Intensive Care Medicine 9/2020

Systematic Review

Pain management during the withholding and withdrawal of life support in critically ill patients at the end-of-life: a systematic review and meta-analysis

Andres Laserna, Alejandro Durán-Crane, María A. López-Olivo, John A. Cuenca, Cosmo Fowler, Diana Paola Díaz, Yenny R. Cardenas, Catherine Urso, Keara O’Connell, Clara Fowler, Kristen J. Price, Charles L. Sprung, Joseph L. Nates

Original

Hypertonic saline for fluid resuscitation in ICU patients post-cardiac surgery (HERACLES): a double-blind randomized controlled clinical trial

Carmen A. Pfortmueller, Manuel Kindler, Noelle Schenk, Anna S. Messmer, Benjamin Hess, Laura Jakob, Stefanie Wenger, Jan Waskowski, Patrick Zuercher, Frederik Stoehr, Stephan M. Jakob, Lars Englberger, Joerg C. Schefold

Original

Health-related quality of life in survivors of septic shock: 6-month follow-up from the ADRENAL trial

Naomi E. Hammond, Simon R. Finfer, Qiang Li, Colman Taylor, Jeremy Cohen, Yaseen Arabi, Rinaldo Bellomo, Laurent Billot, Meg Harward, Christopher Joyce, Colin McArthur, John Myburgh, Anders Perner, Dorrilyn Rajbhandari, Andrew Rhodes, Kelly Thompson, Steve Webb, Balasubramanian Venkatesh, Keri-Anne Cowdrey, Eileen Gilder, Stephanie Long, Lianne McCarthy, Shay McGuinness, Rachael Parke, Kristen Benefield, Yan Chen, Colin McArthur, Rachael McConnochie, Lynette Newby, Rinaldo Bellomo, Glenn Eastwood, Daryl Jones, Leah Peck, Helen Young, Catherine Boschert, John Edington, Jason Fletcher, Julie Smith, Dhaval Ghelani, Kiran Nand, Graham Reece, Treena Sara, Jeremy Bewley, Libby Cole, Lisa Grimmer, Lucy Howie, Shanaz James, Marta Kozlowski, Victoria Phillips, Sanjoy Shah, Katie Sweet, Denise Webster, Irene Bailey, Katrina Ellem, Toni McKenna, Seton Henderson, David Knight, Jan Mehrtens, Emmeline Minto, Sascha Noble, Zia Ansari, Samantha Bates, Craig French, Dashiell Gantner, Sathyajith Velandy Koottayi, Forbes McGain, John Mulder, Anna Tippett, Miriam Towns, Christine Boyd, Verity Calder, Kayla Harris, Carmen Scott, Stephen Wright, Bart De Keulenaer, Edward Litton, Annamaria Palermo, Adrian Regli, Alison Bone, Claire Cattigan, Tania Elderkin, Melissa Fraser, Martina Ni Chonghaile, Neil Orford, Tania Salerno, Maimoonbe Gough, Jody Paxton, Mandy Tallott, James Winearls, Michael Bastick, Robert Cameron, Katrina Ellis, Atul Gaur, Rebecca Gregory, Jessica Naumoff, Mary White, Neeraj Bhadange, Nandan Bhende, Umakant Bhutada, Anand Krishnan, Rebecca Nunn, Judith Ochola, Kristine Ryan, Tracey Sandford, Shannon Treay, Miranda Hardie, Peter Harrigan, Rachael Paton, Emma Pollock, Rachael Whyte, Fatimah Al Ehnidi, Farhan Al Enizi, Eman Al Qasim, Moudi Al Qahtani, Alawi Al Saeedi, Sami Al Solamy, Shmylan Alharbi, Yaseen Arabi, Maamoun Dbsawy, Samir Hadad, Mohammed Muhaidib, Shihab Mundekkadan, Muath Najjar, Vusala Rzayeva, Musharaf Sadat, Sadaf Saedar, Husain Abdulmutalib, Mohammed A. AlMaani, Alaa Ashraf B. AlQurashi, Hani Lababidi, and Pendo Ntinika, Ahmed Abdulmomen, Mariam Al-Ansari, Mohammad Hussein, Alexander Chan, Clair Harris, Phillip Hopkins, Lucy Johnson, Clare Mellis, Leah Thompson, Julia Wendon, Richard Breeze, Michaela Heller, Mick Jennings, Waqas Khaliq, Ingrid Krupe, Ashraf Molokhia, Mathin Mostert, Rosie Reece-Anthony, Bernd Oliver Rose, Anders Aneman, Kerrie-Ann Bradshaw, Lien Lombardo, Claudia Lopez, Sharon Micallef, William O’Regan, Antony Stewart, Lynette Morrison, Kellie Sosnowski, Joanne Sutton, Hayden White, Natalie Soar, Peter Thomas, Josette Wood, Jacqueline Atkins, Stuart Baker, Melissa Finney, Kye Gregory, Amod Karnik, Megan Martin, John Morgan, Maria Pietsch, Jeffrey Presneill, David Sturgess, Melissa Finney, Kye Gregory, Amod Karnik, Megan Martin, David Sturgess, Jefferson Aguila, Bernadette Clatworthy, Anisha Dias, Chantal Hogan, Alex Kazemi, Emmanuel Pelayo, Laura Rust, Rima Song, Anna Tilsley, Tony Williams, Hesham Abdelrahman, Lauren Bulfin, Tim Crozier, Darcy Davey, Jonathan Devine, Dhiraj Dwwivedi, Suzanne Eliott, David Ernest, Michelle Fernando, Kelli Fenech, Pauline Galt, Maja Green, Tammy Lamac, Klaudija Lavrans, Oakleigh Mullan, Paul Ritchie, Stephen Thornhill, Craig Walker, Huichun Wang, Stuart Wilson, Naomi Yarwood, Jane Brailsford, Anne Buckley, Loretta Forbes, Peter Garrett, John Moore, Lauren Murray, Rebecca