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01.11.2010 | Clinical Research | Ausgabe 11/2010

Obesity Surgery 11/2010

Intragastric Balloon Followed by Diet vs Intragastric Balloon Followed by Another Balloon: A Prospective Study on 100 Patients

Zeitschrift:
Obesity Surgery > Ausgabe 11/2010
Autoren:
Alfredo Genco, Massimiliano Cipriano, Vincenzo Bacci, Roberta Maselli, Emanuela Paone, Michele Lorenzo, Nicola Basso

Abstract

Aim of this study is to compare the efficacy of BioEnterics Intragastric Balloon (BIB®) followed by diet with BIB followed by another BIB. A prospective study was designed: a homogeneous group of 100 obese patients (age range 25–35, BMI range 40.0–44.9, M/F ratio 1/4) was allocated into two groups according to procedure: BIB (6 months) followed by diet therapy (7 months; group A = 50 pts), BIB positioning followed by another BIB after 1 month (group B = 50 pts). Baseline demographics were similar in both groups (Group A 10M/40F; mean age 31.4 ± 2.6; range 25–35; mean weight 106.3 ± 12.5 Kg; range 88–150; mean BMI 42.6±2.7 Kg/m2; range 40.2–43.8; Group B 10M/40F; mean age 32.1 ± 2.1; range 25–35; mean weight 107.1 ± 11.9 Kg; range 90–150; mean BMI 42.9 ± 2.3; range 40.2–43.9). In both groups, weight loss parameters (Kg, BMI, and % EBL) were considered. Statistics were by Fisher’s exact test (p < 0.05 was considered significant). At the time of 1st BIB removal, weight loss parameters in both groups were not significantly different: Group A: mean weight was 83.7±19.1 (range 52–151); mean BMI 34.2 ± 3.9 (range 32.4–43.8); and mean %EBL 43.5 ± 21.1 (range 0–68). Group B: mean weight was 84.9 ± 18.3 (range 50–148); mean BMI 34.8 ± 3.3 (range 32.4–43.8); and mean % EBL 45.2 ± 22.5% (range 0–68). At the study end, weight loss parameters were significantly lower in patients who underwent consecutive BIB (p < 0.05): mean BMI was 30.9 ± 7.2 Kg/m2 (range 24–40), and 35.9 ± 9.7 Kg/m2 (range 34–42); mean % EBL was 51.9 ± 24.6% (range 0–100) and 25.1 ± 26.2% (range 0–100) in group B and A, respectively. As compared with diet, a second intragastric balloon can be positioned without difficulties, achieving good results with continuous weight loss.

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