Skip to main content
Erschienen in: Die Anaesthesiologie 10/2018

27.09.2018 | Apoplex | CME

Hämodynamische Zielvariablen auf der Intensivstation

verfasst von: Prof. Dr. M. Heringlake, M. Sander, S. Treskatsch, S. Brandt, C. Schmidt

Erschienen in: Die Anaesthesiologie | Ausgabe 10/2018

Einloggen, um Zugang zu erhalten

Zusammenfassung

Trotz breiter Verfügbarkeit werden in der Praxis nur wenige intensivmedizinisch versorgte Patienten mithilfe des erweiterten hämodynamischen Monitorings überwacht. Pathophysiologische Überlegungen legen nahe, dass dem systemischen Perfusionsdruck (und damit neben dem arteriellen auch dem zentralvenösen Druck), dem kardialen Schlagvolumen und der systemischen Sauerstoffbalance grundlegende Bedeutung in der Aufrechterhaltung einer angemessenen Organperfusion zukommen. Im Einklang mit diesen Überlegungen weisen verschiedene Untersuchungen darauf hin, dass eine zielgerichtete Optimierung dieser hämodynamischen Variablen geeignet ist, Morbidität und Letalität zu reduzieren. Zur Auswahl eines geeigneten Monitorings sollte die biventrikuläre Funktion echokardiographisch evaluiert und – bei Patienten mit eingeschränkter rechtsventrikulärer Funktion und erhöhtem Risiko – idealerweise mithilfe des Pulmonalarterienkatheters überwacht werden. Bei Patienten mit erhaltener rechtsventrikulärer Funktion scheint die transpulmonale Thermodilution unter besonderer Berücksichtigung des extravaskulären Lungenwassers für die Steuerung der Kreislauftherapie auszureichen.
Literatur
1.
Zurück zum Zitat Funcke S, Sander M, Goepfert MS et al (2016) Practice of hemodynamic monitoring and management in German, Austrian, and Swiss intensive care units: the multicenter cross-sectional ICU-CardioMan Study. Ann Intensive Care 6:49PubMedPubMedCentralCrossRef Funcke S, Sander M, Goepfert MS et al (2016) Practice of hemodynamic monitoring and management in German, Austrian, and Swiss intensive care units: the multicenter cross-sectional ICU-CardioMan Study. Ann Intensive Care 6:49PubMedPubMedCentralCrossRef
2.
Zurück zum Zitat Ponikowski P, Voors AA, Anker SD et al (2016) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology. Eur Heart J 37:2129–2200CrossRefPubMed Ponikowski P, Voors AA, Anker SD et al (2016) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology. Eur Heart J 37:2129–2200CrossRefPubMed
4.
Zurück zum Zitat Vincent JL, Quintairos E, Silva A, Couto L Jr, Taccone FS (2016) The value of blood lactate kinetics in critically ill patients: a systematic review. Crit Care 20:257PubMedPubMedCentralCrossRef Vincent JL, Quintairos E, Silva A, Couto L Jr, Taccone FS (2016) The value of blood lactate kinetics in critically ill patients: a systematic review. Crit Care 20:257PubMedPubMedCentralCrossRef
5.
Zurück zum Zitat Mallat J, Lemyze M, Tronchon L, Vallet B, Thevenin D (2016) Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock. World J Crit Care Med 5:47–56PubMedPubMedCentralCrossRef Mallat J, Lemyze M, Tronchon L, Vallet B, Thevenin D (2016) Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock. World J Crit Care Med 5:47–56PubMedPubMedCentralCrossRef
6.
Zurück zum Zitat Heringlake M (2001) Die kardio-renale Achse: Physiologie, Pathophysiologie und klinische Relevanz? Anaesth Intensiv Notf Schmerz 37:250–257CrossRef Heringlake M (2001) Die kardio-renale Achse: Physiologie, Pathophysiologie und klinische Relevanz? Anaesth Intensiv Notf Schmerz 37:250–257CrossRef
7.
Zurück zum Zitat Damman K, van Deursen VM, Navis G, Voors AA, van Veldhuisen DJ, Hillege HL (2009) Increased central venous pressure is associated with impaired renal function and mortality in a broad spectrum of patients with cardiovascular disease. J Am Coll Cardiol 53:582–588PubMedCrossRef Damman K, van Deursen VM, Navis G, Voors AA, van Veldhuisen DJ, Hillege HL (2009) Increased central venous pressure is associated with impaired renal function and mortality in a broad spectrum of patients with cardiovascular disease. J Am Coll Cardiol 53:582–588PubMedCrossRef
8.
