International Journal of Clinical Oncology

PMDA regulatory update on approval and revision of the precautions for use of anticancer drugs; approval of sacituzumab govitecan for breast cancer, fruquintinib for colorectal cancer, amivantamab for lung cancer, repotrectinib for lung cancer, tasurgratinib for biliary tract cancer, enfortumab vedotin plus pembrolizumab for urothelial cancer, and dabrafenib plus trametinib for glioma in Japan

• PMDA Regulatory Update

Noriomi Matsumura, Masaki Mandai

Conversion surgery for esophageal and esophagogastric junction cancer

• Open Access
• JSCO Board of Directors Series

Yoshiaki Shoji, Kohei Kanamori, Kazuo Koyanagi, Tetsuya Otsuka, Rie Nakashima, Kohei Tajima, Mika Ogimi, Yamato Ninomiya, Miho Yamamoto, Akihito Kazuno, Takayuki Nishi, Masaki Mori

Efficacy and safety of dexamethasone sparing for the prevention of nausea and vomiting associated with moderately emetogenic chemotherapy: a systematic review and meta-analysis of Clinical Practice Guidelines for Antiemesis 2023 from Japan Society of Clinical Oncology

• Special Article

Kazuhisa Nakashima, Ayako Yokomizo, Michiyasu Murakami, Kenji Okita, Makoto Wada, Keiko Iino, Tatsuo Akechi, Hirotoshi Iihara, Chiyo K. Imamura, Ayako Okuyama, Keiko Ozawa, Yong-il Kim, Hidenori Sasaki, Eriko Satomi, Masayuki Takeda, Ryuhei Tanaka, Takako Eguchi Nakajima, Naoki Nakamura, Junichi Nishimura, Mayumi Noda, Kazumi Hayashi, Takahiro Higashi, Narikazu Boku, Koji Matsumoto, Yoko Matsumoto, Nobuyuki Yamamoto, Kenjiro Aogi, Masakazu Abe

A machine learning-based method for feature reduction of methylation data for the classification of cancer tissue origin

• Open Access
• Original Article

Marco A. De Velasco, Kazuko Sakai, Seiichiro Mitani, Yurie Kura, Shuji Minamoto, Takahiro Haeno, Hidetoshi Hayashi, Kazuto Nishio

Local extension findings on MRI compensate for the ability of pathological staging to predict oncological outcome

• Original Article

Takahito Wakamiya, Yasuo Kohjimoto, Shimpei Yamashita, Isao Hara

Relationship between magnesium dosage and the preventive effect on cisplatin-induced nephrotoxicity: meta-analysis and meta-regression analysis

• Original Article

Keisuke Okamoto, Yoshitaka Saito, Atsushi Yamaguchi, Katsuya Narumi, Masaki Kobayashi

First-line pembrolizumab with or without chemotherapy for recurrent or metastatic head and neck squamous cell carcinoma: 5-year follow-up of the Japanese population of KEYNOTE‑048

• Open Access
• Original Article

Nobuhiko Oridate, Shunji Takahashi, Kaoru Tanaka, Yasushi Shimizu, Yasushi Fujimoto, Koji Matsumoto, Tomoya Yokota, Tomoko Yamazaki, Masanobu Takahashi, Tsutomu Ueda, Nobuhiro Hanai, Hironori Yamaguchi, Hiroki Hara, Tomokazu Yoshizaki, Ryuji Yasumatsu, Masahiro Nakayama, Kiyoto Shiga, Takashi Fujii, Kenji Mitsugi, Kenichi Takahashi, Nijiro Nohata, Burak Gumuscu, Nati Lerman, Makoto Tahara

Clinical impact of concomitant BIO-three use in advanced or recurrent non-small cell lung cancer treated with immune-checkpoint inhibitor

• Original Article

Hitomi Nakatsukasa, Masaya Takahashi, Masahito Shibano, Yusuke Ishigami, Tomoya Kawaguchi, Yasutaka Nakamura, Hiroyasu Kaneda

Neutrophil-to-lymphocyte ratio at the end of treatment with CDK4/6 inhibitors is an independent prognostic factor for ER-positive HER2-negative advanced breast cancer

• Original Article

Ayumu Mitsuyoshi, Masayuki Nagahashi, Haruka Kanaoka, Aoi Oshiro, Yusa Togashi, Akira Hattori, Junko Tsuchida, Tomoko Higuchi, Arisa Nishimukai, Keiko Murase, Yuichi Takatsuka, Yasuo Miyoshi

