mobility of elderly women: an observational study
Gláucia R Falsarella
Ibsen B Coimbra
Caroline C Barcelos
Kedma T Montedori
Manuela NJ Santos
Anita L Neri
Arlete MV Coimbra
- BioMed Central
Neu im Fachgebiet Innere Medizin
Meistgelesene Bücher aus der Inneren Medizin
Mail Icon II