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Erschienen in: European Journal of Plastic Surgery 8/2012

01.08.2012 | Ideas and Innovations

Intralesional cryosurgery for the treatment of basal cell carcinoma in an elderly patient

verfasst von: Yaron Har-Shai, Lior Har-Shai, Miriam Lurie, Edmond Sabo

Erschienen in: European Journal of Plastic Surgery | Ausgabe 8/2012

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Abstract

The incidence of basal cell carcinoma (BCC) on the lower extremities of elderly patients, who have co-morbidity, is rising. The surgical technique to treat those skin neoplasms on the legs should take into account difficulties in wound healing, dehiscence, or necrosis of the surgical wound, failed skin grafting, and wound infection due to blood supply and innervation disturbances and reduced quality of the skin. Spray/contact cryosurgery is one of the well-established, older therapies for BCC and is widely used with hardly any contraindications and with a high cure rate. This case report is the first in the medical literature to present a successful removal of two BCCs on the leg of an elderly patient by employing a novel and new intralesional cryosurgery technology.
Literatur
1.
Zurück zum Zitat Roewert-Huber J, Lange-Asschenfeldt B, Stockfleth E, Kerl H (2007) Epidemiology and aetiology of basal cell carcinoma. Br J Dermatol 2:47–51CrossRef Roewert-Huber J, Lange-Asschenfeldt B, Stockfleth E, Kerl H (2007) Epidemiology and aetiology of basal cell carcinoma. Br J Dermatol 2:47–51CrossRef
2.
Zurück zum Zitat Peikert JM (2011) Prospective trial of curettage and cryosurgery in the management of non-facial, superficial, and minimally invasive basal and squamous cell carcinoma. Int J Dermatol 50:1135–1138PubMedCrossRef Peikert JM (2011) Prospective trial of curettage and cryosurgery in the management of non-facial, superficial, and minimally invasive basal and squamous cell carcinoma. Int J Dermatol 50:1135–1138PubMedCrossRef
3.
Zurück zum Zitat Roenigk RK, Ratz JK, Bailin PL, Wheeland RG (1984) Trends in the presentation of BCC. J Dermatol Surg Oncol 12:860–865 Roenigk RK, Ratz JK, Bailin PL, Wheeland RG (1984) Trends in the presentation of BCC. J Dermatol Surg Oncol 12:860–865
4.
Zurück zum Zitat Carlson KC, Connolly SM, Winkelmann RK (1994) Basal cell carcinoma on the lower extremity. J Dermatol Surg Oncol 20:258–259PubMed Carlson KC, Connolly SM, Winkelmann RK (1994) Basal cell carcinoma on the lower extremity. J Dermatol Surg Oncol 20:258–259PubMed
5.
Zurück zum Zitat Giles GG, Marks R, Foley P (1988) Incidence of non-melanocytic skin cancer treated in Australia. Br Med J 296:13–17CrossRef Giles GG, Marks R, Foley P (1988) Incidence of non-melanocytic skin cancer treated in Australia. Br Med J 296:13–17CrossRef
6.
Zurück zum Zitat Scrivener Y, Grosshans E, Cribier B (2002) Variations of BCC according to gender, age, location and histopathological subtype. Br J Dermatol 147:41–47PubMedCrossRef Scrivener Y, Grosshans E, Cribier B (2002) Variations of BCC according to gender, age, location and histopathological subtype. Br J Dermatol 147:41–47PubMedCrossRef
7.
Zurück zum Zitat Betti R, Radaelli G, Mussino F, Menni S, Crosti C (2009) Anatomic location and histopathologic subtype of BCC in adults younger than 40 or 90 and older: any difference? Dermatol Surg 35:201–206PubMedCrossRef Betti R, Radaelli G, Mussino F, Menni S, Crosti C (2009) Anatomic location and histopathologic subtype of BCC in adults younger than 40 or 90 and older: any difference? Dermatol Surg 35:201–206PubMedCrossRef
