Skip to main content
Erschienen in: Techniques in Coloproctology 3/2012

01.06.2012 | Original Article

Initial experience of treating anal fistula with the Surgisis anal fistula plug

verfasst von: S. Chan, J. McCullough, A. Schizas, P. Vasas, A. Engledow, A. Windsor, A. Williams, C. R. Cohen

Erschienen in: Techniques in Coloproctology | Ausgabe 3/2012

Einloggen, um Zugang zu erhalten

Abstract

Background

Complex anal fistulas remain a challenge for the colorectal surgeon. The anal fistula plug has been developed as a simple treatment for fistula-in-ano. We present and evaluate our experience with the Surgisis anal fistula plug from two centres.

Methods

Data were prospectively collected and analysed from consecutive patients undergoing insertion of a fistula plug between January 2007 and October 2009. Fistula plugs were inserted according to a standard protocol. Data collected included patient demographics, fistula characteristics and postoperative outcome.

Results

Forty-four patients underwent insertion of 62 plugs (27 males, mean age 45.6 years), 25 of whom had prior fistula surgery. Mean follow-up was 10.5 months Twenty-two patients (50%) had successful healing following the insertion of plug with an overall success rate of 23 out of 62 plugs inserted (35%). Nineteen out of 29 patients healed following first-time plug placement, whereas repeated plug placement was successful in 3 out of 15 patients (20%; p = 0.0097). There was a statistically significant difference in the healing rate between patients who had one or less operations prior to plug insertion (i.e. simple fistulas) compared with patients who needed multiple operations (18 out of 24 patients vs. 4 out of 20 patients; p = 0.0007).

