Erschienen in:
14.01.2019 | Letter to the Editor
Injury of the prefronto-caudate tract in a patient with apathy following intracerebral hemorrhage in the caudate nucleus
verfasst von:
Sung Ho Jang, Seong Ho Kim, Hyeok Gyu Kwon
Erschienen in:
Acta Neurologica Belgica
|
Ausgabe 1/2019
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Excerpt
The caudate nucleus (CN), as a part of the basal ganglia, interconnects with the prefrontal cortex (PFC), temporal cortex, frontal eye field, and cerebellum. These connections are involved in motor and cognitive functions [
1]. Specifically, the prefronto-caudate tract is involved in apathy, anxiety, depression, and disinhibition [
2]. Apathy is classically defined as a lack of feeling, emotion, interest and concern, and clinically presents as the absence of motivation, voluntary movement or speech [
3]. Injury of the CN, PFC, or the prefronto-caudate tract in particular, connected to the medial PFC, and orbitofrontal cortex (OFC) is related to apathy [
4,
5]. …