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Erschienen in: Journal of Artificial Organs 1/2019

18.08.2018 | Original Article

Interhospital transport of ARDS patients on extracorporeal membrane oxygenation

verfasst von: Jan Florian Heuer, Moritz Mirschel, Annalen Bleckmann, Michael Quintel, Onnen Moerer

Erschienen in: Journal of Artificial Organs | Ausgabe 1/2019

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Abstract

Veno-venous extracorporeal membrane oxygenation (ECMO) can be a lifesaving therapy for patients with severe acute respiratory distress syndrome (ARDS). ECMO is a technically complex and challenging procedure and should therefore only be performed in specialized centers. Transporting ARDS patients to ECMO centers for treatment can be dangerous because of the risk of hypoxemia during transport. This raises the question if ECMO should not be already initiated in the transferring hospital before transport. Over a 5-year period, we studied ARDS patients who had been transported to our department by our mobile ECMO team for further treatment after ECMO had already been initiated at the referring hospital. Data for analysis were obtained from our patient data management system (PDMS), the referral documents, and from the referring hospitals. Seventy-five patients meeting the selection criteria were studied. All had been successfully cannulated in the transferring hospitals. They were transported to our ECMO center by helicopter (n = 34) or mobile intensive care units (n = 41). No patient died during transport. Forty four of the patients were transported at night. Twenty-six patients (35%) died in our intensive care unit due to a therapy refractory course, comorbidities or limitation of therapy. Patients on ECMO therapy can be safely transferred to a specialist center. Setting up ECMO in an unfamiliar location and the subsequent patient transport can be very challenging and should only be performed by a highly trained, experienced team.
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Literatur
1.
Zurück zum Zitat Ventilation with lower. tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. the acute respiratory distress syndrome network. N Engl J Med. 2000;342:1301–8.CrossRef Ventilation with lower. tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. the acute respiratory distress syndrome network. N Engl J Med. 2000;342:1301–8.CrossRef
2.
Zurück zum Zitat Guerin C, Reignier J, Richard JC. Prone positioning in the acute respiratory distress syndrome. N Engl J Med. 2013;369:980–1.PubMed Guerin C, Reignier J, Richard JC. Prone positioning in the acute respiratory distress syndrome. N Engl J Med. 2013;369:980–1.PubMed
3.
Zurück zum Zitat Amato MB, Meade MO, Slutsky AS, Brochard L, Costa EL, Schoenfeld DA, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015;372:747–55.CrossRefPubMed Amato MB, Meade MO, Slutsky AS, Brochard L, Costa EL, Schoenfeld DA, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015;372:747–55.CrossRefPubMed
4.
Zurück zum Zitat Papazian L, Forel JM, Gacouin A, Penot-Ragon C, Perrin G, Loundou A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363:1107–16.CrossRefPubMed Papazian L, Forel JM, Gacouin A, Penot-Ragon C, Perrin G, Loundou A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363:1107–16.CrossRefPubMed
5.
Zurück zum Zitat Forrest P, Ratchford J, Burns B, Herkes R, Jackson A, Plunkett B, et al. Retrieval of critically ill adults using extracorporeal membrane oxygenation: an Australian experience. Intensive Care Med. 2011;37:824–30.CrossRefPubMed Forrest P, Ratchford J, Burns B, Herkes R, Jackson A, Plunkett B, et al. Retrieval of critically ill adults using extracorporeal membrane oxygenation: an Australian experience. Intensive Care Med. 2011;37:824–30.CrossRefPubMed
6.
Zurück zum Zitat Lucchini A, De Felippis C, Elli S, Gariboldi R, Vimercati S, Tundo P, et al. Mobile ECMO team for inter-hospital transportation of patients with ARDS: a retrospective case series. Heart Lung Vessels. 2014;6:262–73.PubMed Lucchini A, De Felippis C, Elli S, Gariboldi R, Vimercati S, Tundo P, et al. Mobile ECMO team for inter-hospital transportation of patients with ARDS: a retrospective case series. Heart Lung Vessels. 2014;6:262–73.PubMed
7.
Zurück zum Zitat Peek GJ, Mugford M, Tiruvoipati R, Wilson A, Allen E, Thalanany MM, et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet. 2009;374:1351–63.CrossRefPubMed Peek GJ, Mugford M, Tiruvoipati R, Wilson A, Allen E, Thalanany MM, et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet. 2009;374:1351–63.CrossRefPubMed
8.
Zurück zum Zitat Biscotti M, Agerstrand C, Abrams D, Ginsburg M, Sonett J, Mongero L, et al. One hundred transports on extracorporeal support to an extracorporeal membrane oxygenation center. Ann Thorac Surg. 2015;100:34–9. (discussion 9–40).CrossRefPubMed Biscotti M, Agerstrand C, Abrams D, Ginsburg M, Sonett J, Mongero L, et al. One hundred transports on extracorporeal support to an extracorporeal membrane oxygenation center. Ann Thorac Surg. 2015;100:34–9. (discussion 9–40).CrossRefPubMed