Diagnostic performance of TILs–US score and LPBC in biopsy specimens for predicting pathological complete response in patients with breast cancer

• Open Access
• Original Article

Hideo Shigematsu, Kayo Fukui, Akiko Kanou, Erika Yokoyama, Makiko Tanaka, Mutsumi Fujimoto, Kanako Suzuki, Haruka Ikejiri, Ai Amioka, Emiko Hiraoka, Shinsuke Sasada, Akiko Emi, Tetsuya Nakagiri, Koji Arihiro, Morihito Okada

Fourteen-year follow-up results of imatinib therapy in patients with unresectable and metastatic gastrointestinal stromal tumors

• Original Article

Tatsuo Kanda, Hiroshi Ichikawa, Takashi Ishikawa, Yusuke Muneoka, Yosuke Kano, Tetsuya Naito, Satoshi Suzuki, Toshifumi Wakai

Real-world outcomes of FOLFOXIRI plus bevacizumab in patients with metastatic colorectal cancer: the JSCCR-TRIPON study

• Original Article

Yoshiyuki Yamamoto, Hiroki Yukami, Tatsuro Yamaguchi, Hisatsugu Ohori, Sachiko Nagasu, Yoshinori Kagawa, Naotoshi Sugimoto, Hiromichi Sonoda, Kentaro Yamazaki, Atsuo Takashima, Hiroyuki Okuyama, Hiroko Hasegawa, Chihiro Kondo, Eishi Baba, Toshihiko Matsumoto, Yasuyuki Kawamoto, Masato Kataoka, Yoshiaki Shindo, Toshiaki Ishikawa, Taito Esaki, Yosuke Kito, Takeo Sato, Taro Funakoshi, Toshifumi Yamaguchi, Yasuhiro Shimada, Toshikazu Moriwaki

Molecular profiling of risk factors for relapse in Japanese patients with stage II colorectal cancer: a retrospective cohort study

• Original Article

Shunsuke Kasai, Hiroyasu Kagawa, Keiichi Hatakeyama, Akio Shiomi, Shoichi Manabe, Yusuke Yamaoka, Yusuke Tanaka, Takahiro Igaki, Takeshi Nagashima, Keiichi Ohshima, Kenichi Urakami, Yasuto Akiyama, Yusuke Kinugasa, Ken Yamaguchi

Lateral node metastasis in low rectal cancer as a hallmark to predict recurrence patterns

• Original Article

Eiji Shinto, Hideyuki Ike, Masaaki Ito, Keiichi Takahashi, Masayuki Ohue, Yukihide Kanemitsu, Takeshi Suto, Tetsushi Kinugasa, Jun Watanabe, Jin-ichi Hida, Michio Itabashi, Heita Ozawa, Hiroaki Nozawa, Yojiro Hashiguchi, Kazuo Hase, Kenichi Sugihara, Yoichi Ajioka

Clinical utility of a comprehensive genomic profiling test for patient with advanced biliary tract cancer

• Original Article

Hiroki Inada, Hideaki Miyamoto, Satoru Shinriki, Hisanobu Oda, Satoshi Narahara, Motohiro Yoshinari, Katsuya Nagaoka, Daiki Yoshii, Kotaro Fukubayashi, Hiromitsu Hayashi, Hideo Baba, Kisato Nosaka, Yasuhito Tanaka

Clinical outcomes of first-line combination therapy with immune checkpoint inhibitor for metastatic non-clear cell renal cell carcinoma: a multi-institutional retrospective study in Japan

• Open Access
• Original Article

Akihiro Yoshimura, Taigo Kato, Yasutomo Nakai, Masao Tsujihata, Shingo Toyoda, Mototaka Sato, Kyosuke Matsuzaki, Wataru Nakata, Tetsuya Takao, Syunsuke Inoguchi, Yohei Okuda, Gaku Yamamichi, Yu Ishizuya, Yoshiyuki Yamamoto, Koji Hatano, Atsunari Kawashima, Shingo Takada, Hitoshi Inoue, Kensaku Nishimura, Osamu Miyake, Kazutoshi Fujita, Masashi Nakayama, Kazuo Nishimura, Norio Nonomura

Efficacy and safety of adjuvant nivolumab after radical surgery for high-risk urothelial carcinoma: a preliminary report of real-world data from a single institution

