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Breast Cancer Research

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01.12.2006 | Commentary

Intrauterine exposures, pregnancy estrogens and breast cancer risk: where do we currently stand?

verfasst von: Pagona Lagiou

Erschienen in: Breast Cancer Research | Ausgabe 6/2006

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Abstract

Since 1990, when a hypothesis on intrauterine influences on breast cancer risk was published, several studies have provided supportive, indirect evidence by documenting associations of birth weight and other correlates of the prenatal environment with breast cancer risk in offspring. Recent results from a unique cohort of women with documented exposure to diethylstilbestrol in utero have provided direct evidence in support of a potential role of pregnancy oestrogens on breast cancer risk in offspring.

Rothman KJ, MacMahon B, Lin TM, Lowe CR, Mirra AP, Ravnihar B, Salber EJ, Trichopoulos D, Yuasa S: Maternal age and birth rank of women with breast cancer. J Natl Cancer Inst. 1980, 65: 719-722.PubMed

Le Marchand L, Kolonel LN, Myers BC, Mi MP: Birth characteristics of premenopausal women with breast cancer. Br J Cancer. 1988, 57: 437-439.CrossRefPubMedPubMedCentral

Trichopoulos D: Hypothesis: does breast cancer originate in utero?. Lancet. 1990, 335: 939-940. 10.1016/0140-6736(90)91000-Z.CrossRefPubMed

Trichopoulos D, Lipman R: Mammary gland mass and breast cancer risk. Epidemiology. 1992, 3: 523-526.CrossRefPubMed

Adami H-O, Signorello LB, Trichopoulos D: Towards an understanding of breast cancer etiology. Semin Cancer Biol. 1998, 8: 255-262. 10.1006/scbi.1998.0077.CrossRefPubMed

Trichopoulos D, Lagiou P, Adami HO: Towards an integrated model for breast cancer etiology: the crucial role of the number of mammary tissue-specific stem cells. Breast Cancer Res. 2005, 7: 13-17. 10.1186/bcr966.CrossRefPubMed

Michels KB, Trichopoulos D, Robins JM, Rosner BA, Manson JE, Hunter DJ, Colditz GA, Hankinson SE, Speizer FE, Willett WC: Birth weight as a risk factor for breast cancer. Lancet. 1996, 348: 1542-1546. 10.1016/S0140-6736(96)03102-9.CrossRefPubMed

Vatten LJ, Maehle BO, Lund Nilsen TI, Tretli S, Hsieh C-c, Trichopoulos D, Stuver SO: Birth weight as a predictor of breast cancer: a case-control study in Norway. Br J Cancer. 2002, 86: 89-91. 10.1038/sj.bjc.6600011.CrossRefPubMedPubMedCentral

Ahlgren M, Sorensen T, Wohlfahrt J, Haflidadottir A, Holst C, Melbye M: Birth weight and risk of breast cancer in a cohort of 106,504 women. Int J Cancer. 2003, 107: 997-1000. 10.1002/ijc.11481.CrossRefPubMed

10.

Cerhan JR, Kushi LH, Olson JE, Rich SS, Zheng W, Folsom AR, Sellers TA: Twinship and risk of postmenopausal breast cancer. J Natl Cancer Inst. 2000, 92: 261-265. 10.1093/jnci/92.3.261.CrossRefPubMed

11.

Ekbom A, Hsieh CC, Lipworth L, Adami HO, Trichopoulos D: Intrauterine environment and breast cancer risk in women: a population-based study. J Natl Cancer Inst. 1997, 89: 71-76. 10.1093/jnci/89.1.71.CrossRefPubMed

12.

Hsieh C-c, Tzonou A, Trichopoulos D: Birth order and breast cancer risk. Cancer Causes Control. 1991, 2: 95-98. 10.1007/BF00053127.CrossRefPubMed

13.

Hatch EE, Palmer JR, Titus-Ernstoff L, Noller KL, Kaufman RH, Mittendorf R, Robboy SJ, Hyer M, Cowan CM, Adam E, et al: Cancer risk in women exposed to diethylstilbestrol in utero. JAMA. 1998, 280: 630-634. 10.1001/jama.280.7.630.CrossRefPubMed

14.

Palmer JR, Hatch EE, Rosenberg CL, Hartge P, Kaufman RH, Titus-Ernstoff L, Noller KL, Herbst AL, Rao RS, Troisi R, et al: Risk of breast cancer in women exposed to diethylstilbestrol in utero: prelimiinary results (United States). Cancer Causes Control. 2002, 13: 753-758. 10.1023/A:1020254711222.CrossRefPubMed

15.

Palmer JR, Wise LA, Hatch EE, Troisi R, Titus-Ernstoff L, Strohsnitter W, Kaufman R, Herbst AL, Noller KL, Hyer M, et al: Prenatal diethylstilbestrol exposure and risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 2006, 15: 1509-1514. 10.1158/1055-9965.EPI-06-0109.CrossRefPubMed

16.

Herbst AL, Ulfelder H, Poskanzer DC: Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumor appearance in young women. N Engl J Med. 1971, 284: 878-881.CrossRefPubMed

17.

Loman N, Johannsson O, Kristoffersson U, Olsson H, Borg A: Family history of breast and ovarian cancers and BRCA1 and BRCA2 mutations in a population-based series of early-onset breast cancer. J Natl Cancer Inst. 2001, 93: 1215-1223. 10.1093/jnci/93.16.1215.CrossRefPubMed

18.

Baik I, Becker PS, DeVito WJ, Lagiou P, Ballen K, Quesenberry PJ, Hsieh CC: Stem cells and prenatal origin of breast cancer. Cancer Causes Control. 2004, 15: 517-530. 10.1023/B:CACO.0000036450.06092.ce.CrossRefPubMed

19.

DeWaard F, Trichopoulos D: A unifying concept of the aetiology of breast cancer. Int J Cancer. 1988, 41: 666-669.CrossRef

20.

Baik I, Devito WJ, Ballen K, Becker PS, Okulicz W, Liu Q, Delpapa E, Lagiou P, Sturgeon S, Trichopoulos D, et al: Association of fetal hormone levels with stem cell potential: evidence for early life roots of human cancer. Cancer Res. 2005, 65: 358-363.PubMed

Titel: Intrauterine exposures, pregnancy estrogens and breast cancer risk: where do we currently stand?
verfasst von: Pagona Lagiou
Publikationsdatum: 01.12.2006
Verlag: BioMed Central
Erschienen in: Breast Cancer Research / Ausgabe 6/2006
Elektronische ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr1615

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