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Erschienen in: Infection 1/2019

07.09.2018 | Brief Report

Interest of immunodeficiency screening in adult after admission in medical intensive care unit for severe infection, a retrospective and a prospective study: the Intensive Care Unit and Primary and Secondary Immunodeficiency (ICUSPID) study

verfasst von: Aurélie Baldolli, Nicolas Martin Silva, Amélie Seguin, Gwenola Maigne, Audrey Sultan, Samuel Deshayes, Damien Du Cheyron, Aurélie Joret, Nizar Mahlaoui, Boris Bienvenu

Erschienen in: Infection | Ausgabe 1/2019

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Abstract

Background

Primary immunodeficiency (PID) in adults is rare and mostly revealed by infections.

Material and Methods

Adults without predisposing factors who were admitted to an intensive care unit (ICU) for infection were screened for PID.

Results

Six PID cases were diagnosed, mostly revealed by encapsulated bacterial infections.

Conclusion

Investigation of PID after ICU discharge should be considered to improve early detection.
Literatur
1.
Zurück zum Zitat Mahlaoui N, Jais JP, Brosselin P, et al. Prevalence of primary immunodeficiencies in France is underestimated. J Allergy Clin Immunol. 2017;140:1731–3.CrossRefPubMed Mahlaoui N, Jais JP, Brosselin P, et al. Prevalence of primary immunodeficiencies in France is underestimated. J Allergy Clin Immunol. 2017;140:1731–3.CrossRefPubMed
2.
Zurück zum Zitat Picard C, Bobby Gaspar H, Al-Herz W, et al. International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee report on inborn errors of immunity. J Clin Immunol. 2017;38:96–128.CrossRefPubMedPubMedCentral Picard C, Bobby Gaspar H, Al-Herz W, et al. International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee report on inborn errors of immunity. J Clin Immunol. 2017;38:96–128.CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Srinivasa BT, Alizadehfar R, Desrosiers M, Shuster J, Pai NP, Tsoukas CM. Adult primary immune deficiency: what are we missing? Am J Med. 2012;125:779–86.CrossRefPubMed Srinivasa BT, Alizadehfar R, Desrosiers M, Shuster J, Pai NP, Tsoukas CM. Adult primary immune deficiency: what are we missing? Am J Med. 2012;125:779–86.CrossRefPubMed
5.
Zurück zum Zitat Zhou J, Qian C, Zhao M, et al. Epidemiology and outcome of severe sepsis and septic shock in intensive care units in mainland China. PLoS One. 2014;9:e107181.CrossRefPubMedPubMedCentral Zhou J, Qian C, Zhao M, et al. Epidemiology and outcome of severe sepsis and septic shock in intensive care units in mainland China. PLoS One. 2014;9:e107181.CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Conley ME, Notarangelo LD, Etzioni A. Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies). Clin Immunol. 1999;93:190–7.CrossRefPubMed Conley ME, Notarangelo LD, Etzioni A. Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies). Clin Immunol. 1999;93:190–7.CrossRefPubMed
7.
Zurück zum Zitat Lopez B, Bahuaud M, Fieschi C, et al. Value of the overall pneumococcal polysaccharide response in the diagnosis of primary humoral immunodeficiencies. Front Immunol. 2017;8:1862.CrossRefPubMedPubMedCentral Lopez B, Bahuaud M, Fieschi C, et al. Value of the overall pneumococcal polysaccharide response in the diagnosis of primary humoral immunodeficiencies. Front Immunol. 2017;8:1862.CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Suavinho E, de Napolis AC, Segundo GR. Primary immunodeficiency investigation in patients during and after hospitalization in a pediatric intensive care unit. Rev Paul Pediatr. 2014;32:32–6.CrossRefPubMedPubMedCentral Suavinho E, de Napolis AC, Segundo GR. Primary immunodeficiency investigation in patients during and after hospitalization in a pediatric intensive care unit. Rev Paul Pediatr. 2014;32:32–6.CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Gathmann B, Mahlaoui N, Ceredih, et al. Clinical picture and treatment of 2212 patients with common variable immunodeficiency. J Allergy Clin Immunol. 2014;134:116–26.CrossRefPubMed Gathmann B, Mahlaoui N, Ceredih, et al. Clinical picture and treatment of 2212 patients with common variable immunodeficiency. J Allergy Clin Immunol. 2014;134:116–26.CrossRefPubMed
10.
Zurück zum Zitat Lopez B, Boucher A, Bahuaud M, et al. Specific polysaccharide antibody deficiency revealed by severe bacterial infections in adulthood: a report on 11 cases. Clin Infect Dis. 2017;65:328–31.CrossRefPubMed Lopez B, Boucher A, Bahuaud M, et al. Specific polysaccharide antibody deficiency revealed by severe bacterial infections in adulthood: a report on 11 cases. Clin Infect Dis. 2017;65:328–31.CrossRefPubMed
11.
Zurück zum Zitat Sanges S, Wallet F, Blondiaux N, et al. Diagnosis of primary antibody and complement deficiencies in young adults after a first invasive bacterial infection. Clin Microbiol Infect. 2017;23:576CrossRefPubMed Sanges S, Wallet F, Blondiaux N, et al. Diagnosis of primary antibody and complement deficiencies in young adults after a first invasive bacterial infection. Clin Microbiol Infect. 2017;23:576CrossRefPubMed
12.
Zurück zum Zitat Audemard-Verger A, Descloux E, Ponard D, et al. Infections revealing complement deficiency in adults: a French nationwide study enrolling 41 patients. Medicine (Baltimore). 2016;95:e3548.CrossRef Audemard-Verger A, Descloux E, Ponard D, et al. Infections revealing complement deficiency in adults: a French nationwide study enrolling 41 patients. Medicine (Baltimore). 2016;95:e3548.CrossRef
Metadaten
Titel
Interest of immunodeficiency screening in adult after admission in medical intensive care unit for severe infection, a retrospective and a prospective study: the Intensive Care Unit and Primary and Secondary Immunodeficiency (ICUSPID) study
verfasst von
Aurélie Baldolli
Nicolas Martin Silva
Amélie Seguin
Gwenola Maigne
Audrey Sultan
Samuel Deshayes
Damien Du Cheyron
Aurélie Joret
Nizar Mahlaoui
Boris Bienvenu
Publikationsdatum
07.09.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Infection / Ausgabe 1/2019
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-018-1215-4

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