9.
Zurück zum Zitat Roch A, Hraiech S, Masson E, Grisoli D, Forel JM, Boucekine M, et al. Outcome of acute respiratory distress syndrome patients treated with extracorporeal membrane oxygenation and brought to a referral center. Intensive Care Med. 2014;40:74–83.CrossRefPubMed Roch A, Hraiech S, Masson E, Grisoli D, Forel JM, Boucekine M, et al. Outcome of acute respiratory distress syndrome patients treated with extracorporeal membrane oxygenation and brought to a referral center. Intensive Care Med. 2014;40:74–83.CrossRefPubMed
10.
Zurück zum Zitat Broman LM, Holzgraefe B, Palmer K, Frenckner B. The Stockholm experience: interhospital transports on extracorporeal membrane oxygenation. Crit Care. 2015;19:278.CrossRefPubMedPubMedCentral Broman LM, Holzgraefe B, Palmer K, Frenckner B. The Stockholm experience: interhospital transports on extracorporeal membrane oxygenation. Crit Care. 2015;19:278.CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Raspe C, Ruckert F, Metz D, Hofmann B, Neitzel T, Stiller M, et al. Inter-hospital transfer of ECMO-assisted patients with a portable miniaturized ECMO device: 4 years of experience. Perfusion. 2015;30:52–9.CrossRefPubMed Raspe C, Ruckert F, Metz D, Hofmann B, Neitzel T, Stiller M, et al. Inter-hospital transfer of ECMO-assisted patients with a portable miniaturized ECMO device: 4 years of experience. Perfusion. 2015;30:52–9.CrossRefPubMed
13.
Zurück zum Zitat Zambon M, Vincent JL. Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest. 2008;133:1120–7.CrossRefPubMed Zambon M, Vincent JL. Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest. 2008;133:1120–7.CrossRefPubMed
14.
Zurück zum Zitat Costa EL, Slutsky AS, Amato MB. Driving pressure as a key ventilation variable. N Engl J Med. 2015;372:2072.PubMed Costa EL, Slutsky AS, Amato MB. Driving pressure as a key ventilation variable. N Engl J Med. 2015;372:2072.PubMed
15.
Zurück zum Zitat Parmentier-Decrucq E, Poissy J, Favory R, Nseir S, Onimus T, Guerry MJ, et al. Adverse events during intrahospital transport of critically ill patients: incidence and risk factors. Ann Intensive Care. 2013;3:10.CrossRefPubMedPubMedCentral Parmentier-Decrucq E, Poissy J, Favory R, Nseir S, Onimus T, Guerry MJ, et al. Adverse events during intrahospital transport of critically ill patients: incidence and risk factors. Ann Intensive Care. 2013;3:10.CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Ligtenberg JJ, Arnold LG, Stienstra Y, van der Werf TS, Meertens JH, Tulleken JE, et al. Quality of interhospital transport of critically ill patients: a prospective audit. Crit Care. 2005;9:R446-51.CrossRefPubMed Ligtenberg JJ, Arnold LG, Stienstra Y, van der Werf TS, Meertens JH, Tulleken JE, et al. Quality of interhospital transport of critically ill patients: a prospective audit. Crit Care. 2005;9:R446-51.CrossRefPubMed
17.
Zurück zum Zitat Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, deBoisblanc B, et al. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med. 2006;354:2564–75.CrossRefPubMed Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, deBoisblanc B, et al. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med. 2006;354:2564–75.CrossRefPubMed
18.
Zurück zum Zitat Sommer N, Dietrich A, Schermuly RT, Ghofrani HA, Gudermann T, Schulz R, et al. Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms. Eur Respir J. 2008;32:1639–51.CrossRefPubMed Sommer N, Dietrich A, Schermuly RT, Ghofrani HA, Gudermann T, Schulz R, et al. Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms. Eur Respir J. 2008;32:1639–51.CrossRefPubMed
19.
Zurück zum Zitat Curley G, Kavanagh BP, Laffey JG. Hypocapnia and the injured brain: more harm than benefit. Crit Care Med. 2010;38:1348–59.CrossRefPubMed Curley G, Kavanagh BP, Laffey JG. Hypocapnia and the injured brain: more harm than benefit. Crit Care Med. 2010;38:1348–59.CrossRefPubMed
20.
Zurück zum Zitat Pappalardo F, Pieri M, Greco T, Patroniti N, Pesenti A, Arcadipane A, et al. Predicting mortality risk in patients undergoing venovenous ECMO for ARDS due to influenza A (H1N1) pneumonia: the ECMOnet score. Intensive Care Med. 2013;39:275–81.CrossRefPubMed Pappalardo F, Pieri M, Greco T, Patroniti N, Pesenti A, Arcadipane A, et al. Predicting mortality risk in patients undergoing venovenous ECMO for ARDS due to influenza A (H1N1) pneumonia: the ECMOnet score. Intensive Care Med. 2013;39:275–81.CrossRefPubMed
Metadaten
Titel
Interhospital transport of ARDS patients on extracorporeal membrane oxygenation
verfasst von
Jan Florian Heuer
Moritz Mirschel
Annalen Bleckmann
Michael Quintel
Onnen Moerer
Publikationsdatum
18.08.2018
Verlag
Springer Japan
Erschienen in
Journal of Artificial Organs / Ausgabe 1/2019
Print ISSN: 1434-7229
Elektronische ISSN: 1619-0904
DOI
https://doi.org/10.1007/s10047-018-1065-y

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