What is Known:
• Oral paracetamol has been judged as effective as oral ibuprofen for PDA closure in the preterm.
• To date, only a handful of non-randomized studies exist to support the effectiveness of i.v. paracetamol in PDA closure.
What is New:
• Our observations confirm the clinical efficacy of i.v. paracetamol for PDA closure in a very low birth weight (VLBW)/extremely low birth weight (ELBW) preterm population.
• Gestational age and CRIB score emerge as independent predictors of PDA closure.