Intrafocal injection of tranexamic acid decreases early return to hospital after high tibial osteotomy
- 28.06.2024
- Orthopaedic Surgery
Erschienen in:
- Verfasst von
- Julia Edward
- Fidaa Al-Shakfa
- Nicholas Newman
- Frédéric Lavoie
- Erschienen in
- Archives of Orthopaedic and Trauma Surgery | Ausgabe 7/2024
Abstract
Introduction
High tibial osteotomy (HTO) is a surgery performed to treat the symptoms and prevent the progression of medial osteoarthritis. Post-operative bleeding has led to early returns to hospital following surgery. Intrafocal injection of tranexamic acid (TXA) could reduce this bleeding complication. The objective of the study was to evaluate the effect of TXA during HTO on the incidence of post-operative complications and early returns to hospital.
Materials and methods
This retrospective study included 251 cases of HTO performed between May 2012 and October 2021, with the use of TXA introduced in May 2017. The experimental (n = 102) and control (n = 149) groups were compared as to the rate of post-operative early returns. The influence of confounding factors was evaluated, including age, sex, body mass index (BMI), tobacco use, grade of medial femorotibial osteoarthritis (MFTO), magnitude of angular correction (MAC), and surgery duration.
Results
No statistically significant difference was found between the groups with regards to all variables except age. The experimental group was significantly older (54.4 years; σ = 7.5) than the control group (50.4 years; σ = 7.9; p < 0.001). We observed a decrease in emergency department (ED) visits in the experimental group (15.7%) compared to the control (30.2%; p = 0.008) and a decrease in early returns in the experimental group (28.4%) compared to the control (40.5%; p = 0.049). No statistically significant difference in demographic data, MFTO, or MAC was found among patients with and without an early return, in both the experimental and control groups.
Conclusion
The intrafocal injection of TXA during HTO decreases early returns to hospital.
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- Titel
- Intrafocal injection of tranexamic acid decreases early return to hospital after high tibial osteotomy
- Verfasst von
-
Julia Edward
Fidaa Al-Shakfa
Nicholas Newman
Frédéric Lavoie
- Publikationsdatum
- 28.06.2024
- Verlag
- Springer Berlin Heidelberg
- Erschienen in
-
Archives of Orthopaedic and Trauma Surgery / Ausgabe 7/2024
Print ISSN: 0936-8051
Elektronische ISSN: 1434-3916 - DOI
- https://doi.org/10.1007/s00402-024-05411-5
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