Conclusions

Success of treatment with the Surgisis anal fistula plug relies on the eradication of sepsis prior to plug placement. Plugs inserted into simple tracts have a higher success rate, and recurrent insertion of plugs following previous plug failure is less likely to be successful. We suggest the fistula plug should remain a first-line treatment for primary surgery and simple tracts.
Literatur
1.
Zurück zum Zitat Whiteford MH, Kilkenny J 3rd, Hyman N (2005) Standards practice task force; American society of colon and rectal surgeons. Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised). Dis Colon Rectum 48:1337–1342PubMedCrossRef Whiteford MH, Kilkenny J 3rd, Hyman N (2005) Standards practice task force; American society of colon and rectal surgeons. Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised). Dis Colon Rectum 48:1337–1342PubMedCrossRef
2.
Zurück zum Zitat Hamalainen KP, Sainio AP (1997) Cutting seton for anal fistulas: high risk of minor control defects. Dis Colon Rectum 40:1443–1446PubMedCrossRef Hamalainen KP, Sainio AP (1997) Cutting seton for anal fistulas: high risk of minor control defects. Dis Colon Rectum 40:1443–1446PubMedCrossRef
3.
Zurück zum Zitat Isbister WH, Al Sanea N (2001) The cutting seton: an experience at King Faisal Specialist Hospital. Dis Colon Rectum 44:722–727PubMedCrossRef Isbister WH, Al Sanea N (2001) The cutting seton: an experience at King Faisal Specialist Hospital. Dis Colon Rectum 44:722–727PubMedCrossRef
4.
Zurück zum Zitat Graf W, Pahlman L, Ejerbald S (1995) Functional results after seton treatment of high transsphincteric anal fistulas. Eur J Surg 161:289–291PubMed Graf W, Pahlman L, Ejerbald S (1995) Functional results after seton treatment of high transsphincteric anal fistulas. Eur J Surg 161:289–291PubMed
5.
Zurück zum Zitat Ozuner G, Hull TL, Cartmill J, Fazio VW (1996) Long-term analysis of the use of transanal rectal advancement flaps for complicated anorectal/vaginal fistulas. Dis Colon Rectum 39:10–14PubMedCrossRef Ozuner G, Hull TL, Cartmill J, Fazio VW (1996) Long-term analysis of the use of transanal rectal advancement flaps for complicated anorectal/vaginal fistulas. Dis Colon Rectum 39:10–14PubMedCrossRef
6.
Zurück zum Zitat Tyler KM, Aarons CB, Sentovich SM (2007) Successful sphincter-sparing surgery for all anal fistulas. Dis Colon Rectum 50:1535–1539PubMedCrossRef Tyler KM, Aarons CB, Sentovich SM (2007) Successful sphincter-sparing surgery for all anal fistulas. Dis Colon Rectum 50:1535–1539PubMedCrossRef
7.
Zurück zum Zitat Loungnarath R, Dietz DW, Mutch MG, Birnbaum EH, Kodner IJ, Fleshman JW (2004) Fibrin glue treatment of complex anal fistulas has low success rate. Dis Colon Rectum 47:432–436PubMedCrossRef Loungnarath R, Dietz DW, Mutch MG, Birnbaum EH, Kodner IJ, Fleshman JW (2004) Fibrin glue treatment of complex anal fistulas has low success rate. Dis Colon Rectum 47:432–436PubMedCrossRef
8.
Zurück zum Zitat Cintron JR, Park JJ, Orsay CP (2000) Repair of fistula in ano using fibrin adhesive: long-term follow-up. Dis Colon Rectum 43:944–949PubMedCrossRef Cintron JR, Park JJ, Orsay CP (2000) Repair of fistula in ano using fibrin adhesive: long-term follow-up. Dis Colon Rectum 43:944–949PubMedCrossRef
9.
Zurück zum Zitat Johnson EK, Gaw JU, Armstrong DN (2006) Efficacy of anal fistula plug vs. fibrin glue in closure of anorectal fistulas. Dis Colon Rectum 49:371–376PubMedCrossRef Johnson EK, Gaw JU, Armstrong DN (2006) Efficacy of anal fistula plug vs. fibrin glue in closure of anorectal fistulas. Dis Colon Rectum 49:371–376PubMedCrossRef
10.
Zurück zum Zitat Haim N, Neufield D, Ziv Y (2011) Long- term results of fibrin glue treatment for cryptoglandular perianal fistulas: a multicentre study. Dis Colon Rectum 54:1279–1283PubMedCrossRef Haim N, Neufield D, Ziv Y (2011) Long- term results of fibrin glue treatment for cryptoglandular perianal fistulas: a multicentre study. Dis Colon Rectum 54:1279–1283PubMedCrossRef
