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01.12.2014 | Case report | Ausgabe 1/2014 Open Access

Journal of Medical Case Reports 1/2014

Intraparenchymal meningioma mimicking cavernous malformation: a case report and review of the literature

Journal of Medical Case Reports > Ausgabe 1/2014
Senol Jadik, Alexandru C Stan, Uwe Dietrich, Terttu A Pietilä, Alaa Eldin Elsharkawy
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1752-1947-8-467) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

SJ carried out the design of the study and drafted the manuscript. ACS carried out the neuropathological examination and drafted the pathology section of the manuscript. UW carried out the neuroradiological assessment. TAP conceived of the study, participated in its design and coordination, and helped to draft the manuscript. AEE conceived of the study, participated in its design and coordination, helped to draft the manuscript, and carried out the literature review and discussion section. All authors read and approved the final manuscript.



A primary intraparenchymal meningioma located in the subcortical region of the brain without a dural attachment is extremely rare. To the best of our knowledge, this is the first report showing that meningioma can mimic cavernous malformations.

Case presentation

We present the case of a 42-year-old German man who presented to our institution with seizure. Both computed tomography and magnetic resonance imaging scans showed characters of an intra-axial subcortical lesion with a ‘popcorn’ appearance and hemosiderin deposits in the right parietal lobe. The initial diagnosis was cavernous malformation. Intraoperatively, the lesion presented as a subcortical mass that had no connection to the dura or the ventricle. The histological diagnosis showed a WHO Grade 1 ‘raddled’ psammomatous meningioma with extensive metaplastic ossification. A literature review of 29 cases of intraparenchymal meningiomas regarding their clinical presentations, location and management was performed.


Meningiomas can be found in any region of the brain with and without dural attachment. Intraparenchymal meningiomas can have multiple entities mimicking their presentation. Caution must be used regarding the preoperative differential diagnosis.

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