Intestinal Lipomatosis and Chemotherapy: A Growing Concern

Excerpt

A 41-year-old Hispanic male was referred to outpatient Gastroenterology for a colonoscopy and esophagogastroduodenoscopy (EGD) due to the recent recognition of iron deficiency anemia. He also suffered from obesity, nonalcoholic steatohepatitis, and type 2 diabetes mellitus. His past history included testicular non-seminoma germ cell tumor treated with right orchiectomy and chemotherapy with BEP (bleomycin, etoposide, and cisplatin) 12 years previously, followed by bilateral aorto-iliac embolectomies during BEP chemotherapy. Five years prior to referral, an ileocecal intussusception, due to a 6.2 cm cecal lipoma, led to ileo-colectomy and revealed the presence of intestinal lipomatosis. His current symptoms consist of intermittent postprandial epigastric pain with associated nausea and vomiting for 3 months, and mild chronic constipation. There was no overt gastrointestinal bleeding. One month prior to this admission, he had been hospitalized for presumed prostatitis and treated with a 3-week course of trimethoprim–sulfamethoxazole. His current medications include daily metformin, glipizide, omeprazole, lisinopril, lactulose, and ibuprofen. He occasionally drinks alcohol but avoids tobacco or other recreational drugs. His family history is irrelevant. …