8.
Zurück zum Zitat Wang Y, Li J, Xu YW, Buaijiaer HS, Yang JG, Yuan H, Hu DY (2009) Prevalence of peripheral arterial disease and correlative risk factors among natural population in China. Zhonghua Xin Xue Guan Bing Za Zhi 37:1127–1131PubMed Wang Y, Li J, Xu YW, Buaijiaer HS, Yang JG, Yuan H, Hu DY (2009) Prevalence of peripheral arterial disease and correlative risk factors among natural population in China. Zhonghua Xin Xue Guan Bing Za Zhi 37:1127–1131PubMed
9.
Zurück zum Zitat Mani R, Yarde S, Edmonds M (2011) Prevalence of deep venous incompetence and microvascular abnormalities in patients with diabetes mellitus. Int J Low Extrem Wounds 10:75–79PubMedCrossRef Mani R, Yarde S, Edmonds M (2011) Prevalence of deep venous incompetence and microvascular abnormalities in patients with diabetes mellitus. Int J Low Extrem Wounds 10:75–79PubMedCrossRef
10.
Zurück zum Zitat Har-Shai Y, Amar M, Sabo E (2003) Intralesional cryotherapy for enhancing the involution of hypertrophic scars and keloids. Plast Reconstr Surg 111:1841–1852PubMedCrossRef Har-Shai Y, Amar M, Sabo E (2003) Intralesional cryotherapy for enhancing the involution of hypertrophic scars and keloids. Plast Reconstr Surg 111:1841–1852PubMedCrossRef
11.
Zurück zum Zitat Har-shai Y, Dujovny E, Rohde E, Zouboulis CC (2007) Effect of skin surface temperature on skin pigmentation during contact and intralesional cryosurgery of keloids. J Eur Acad Dermatol Venereol 21:191–198PubMedCrossRef Har-shai Y, Dujovny E, Rohde E, Zouboulis CC (2007) Effect of skin surface temperature on skin pigmentation during contact and intralesional cryosurgery of keloids. J Eur Acad Dermatol Venereol 21:191–198PubMedCrossRef
12.
Zurück zum Zitat Har-Shai Y, Sabo E, Rohde E, Hyams M, Assaf C, Zouboulis CC (2006) Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: a new clinical approach supported by experimental studies. Wound Repair Regen 14:18–27PubMedCrossRef Har-Shai Y, Sabo E, Rohde E, Hyams M, Assaf C, Zouboulis CC (2006) Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: a new clinical approach supported by experimental studies. Wound Repair Regen 14:18–27PubMedCrossRef
13.
Zurück zum Zitat Har-Shai Y, Brown W, Labbé D, Dompmartin A, Goldine I, Gil T, Mettanes I, Pallua N (2008) Intralesional cryosurgery for the treatment of hypertrophic scars and keloids following aesthetic surgery: the results of a prospective observational study. Int J Low Extrem Wounds 7:169–175PubMedCrossRef Har-Shai Y, Brown W, Labbé D, Dompmartin A, Goldine I, Gil T, Mettanes I, Pallua N (2008) Intralesional cryosurgery for the treatment of hypertrophic scars and keloids following aesthetic surgery: the results of a prospective observational study. Int J Low Extrem Wounds 7:169–175PubMedCrossRef
14.
Zurück zum Zitat Har-Shai Y, Brown W, Pallua N, Zouboulis CC (2010) Intralesionl cryosurgery for the treatment of hypertrophic scars and keloids (letter). Plast Reconst Surg 126:1798–1800PubMed Har-Shai Y, Brown W, Pallua N, Zouboulis CC (2010) Intralesionl cryosurgery for the treatment of hypertrophic scars and keloids (letter). Plast Reconst Surg 126:1798–1800PubMed
15.
Zurück zum Zitat Har-Shai Y, Mettanes I, Genin O, Spector I, Pines M (2010) Keloid histopathology after intralesional cryoneedle treatment. J Eur Acad Dermatol Venereol 25:1027–36APubMedCrossRef Har-Shai Y, Mettanes I, Genin O, Spector I, Pines M (2010) Keloid histopathology after intralesional cryoneedle treatment. J Eur Acad Dermatol Venereol 25:1027–36APubMedCrossRef