• Original Article

Yosuke Yasuda, Noboru Numao, Tetsuya Urasaki, Ryosuke Oki, Tomohiko Oguchi, Ryo Fujiwara, Yusuke Yoneoka, Kosuke Takemura, Junji Yonese, Takeshi Yuasa

Efficacy and safety of lenvatinib and pembrolizumab as first-line treatment for advanced renal cell carcinoma patients: real-world experience in Japan

• Original Article

Takuto Hara, Kotaro Suzuki, Yasuyoshi Okamura, Koji Chiba, Ryo Sato, Yuto Matsushita, Keita Tamura, Gaku Ishikawa, Atsushi Otsuka, Hideaki Miyake

Reproductive organ involvement in women undergoing radical cystectomy for urothelial bladder cancer: a nationwide multicenter study

• Original Article

Minoru Kato, Rikiya Taoka, Jun Miki, Ryoichi Saito, Wataru Fukuokaya, Yoshiyuki Matsui, Shoma Yamamoto, Taisuke Matsue, Shingo Hatakeyama, Takashi Kawahara, Ayumu Matsuda, Taketo Kawai, Tomokazu Sazuka, Takeshi Sano, Fumihiko Urabe, Soki Kashima, Hirohito Naito, Yoji Murakami, Makito Miyake, Kei Daizumoto, Yuto Matsushita, Takuji Hayashi, Junichi Inokuchi, Yusuke Sugino, Kenichiro Shiga, Noriya Yamaguchi, Shingo Yamamoto, Keiji Yasue, Takashige Abe, Shotaro Nakanishi, Katsuyoshi Hashine, Masato Fujii, Kiyoaki Nishihara, Hiroaki Matsumoto, Shuichi Tatarano, Koichiro Wada, Sho Sekito, Ryo Maruyama, Naotaka Nishiyama, Hiroyuki Nishiyama, Hiroshi Kitamura, Junji Uchida

Real-world outcomes in patients with metastatic castration-resistant prostate cancer beyond progression after upfront androgen receptor signaling inhibitor

• Original Article

Yutaka Yamamoto, Saizo Fujimoto, Mamoru Hashimoto, Takafumi Minami, Wataru Fukuokaya, Takafumi Yanagisawa, Masanobu Saruta, Kiyoshi Takahara, Kazuki Nishimura, Takuya Tsujino, Yuta Nakamori, Takeshi Hashimoto, Takahiro Kimura, Ryoichi Shiroki, Haruhito Azuma, Yoshio Ohno, Kazutoshi Fujita

Out-of-pocket fertility preservation expenses: data from a Japanese nationwide multicenter survey

• Open Access
• Original Article

Masanori Ono, Yasushi Takai, Miyuki Harada, Akihito Horie, Yidan Dai, Eiji Kikuchi, Mitsuru Miyachi, Tetsuya Yamamoto, Nobuharu Fujii, Hiroaki Kajiyama, Atsushi Manabe, Toshiaki Yasuoka, Shinji Katsuragi, Keiko Mekaru, Tadashi Maezawa, Yuki Horage, Shinsuke Kataoka, Robert Nakayama, Takako Eguchi Nakajima, Fuminori Kimura, Chikako Shimizu, Kohei Sugimoto, Seido Takae, Yasushi Yumura, Hirotaka Nishi, Tatsuro Furui, Ken-Ichirou Morishige, Chie Watanabe, Yutaka Osuga, Nao Suzuki

Real-world application of comprehensive genomic profiling for gynecological malignancies: a multicenter observational study

• Original Article

Mayu Fukuda, Koji Yamanoi, Nobutaka Hayashi, Yasushi Kotani, Kazuki Yamano, Hisanori Matsumoto, Takahito Ashihara, Kaoru Abiko, Yukio Yamanishi, Yoko Iemura, Mana Taki, Ryusuke Murakami, Akihito Horie, Ken Yamaguchi, Junzo Hamanishi, Masaki Mandai

Pembrolizumab in Japanese patients with primary mediastinal large B-cell lymphoma: results from the KEYNOTE-A33 study

• Original Article

Koji Kato, Sosuke Nakamura, Akira Wakana, Yasuhiro Koh, Koji Izutsu

Genomic landscape of cutaneous, acral, mucosal, and uveal melanoma in Japan: analysis of clinical comprehensive genomic profiling data

• Original Article

Tokimasa Hida, Junji Kato, Masashi Idogawa, Takashi Tokino, Hisashi Uhara

List of reviewers 2023–2024

• Acknowledgments