Gresham, Julie Lowrey, Kristy Masters, Ian Seppelt, Fiona Symonds, Leonie Weisbrodt, Christina Whitehead, Jeanette Bell, Sheila Caniba, Maud Carpenter, Danielle Hacking, Janet Liang, and Caroline Thomas, Olga Burgess, Angaj Ghosh, John Green, Vanessa Leonard-Roberts, Mary Park, Simone Said, Amanda Corley, Lizanne Dalgleish, Melannie Edwards, John Fraser, Paul Jarrett, India Lye, David Sellers, Amy Spooner, Marc Ziegenfuss, Maria Albania, Sumesh Arora, Michelle Campbell, Yahya Shehabi, Yi Shi, Nicola Straiton, Chris Joyce, Jason Meyer, Kelly Perkins, Emma Saylor, Bala Venkatesh, Ellen Venz, James Walsham, Krista Wetzig, David Pogson, Lindsey Roberts, Steve Rose, Amy Bamford, Colin Bergin, Ronald Carrera, Lauren Cooper, Liesl Despy, Karen Ellis, Samantha Harkett, Peter Ip, Philip Pemberton, Martin Pope, Emma Reeves, Catherine Snelson, Elaine Spruce, Arlo Whitehouse, Tony Whitehouse, Maree Duroux, Hamish Pollock, Megan Ratcliffe, Tim Warhurst, Björn Anders Brand, David Lavarett Buck, Vibeke Christiansen, Jette Fredlund Degn, Sofie Riis Jessiman, Maj-Brit Nørregaard Kjær, Vibeke Knudsen, Martin Bruun Madsen, Charlotte Benedikte Mørch Merie, Morten Hylander Møller, Rasmus Müller, Jonas Nielsen, Lizette Helbo Nislev, Anders Perner, Lars Quist, Kis Rønn Uhre, Sofie Louise Rygård, Anne Sofie Svanekier, Hans-Christian Thorsen-Meyer, Jonathan White, Marianne Chapman, Sarah Doherty, Kathleen Glasby, Sonya Kloeden, Stephanie O’Connor, Alex Poole, Justine Rivett, Krishnaswamy Sundararajan, Jenie Butler, Jeremy Cohen, Rachael Dunlop, Paul Jarrett, Melissa Lassig-Smith, Amelia Livermore, Therese Starr, Janine Stuart, Sidharth Agarwal, Margaret Phillips, Dianne Stephens, Jane Thomas, Nicholas Mason, Una Gunter, David Cooper, Rick McAllister, James Anstey, Deborah Barge, Jai Darvall, Rohit D’Costa, Kieron Gorman, Nerina Harley, Andrea Jordan, Christian Karcher, Christopher MacIsaac, Thomas Rechnitzer, Shyamala Sriram, Frances Bass, Simon Bird, Celia Bradford, Anthony Delaney, Simon Finfer, Naomi Hammond, Roger Harris, Anne O’Connor, Maz Razivian, Sarah Wesley, Elizabeth Yarad, Chris Allen, Michelle Barr, Jenny Chamberlain, Janet Ferrier, Elizabeth Jenkinson, Swapna Mathew, Soumya Ray, Anne Marie Sommers, Louise Wallace, Sharon Waterson, Steve Webb, Heidi Buhr, Jennifer Coakley, Jennifer Coles, Mark Daley, David Gattas, Robert Hislop, Debra Hutch, Megan Keir, Heike Koelzow, Mark Lucey, Margherita Murgo, Michael O’Leary, Paul Phipps, Nudrat Rashid, Máté Rudas, Sanjay Tarvade, Richard Totaro, Clive Woolfe, James Wun, Ben Creagh-Brown, Nancileigh Doyle, Lui Forni, Christina Hughes, Daniel Hull, Justin Kirk-Bayley, Laura Montague, Eleanor Radford, Deborah Inskip, Jennene Miller, John Myburgh, Manoj Saxena, Hollmann Aya, Maurizio Cecconi, Nora Di Tomasso, Helen Farrah, Fabrizio Iannuccelli, Joao Macedo, Johannes Mellinghoff, Narenduth Poonuth, Sarah Pruden, Andrew Rhodes, Veronica Robinson-Barnes, Catherine Gray, Philomena Mweu, Emily Whisker, Ian White, Ursula Blanco Alonso, Aneta Bociek, Kathryn Chan, Kate Flynn, Anna Hall, Jessica Hall, Naomi Hare, Andrea Kelly, Katie Lei, Marlies Ostermann, Nicola Purchase, John Smith, Samantha Smith, Barry Dixon, Espedito Faraone, Jennifer Holmes, John Santamaria, Roger Smith, Antony Tobin, Serena Knowles, Serene Leow, Karlee McCann, Priya Nair, Claire Reynolds, Grant Cave, Tim Constable, Phil Hungerford, Amit Kansal, Peter May, Viji Rao, Chris Trethewy, Troy Browne, Jennifer Goodson, Shirley Nelson, Catherine Kurenda, Joanne McIntyre, Sandra Peake, Jennie Phillips-Hughes, Tricia Williams, Rand Butcher, Belinda Foley, Cassandra Lillis, Kerrie Martin, Brunhilde Mulhall, Rebekah Napier, Joe Ogg, Karen Vallance, Amanda Davie, Alison Leech, Elyse Matsen, Amy Owens, Roslyn Purcell, Bala Venkatesh, Vasanth Mariappa, Judy Smith, Kimberly Bury, Shane Finnigan, Elizabeth Heyer, Leonie Jones, Nadine Laffin, Clare Newton, Siva Senthuran, Clare Bolger, Rebecca Cusack, Max Jonas, Karen Salmon, Jewel Barlow-Armstrong, John Durning, Mary La Pine, Tom O’Rourke, Lynn Andrews, Richard Dinsdale, Caitlin Firkin, Anna Hunt, Sally Hurford, Adelaide Jason-Smith, Eden Lesona, Diane Mackle, Agnes McKay Vucago, Lean Navarra, Raulle Sol Cruz, Paul Young, Michael Davis, Wenli Geng, Samantha Jakimowicz, Bronwyn Johnson, Clare Merriman, Martin Sterba

