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24.02.2018 | Original Article | Ausgabe 4/2018

Comparative Clinical Pathology 4/2018

Innate immunological responses of Asian sea bass, Lates calcarifer (Bloch, 1790) for experimentally challenged Aeromonas hydrophila infection

Zeitschrift:
Comparative Clinical Pathology > Ausgabe 4/2018
Autoren:
Palani Kathirkaman, Gopalakrishnan Ayyaru, Muhil Vannan Serelathan, Vijayapoopathi Singaravel, Thangaraj Gunasekaran

Abstract

Modulation of innate immunity was determined in the Aeromonas hydrophila-challenged Asain sea bass, Lates calcarifer. The haemato-immunological parameters were studied in blood serum. Blood was sampled at 3, 6, 12, and 24th h post-challenged infection and control. Histopathological examination of most important organs (ventral musculature tissue, kidney and liver) was studied in the infected fish. The present study results indicated that at early stages of infection, TEC, Hb, PCV, MCV, MCH, and MCHC were not altered significantly, whereas in TLC, the values were fluctuated. Lysozyme, NBT, and protein were significantly increased (P < 0.05) at all the respective time periods than the control. Histopathological results of infected tissues revealed that the myofibrillar necrosis, congested blood vessels, large-sized melano-macrophage with hyper-cellular activity.

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