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01.12.2019 | Case report | Ausgabe 1/2019 Open Access

World Journal of Surgical Oncology 1/2019

Intrapancreatic accessory spleen false positive to 68Ga-Dotatoc: case report and literature review

World Journal of Surgical Oncology > Ausgabe 1/2019
Francesco Lancellotti, Luca Sacco, Saverio Cerasari, Vittoria Bellato, Simone Cicconi, Antonio Ciardi, Edoardo Maria Muttillo, Tiziana Feola, Roberto Caronna, Piero Chirletti
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Intrapancreatic accessory spleen (IPAS) is an uncommon finding of pancreatic mass. Differential diagnosis with pancreatic tumor, especially with non-functional neuroendocrine tumor (NF-NET), may be very hard and sometimes it entails unnecessary surgery. A combination of CT scan, MRI, and nuclear medicine can confirm the diagnosis of IPAS. 68-Ga-Dotatoc PET/CT is the gold standard in NET diagnosis and it can allow to distinguish between IPAS and NET.

Case presentation

A 69-year-old man was admitted to our hospital for an incidental nodule in the tail of the pancreas with focal uptake of 68-Ga-dotatate at PET/CT. NET was suspected and open distal splenopancreatectomy was performed. Pathologic examination revealed an IPAS.


This is the second IPAS case in which a positive 68Ga-Dotatoc uptake led to a false diagnosis of pancreatic NET. Here is a proposal of a literature review.
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