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Erschienen in: Urolithiasis 6/2008

01.12.2008 | Symposium Paper

Inhibition of crystallization of calcium oxalate by the extraction of Tamarix gallica L

verfasst von: Ahmed Bensatal, M. R. Ouahrani

Erschienen in: Urolithiasis | Ausgabe 6/2008

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Abstract

The main objective is to study the inhibitor effect of acid fraction of the extract of Tamarix gallica L on the crystallization of calcium oxalate. The extract of Tamarix gallica L is very rich by acid compounds that are used as an inhibitor of nephrolithiasis (calcium oxalate). Our study of the calcium oxalate crystallization is based on the model of turbidimetry by means of a spectrophotometer. The calcium oxalate formation is induced by the addition of oxalate solutions of sodium and of calcium chloride. The addition of inhibitor with various concentrations enabled us to give information on the percentage of inhibition. The comparison between the turbidimetric slopes with and without inhibitor gives the effectiveness of inhibitor for the acid fraction. By comparing the photographs of with and without inhibitor, we concluded that the extract of Tamarix gallica L acts at the stage of growth. The acid fraction of the extract of Tamarix gallica L gives an activity remarkable in the formation of urinary lithiasis (calcium oxalate); this effectiveness is due to the presence of functions of acid.
Literatur
8.
Zurück zum Zitat Doddametikurke RB, Chandra SB, Browning AJ, Cartledge JJ (2007) The role of urinary kidney stone inhibitors and promoters in the pathogenesis of calcium containing renal stones. Eau Ebu Update 5:126–136CrossRef Doddametikurke RB, Chandra SB, Browning AJ, Cartledge JJ (2007) The role of urinary kidney stone inhibitors and promoters in the pathogenesis of calcium containing renal stones. Eau Ebu Update 5:126–136CrossRef
9.
Zurück zum Zitat Sakly R, Chaouch A, Elhani A, Najjar MF (2003) Effects of intraperitoneally administered vitamin E and selenium on calcium oxalate renal stone formation: experimental study in rat. Ann Urol (Paris) 37:47–50. doi:10.1016/S0003-4401(03)00007-X Sakly R, Chaouch A, Elhani A, Najjar MF (2003) Effects of intraperitoneally administered vitamin E and selenium on calcium oxalate renal stone formation: experimental study in rat. Ann Urol (Paris) 37:47–50. doi:10.​1016/​S0003-4401(03)00007-X
10.
Zurück zum Zitat Hess B, Jordi S, Zipperle L, Ettinger E, Giovanoli R (2000) Citrate determines calcium oxalate crystallization kinetics and crystal morphology—studies in the presence of Tamm-Horsfall protein of a healthy subject and a severely recurrent calcium stone former. Nephrol Dial Transplant 15:366–374. doi:10.1093/ndt/15.3.366 PubMedCrossRef Hess B, Jordi S, Zipperle L, Ettinger E, Giovanoli R (2000) Citrate determines calcium oxalate crystallization kinetics and crystal morphology—studies in the presence of Tamm-Horsfall protein of a healthy subject and a severely recurrent calcium stone former. Nephrol Dial Transplant 15:366–374. doi:10.​1093/​ndt/​15.​3.​366 PubMedCrossRef
11.
Zurück zum Zitat Saravanan DM, Amzad H, Salman Z, Gam LH, Zhari I (2006) The use of principal component analysis and self-organizing map to monitor inhibition of calcium oxalate crystal growth by Orthosiphon stamineus extract. Chemom Intell Lab Syst 81:21–28. doi:10.1016/j.chemolab.2005.09.007 CrossRef Saravanan DM, Amzad H, Salman Z, Gam LH, Zhari I (2006) The use of principal component analysis and self-organizing map to monitor inhibition of calcium oxalate crystal growth by Orthosiphon stamineus extract. Chemom Intell Lab Syst 81:21–28. doi:10.​1016/​j.​chemolab.​2005.​09.​007 CrossRef
14.
Zurück zum Zitat Marcio EB, Roberta L, Lucildes PM, Jivaldo RM, Nestor S, Mirian AB (2006) Effect of extract of Phyllanthus niruri on crystal deposition in experimental urolithiasis. Urol Res 34:351–357. doi:10.1007/s00240-006-0065-1 CrossRef Marcio EB, Roberta L, Lucildes PM, Jivaldo RM, Nestor S, Mirian AB (2006) Effect of extract of Phyllanthus niruri on crystal deposition in experimental urolithiasis. Urol Res 34:351–357. doi:10.​1007/​s00240-006-0065-1 CrossRef
16.
Zurück zum Zitat Hennequin C, Lalanne V, Estepa L, Drueke T, Daudon M, Lacour B (1997) Validation by image analysis of a turbidimetric method to study calcium oxalate crystallization. Clin Nephrol 48(5):292–299PubMed Hennequin C, Lalanne V, Estepa L, Drueke T, Daudon M, Lacour B (1997) Validation by image analysis of a turbidimetric method to study calcium oxalate crystallization. Clin Nephrol 48(5):292–299PubMed
18.
Zurück zum Zitat Abdelkhalek O, Touhami M, Mbarki M (2005) In vitro and in vivo study of effect of lemon juice on urinary lithogenesis. Arch Esp Urol 58:1087–1092 Abdelkhalek O, Touhami M, Mbarki M (2005) In vitro and in vivo study of effect of lemon juice on urinary lithogenesis. Arch Esp Urol 58:1087–1092
19.
Zurück zum Zitat Suzuki K, Kawamura K, Tsugawa R (1999) Formation and growth inhibition of calcium oxalate by Takusha (Alisma Rhizoma). Scanning Microsc 13:183–189 Suzuki K, Kawamura K, Tsugawa R (1999) Formation and growth inhibition of calcium oxalate by Takusha (Alisma Rhizoma). Scanning Microsc 13:183–189
Metadaten
Titel
Inhibition of crystallization of calcium oxalate by the extraction of Tamarix gallica L
verfasst von
Ahmed Bensatal
M. R. Ouahrani
Publikationsdatum
01.12.2008
Verlag
Springer-Verlag
Erschienen in
Urolithiasis / Ausgabe 6/2008
Print ISSN: 2194-7228
Elektronische ISSN: 2194-7236
DOI
https://doi.org/10.1007/s00240-008-0157-1

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