11.
Zurück zum Zitat Lawes DA, Efron JE, Abbas M, Heppell J, Young-Fadok TM (2008) Early experience with the bioabsorbable anal fistula plug. World J Surg 32:1157–1159PubMedCrossRef Lawes DA, Efron JE, Abbas M, Heppell J, Young-Fadok TM (2008) Early experience with the bioabsorbable anal fistula plug. World J Surg 32:1157–1159PubMedCrossRef
12.
Zurück zum Zitat Christoforidis D, Etzioni DA, Goldberg SM, Madoff RD, Mellgren A (2008) Treatment of complex anal fistulas with the collagen fistula plug. Dis Colon Rectum 51:1482–1487PubMedCrossRef Christoforidis D, Etzioni DA, Goldberg SM, Madoff RD, Mellgren A (2008) Treatment of complex anal fistulas with the collagen fistula plug. Dis Colon Rectum 51:1482–1487PubMedCrossRef
13.
Zurück zum Zitat Echenique I, Mella JR, Rosado F, Echenique IA, Mella MT, Quevedo G (2008) Puerto Rico experience with plugs in the treatment of anal fistulas. Bol Asoc Med P R 100:8–12PubMed Echenique I, Mella JR, Rosado F, Echenique IA, Mella MT, Quevedo G (2008) Puerto Rico experience with plugs in the treatment of anal fistulas. Bol Asoc Med P R 100:8–12PubMed
14.
Zurück zum Zitat Garg P (2009) To determine the efficacy of anal fistula plug in the treatment of high fistula-in-ano: an initial experience. Colorectal Dis 11(6):588–591 Garg P (2009) To determine the efficacy of anal fistula plug in the treatment of high fistula-in-ano: an initial experience. Colorectal Dis 11(6):588–591
15.
Zurück zum Zitat Thekkinkattil D, Botterill I, Ambrose NS et al (2009) Efficacy of the anal fistula plug in complex anorectal fistulae. Colorectal Dis 11:584–587PubMedCrossRef Thekkinkattil D, Botterill I, Ambrose NS et al (2009) Efficacy of the anal fistula plug in complex anorectal fistulae. Colorectal Dis 11:584–587PubMedCrossRef
16.
Zurück zum Zitat Schwandner O, Stadler F, Dietl O, Wirsching RP, Fuerst A (2008) Initial experience on efficacy in closure of cryptoglandular and Crohn’s transsphincteric fistulas by the use of the anal fistula plug. Int J Colorectal Dis 23:319–324PubMedCrossRef Schwandner O, Stadler F, Dietl O, Wirsching RP, Fuerst A (2008) Initial experience on efficacy in closure of cryptoglandular and Crohn’s transsphincteric fistulas by the use of the anal fistula plug. Int J Colorectal Dis 23:319–324PubMedCrossRef
17.
Zurück zum Zitat Champagne BJ, O’Connor LM, Ferguson M, Orangio GR, Schertzer ME, Armstrong DN (2006) Efficacy of anal fistula plug in closure of cryptoglandular fistulas: long-term follow-up. Dis Colon Rectum 49:1817–1821PubMedCrossRef Champagne BJ, O’Connor LM, Ferguson M, Orangio GR, Schertzer ME, Armstrong DN (2006) Efficacy of anal fistula plug in closure of cryptoglandular fistulas: long-term follow-up. Dis Colon Rectum 49:1817–1821PubMedCrossRef
18.
Zurück zum Zitat Safar B, Jobanputra S, Sands D, Weiss E, Nogeuras J, Wexner SD (2009) Anal fistula plug: initial experience and outcomes. Dis Colon Rectum 52:248–252PubMedCrossRef Safar B, Jobanputra S, Sands D, Weiss E, Nogeuras J, Wexner SD (2009) Anal fistula plug: initial experience and outcomes. Dis Colon Rectum 52:248–252PubMedCrossRef
19.
Zurück zum Zitat Ortiz H, Marzo J, Ciga MA, Orteiza F, Armendariz P, de Miguel M (2009) Randomised clinical trial of anal fistula plugs versus endorectal advancement flap for the treatment of high cryptoglandular fistula in ano. Br J Surg 96:608–612PubMedCrossRef Ortiz H, Marzo J, Ciga MA, Orteiza F, Armendariz P, de Miguel M (2009) Randomised clinical trial of anal fistula plugs versus endorectal advancement flap for the treatment of high cryptoglandular fistula in ano. Br J Surg 96:608–612PubMedCrossRef
20.
Zurück zum Zitat Wang JY, Garcia-Aguilar J, Sternberg JA, Abel ME, Varma MG (2009) Treatment of transsphincteric anal fistulas: are fistula plugs an acceptable alternative? Dis Colon Rectum 52:692–697PubMedCrossRef Wang JY, Garcia-Aguilar J, Sternberg JA, Abel ME, Varma MG (2009) Treatment of transsphincteric anal fistulas: are fistula plugs an acceptable alternative? Dis Colon Rectum 52:692–697PubMedCrossRef