Zurück zum Zitat Gu WJ, Hou BL, Kwong JSW et al (2018) Association between intraoperative hypotension and 30-day mortality, major adverse cardiac events, and acute kidney injury after non-cardiac surgery: A meta-analysis of cohort studies. Int J Cardiol 258:68–73PubMedCrossRef Gu WJ, Hou BL, Kwong JSW et al (2018) Association between intraoperative hypotension and 30-day mortality, major adverse cardiac events, and acute kidney injury after non-cardiac surgery: A meta-analysis of cohort studies. Int J Cardiol 258:68–73PubMedCrossRef
9.
Zurück zum Zitat Futier E, Lefrant JY, Guinot PG et al (2017) Effect of individualized vs standard blood pressure management strategies on postoperative organ dysfunction among high-risk patients undergoing major surgery: a randomized clinical trial. JAMA 318(7):1346–1357PubMedPubMedCentralCrossRef Futier E, Lefrant JY, Guinot PG et al (2017) Effect of individualized vs standard blood pressure management strategies on postoperative organ dysfunction among high-risk patients undergoing major surgery: a randomized clinical trial. JAMA 318(7):1346–1357PubMedPubMedCentralCrossRef
10.
Zurück zum Zitat Asfar P, Meziani F, Hamel JF et al (2014) High versus low blood-pressure target in patients with septic shock. N Engl J Med 370:1583–1593PubMedCrossRef Asfar P, Meziani F, Hamel JF et al (2014) High versus low blood-pressure target in patients with septic shock. N Engl J Med 370:1583–1593PubMedCrossRef
11.
Zurück zum Zitat Marik PE, Cavalazzi R (2013) Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense. Crit Care Med 41:1774–1781PubMedCrossRef Marik PE, Cavalazzi R (2013) Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense. Crit Care Med 41:1774–1781PubMedCrossRef
12.
Zurück zum Zitat Williams JB, Peterson ED, Wojdyla D et al (2014) Central venous pressure after coronary artery bypass surgery: does it predict postoperative mortality or renal failure? J Crit Care 29:1006–1010PubMedPubMedCentralCrossRef Williams JB, Peterson ED, Wojdyla D et al (2014) Central venous pressure after coronary artery bypass surgery: does it predict postoperative mortality or renal failure? J Crit Care 29:1006–1010PubMedPubMedCentralCrossRef
13.
Zurück zum Zitat Zhuo DX, Bilchick KC, Mazimba S (2018) Preoperative invasive hemodynamic determinants of survival among patients undergoing aortic or mitral valve surgery. J Cardiothorac Vasc Anesth 32:1273–1280PubMedCrossRef Zhuo DX, Bilchick KC, Mazimba S (2018) Preoperative invasive hemodynamic determinants of survival among patients undergoing aortic or mitral valve surgery. J Cardiothorac Vasc Anesth 32:1273–1280PubMedCrossRef
14.
Zurück zum Zitat Habicher M, Zajonz T, Heringlake M et al (2018) S3 guidelines on intensive medical care of cardiac surgery patients: hemodynamic monitoring and cardiovascular system-an update. Anaesthesist 67:375–379PubMedCrossRef Habicher M, Zajonz T, Heringlake M et al (2018) S3 guidelines on intensive medical care of cardiac surgery patients: hemodynamic monitoring and cardiovascular system-an update. Anaesthesist 67:375–379PubMedCrossRef
15.
Zurück zum Zitat Shoemaker WC, Appel PL, Kram HB (1993) Hemodynamic and oxygen transport responses in survivors and nonsurvivors of high-risk surgery. Crit Care Med 21:977–990PubMedCrossRef Shoemaker WC, Appel PL, Kram HB (1993) Hemodynamic and oxygen transport responses in survivors and nonsurvivors of high-risk surgery. Crit Care Med 21:977–990PubMedCrossRef
16.
Zurück zum Zitat Hamilton MA, Cecconi M, Rhodes A (2011) A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients. Anesth Analg 112:1392–1402CrossRefPubMed Hamilton MA, Cecconi M, Rhodes A (2011) A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients. Anesth Analg 112:1392–1402CrossRefPubMed
17.
Zurück zum Zitat Rivers E, Nguyen B, Havstad S et al (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368–1377PubMedCrossRef Rivers E, Nguyen B, Havstad S et al (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368–1377PubMedCrossRef
18.