16.
Zurück zum Zitat Mirmovich O, Gil T, Lavi I, Goldine I, Mettanes I, Har-Shai Y (2012) Pain evaluation and control during and following the treatment of hypertrophic scars and keloids employing contact and intralesional cryosurgery-a preliminary study. J Eur Acad Dermatol Venereol (in press) Mirmovich O, Gil T, Lavi I, Goldine I, Mettanes I, Har-Shai Y (2012) Pain evaluation and control during and following the treatment of hypertrophic scars and keloids employing contact and intralesional cryosurgery-a preliminary study. J Eur Acad Dermatol Venereol (in press)
17.
Zurück zum Zitat Kuflik EG (2004) Cryosurgery for skin cancer: 30-year experience and cure rates. Dermatol Surg 30:297–300PubMedCrossRef Kuflik EG (2004) Cryosurgery for skin cancer: 30-year experience and cure rates. Dermatol Surg 30:297–300PubMedCrossRef
18.
Zurück zum Zitat Soanes WA, Albin RJ, Gonder MJ (1970) Remission of metastatic lesions following cryosurgery in prostatic cancer: immunologic considerations. J Urol 140:154–159 Soanes WA, Albin RJ, Gonder MJ (1970) Remission of metastatic lesions following cryosurgery in prostatic cancer: immunologic considerations. J Urol 140:154–159
19.
Zurück zum Zitat Joosten JJ, Muijen GN, Wobbes MJ, Ruers TJ (2001) In vivo destruction of tumor tissue by cryoablation can induce inhibitions of secondary tumor growth: an experimental study. Cryobiology 42:49–58PubMedCrossRef Joosten JJ, Muijen GN, Wobbes MJ, Ruers TJ (2001) In vivo destruction of tumor tissue by cryoablation can induce inhibitions of secondary tumor growth: an experimental study. Cryobiology 42:49–58PubMedCrossRef
20.
Zurück zum Zitat Messeguer F, Serra-Guillen C, Echeverria B, Requena C, Sanmartin O, Llombart C, Guillen C, Nagore E (2012) A pilot study of clinical efficacy of imiquimod and cryotherapy for the treatment of BCC with incomplete response to imiquimod. J Eur Acad Dermatol Venereol (in press) Messeguer F, Serra-Guillen C, Echeverria B, Requena C, Sanmartin O, Llombart C, Guillen C, Nagore E (2012) A pilot study of clinical efficacy of imiquimod and cryotherapy for the treatment of BCC with incomplete response to imiquimod. J Eur Acad Dermatol Venereol (in press)
21.
Zurück zum Zitat Andrews MD (2004) Cryosurgery for common skin conditions. Am Fam Physician 69:2365–2372PubMed Andrews MD (2004) Cryosurgery for common skin conditions. Am Fam Physician 69:2365–2372PubMed
22.
Zurück zum Zitat Weshahy AH (1993) Intralesional cryosurgery, a new technique using cryoneedles. J Dermatol Surg Oncol 19:123–126PubMed Weshahy AH (1993) Intralesional cryosurgery, a new technique using cryoneedles. J Dermatol Surg Oncol 19:123–126PubMed
23.
Zurück zum Zitat Baust JC, Gage AA (2005) The molecular basis of cryosurgery. Br J Urol Int 95:1187–1191CrossRef Baust JC, Gage AA (2005) The molecular basis of cryosurgery. Br J Urol Int 95:1187–1191CrossRef
Metadaten
Titel
Intralesional cryosurgery for the treatment of basal cell carcinoma in an elderly patient
verfasst von
Yaron Har-Shai
Lior Har-Shai
Miriam Lurie
Edmond Sabo
Publikationsdatum
01.08.2012
Verlag
Springer-Verlag
Erschienen in
European Journal of Plastic Surgery / Ausgabe 8/2012
Print ISSN: 0930-343X
Elektronische ISSN: 1435-0130
DOI
https://doi.org/10.1007/s00238-012-0692-4

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