21.
Zurück zum Zitat Parks A, Stitz R (1976) Symposium: fistula-in-ano. The treatment of high fistula-in-ano. Dis Colon Rectum 19:487–499PubMedCrossRef Parks A, Stitz R (1976) Symposium: fistula-in-ano. The treatment of high fistula-in-ano. Dis Colon Rectum 19:487–499PubMedCrossRef
22.
Zurück zum Zitat Mizrahi N, Wexner SD, Zmora O et al (2002) Endorectal advancement flap: are there predictors of failure? Dis Colon Rectum 45:1616–1621PubMedCrossRef Mizrahi N, Wexner SD, Zmora O et al (2002) Endorectal advancement flap: are there predictors of failure? Dis Colon Rectum 45:1616–1621PubMedCrossRef
23.
Zurück zum Zitat Kodner IJ, Mazor A, Shemesh EI, Fry RD, Fleshman JW, Birnbaum EH (1993) Endorectal advancement flap repair of rectovaginal and other complicated anorectal fistulas. Surgery 114:682–689; discussion 689–690PubMed Kodner IJ, Mazor A, Shemesh EI, Fry RD, Fleshman JW, Birnbaum EH (1993) Endorectal advancement flap repair of rectovaginal and other complicated anorectal fistulas. Surgery 114:682–689; discussion 689–690PubMed
24.
Zurück zum Zitat Ellis CN (2007) Bioprosthetic plugs for complex anal fistulas: an early experience. J Surg Educ 64:36–40PubMedCrossRef Ellis CN (2007) Bioprosthetic plugs for complex anal fistulas: an early experience. J Surg Educ 64:36–40PubMedCrossRef
25.
Zurück zum Zitat Ky AJ, Sylla P, Steinhagen R, Steinhagen E, Khaitov S, Ly EK (2008) Collagen fistula plug for the treatment of anal fistulas. Dis Colon Rectum 51:838–843PubMedCrossRef Ky AJ, Sylla P, Steinhagen R, Steinhagen E, Khaitov S, Ly EK (2008) Collagen fistula plug for the treatment of anal fistulas. Dis Colon Rectum 51:838–843PubMedCrossRef
26.
Zurück zum Zitat Schwandner T, Roblick MH, Kierer W, Brom A, Padberg W, Hirschburger M (2009) Surgical treatment of complex anal fistulas with the anal fistula plug: a prospective multicenter study. Dis Colon Rectum 52:1578–1583PubMedCrossRef Schwandner T, Roblick MH, Kierer W, Brom A, Padberg W, Hirschburger M (2009) Surgical treatment of complex anal fistulas with the anal fistula plug: a prospective multicenter study. Dis Colon Rectum 52:1578–1583PubMedCrossRef
27.
Zurück zum Zitat Lunniss PJ, Sheffield JP, Talbot IC, Thomson JP, Phillips RK (1995) Persistence of idiopathic anal fistula may be related to epithelialization. Br J Surg 82:32–33PubMedCrossRef Lunniss PJ, Sheffield JP, Talbot IC, Thomson JP, Phillips RK (1995) Persistence of idiopathic anal fistula may be related to epithelialization. Br J Surg 82:32–33PubMedCrossRef
28.
Zurück zum Zitat Van Kopperen PJ, ten Kate FJ, Bemelman WA, Slors JF (2010) Histological identification of epithelium in perianal fistulae: a prospective study. Colorectal Dis 12:891–895CrossRef Van Kopperen PJ, ten Kate FJ, Bemelman WA, Slors JF (2010) Histological identification of epithelium in perianal fistulae: a prospective study. Colorectal Dis 12:891–895CrossRef
29.
Zurück zum Zitat McGee MF, Champagne BJ, Stulberg JJ, Reynolds H, Marderstein E, Delaney CP (2010) Tract length predicts successful closure with anal fistula in cryptoglandular fistulas. Dis Colon Rectum 53:1116–1120PubMedCrossRef McGee MF, Champagne BJ, Stulberg JJ, Reynolds H, Marderstein E, Delaney CP (2010) Tract length predicts successful closure with anal fistula in cryptoglandular fistulas. Dis Colon Rectum 53:1116–1120PubMedCrossRef
Metadaten
Titel
Initial experience of treating anal fistula with the Surgisis anal fistula plug
verfasst von
S. Chan
J. McCullough
A. Schizas
P. Vasas
A. Engledow
A. Windsor
A. Williams
C. R. Cohen
Publikationsdatum
01.06.2012
Verlag
Springer Milan
Erschienen in
Techniques in Coloproctology / Ausgabe 3/2012
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-012-0810-0

Weitere Artikel der Ausgabe 3/2012

Techniques in Coloproctology 3/2012 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.