Zurück zum Zitat Nguyen HB, Jaehne AK, Jayaprakash N et al (2016) Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE. Crit Care 20:160PubMedPubMedCentralCrossRef Nguyen HB, Jaehne AK, Jayaprakash N et al (2016) Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE. Crit Care 20:160PubMedPubMedCentralCrossRef
19.
Zurück zum Zitat Sander M, Spies CD, Foer A et al (2007) Agreement of central venous saturation and mixed venous saturation in cardiac surgery patients. Intensive Care Med 33:1719–1725PubMedCrossRef Sander M, Spies CD, Foer A et al (2007) Agreement of central venous saturation and mixed venous saturation in cardiac surgery patients. Intensive Care Med 33:1719–1725PubMedCrossRef
21.
Zurück zum Zitat Rady MY, Ryan T, Starr NJ (1998) Perioperative determinants of morbidity and mortality in elderly patients undergoing cardiac surgery. Crit Care Med 26:225–235PubMedCrossRef Rady MY, Ryan T, Starr NJ (1998) Perioperative determinants of morbidity and mortality in elderly patients undergoing cardiac surgery. Crit Care Med 26:225–235PubMedCrossRef
22.
Zurück zum Zitat Renner J, Broch O, Bein B (2012) Fluid management: estimation of fluid status. Anasthesiol Intensivmed Notfallmed Schmerzther 47:470–479PubMedCrossRef Renner J, Broch O, Bein B (2012) Fluid management: estimation of fluid status. Anasthesiol Intensivmed Notfallmed Schmerzther 47:470–479PubMedCrossRef
23.
Zurück zum Zitat Bednarczyk JM, Fridfinnson JA, Kumar A et al (2017) Incorporating dynamic assessment of fluid responsiveness into goal-directed therapy: a systematic review and Meta-analysis. Crit Care Med 45:1538–1545PubMedPubMedCentralCrossRef Bednarczyk JM, Fridfinnson JA, Kumar A et al (2017) Incorporating dynamic assessment of fluid responsiveness into goal-directed therapy: a systematic review and Meta-analysis. Crit Care Med 45:1538–1545PubMedPubMedCentralCrossRef
25.
Zurück zum Zitat Goepfert MS, Richter HP, Zu Eulenburg C et al (2013) Individually optimized hemodynamic therapy reduces complications and length of stay in the intensive care unit: a prospective, randomized controlled trial. Anesthesiology 119:824–836CrossRefPubMed Goepfert MS, Richter HP, Zu Eulenburg C et al (2013) Individually optimized hemodynamic therapy reduces complications and length of stay in the intensive care unit: a prospective, randomized controlled trial. Anesthesiology 119:824–836CrossRefPubMed
27.
Zurück zum Zitat Rudski LG, Lai WW, Afilalo J et al (2010) Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography. J Am Soc Echocardiogr 23:685–713PubMedCrossRef Rudski LG, Lai WW, Afilalo J et al (2010) Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography. J Am Soc Echocardiogr 23:685–713PubMedCrossRef
28.
Zurück zum Zitat Binanay C, Califf RM, Hasselblad V et al (2005) Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial. JAMA 294:1625–1633PubMedCrossRef Binanay C, Califf RM, Hasselblad V et al (2005) Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial. JAMA 294:1625–1633PubMedCrossRef
29.
Zurück zum Zitat Cecconi M, De Backer D, Antonelli M et al (2014) Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med 40:1795–1815PubMedPubMedCentralCrossRef Cecconi M, De Backer D, Antonelli M et al (2014) Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med 40:1795–1815PubMedPubMedCentralCrossRef
30.
Zurück zum Zitat Rhodes A, Evans LE, Alhazzani W et al (2017) Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med 43:304–377CrossRefPubMed Rhodes A, Evans LE, Alhazzani W et al (2017) Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med 43:304–377CrossRefPubMed
Metadaten
Titel
Hämodynamische Zielvariablen auf der Intensivstation
verfasst von
Prof. Dr. M. Heringlake
M. Sander
S. Treskatsch
S. Brandt
C. Schmidt
Publikationsdatum
27.09.2018
Verlag
Springer Medizin
Schlagwort
Apoplex
Erschienen in
Die Anaesthesiologie / Ausgabe 10/2018
Print ISSN: 2731-6858
Elektronische ISSN: 2731-6866
DOI
https://doi.org/10.1007/s00101-018-0489-3

Weitere Artikel der Ausgabe 10/2018

Die Anaesthesiologie 10/2018 Zur Ausgabe