Erschienen in:
01.11.2010 | Review article
Insulin autoimmune syndrome (Hirata disease): epidemiology in Asia, including Japan
verfasst von:
Yasuko Uchigata, Yukimasa Hirata, Yasuhiko Iwamoto
Erschienen in:
Diabetology International
|
Ausgabe 1/2010
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Abstract
As populations with a higher prevalence of HLADRB1*0406 have been found to have a higher risk of developing insulin autoimmune syndrome (IAS), we report here the clinical features of Asian and Japanese IAS. There was female dominance in the 20- to 49-year-old age group at the onset of IAS development. Forty-two percent of Japanese IAS patients had received drugs or α-lipoic acid containing the sulfhydryl group, while 81% of Asian IAS patients outside Japan had received methimazole or carbimazole before the development of IAS.