COVID-19 Original

Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia

Laurent Zieleskiewicz, Thibaut Markarian, Alexandre Lopez, Chloé Taguet, Neyla Mohammedi, Mohamed Boucekine, Karine Baumstarck, Guillaume Besch, Gautier Mathon, Gary Duclos, Lionel Bouvet, Pierre Michelet, Bernard Allaouchiche, Kathia Chaumoître, Mathieu Di Bisceglie, Marc Leone

Original

Increased mortality in patients with severe SARS-CoV-2 infection admitted within seven days of disease onset

Elie Azoulay, Muriel Fartoukh, Michael Darmon, Guillaume Géri, Guillaume Voiriot, Thibault Dupont, Lara Zafrani, Lola Girodias, Vincent Labbé, Martin Dres, Alexandra Beurton, Antoine Vieillard-Baron, Alexandre Demoule

What's New in Intensive Care

Acute life-threatening toxicity from CAR T-cell therapy

Elie Azoulay, Michael Darmon, Sandrine Valade

Less is more in Intensive Care

Less contact isolation is more in the ICU: pro

Garyphallia Poulakou, Saad Nseir, George L. Daikos

Less is more in Intensive Care

Less contact isolation is more in the ICU: con

Gabriel Birgand, Jeroen Schouten, Etienne Ruppé

Less is more in Intensive Care

Less contact isolation is more in the ICU: not sure

J. C. Lucet, A. D. Harris, B. Guidet

Understanding the Disease

Understanding necrotizing soft tissue infections in the intensive care unit

Tomas Urbina, Martin Bruun Madsen, Nicolas de Prost

Editorial

Fluid trials: searching for a solution to an age-old problem

Tine Sylvest Meyhoff, Peter Buhl Hjortrup, Anthony Delaney

Editorial

Are the instruments for quality of life assessment comparable between cultures? No

Swagata Tripathy, Sheila Nainan Myatra

Editorial

Focus on gastrointestinal system in critically ill patients

Emmanuel Weiss, Yaseen M. Arabi

Imaging in Intensive Care Medicine

Single lung with bilateral pneumothorax

Li-Ta Keng, Lih-Yu Chang

Imaging in Intensive Care Medicine

A strange position of a venous drainage ECMO cannula

Frederic Caruso, Simone Giglioli, Ilias Bennouna, Daniel De Backer

Imaging in Intensive Care Medicine

An anisocoria that does not look right

Anastasia Saade, Jean-Jacques Tudesq, Guillaume Dumas, Eric Mariotte

Imaging in Intensive Care Medicine