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Erschienen in: Indian Journal of Hematology and Blood Transfusion 3/2018

26.10.2017 | Short Communication

Invasive Fungal Infections in Acute Promyelocytic Leukemia on Dual Differentiating Agents: Real World Data

verfasst von: Uday Yanamandra, Parathan Karunakaran, Alka Khadwal, Gaurav Prakash, Deepesh Lad, Shano Naseem, Neelam Varma, Arunaloke Chakrabarti, Subhash Varma, Pankaj Malhotra

Erschienen in: Indian Journal of Hematology and Blood Transfusion | Ausgabe 3/2018

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Abstract

Invasive fungal infection (IFI) in patients with acute promyelocytic leukemia (APL) is a common phenomenon in developing countries. In a systematic study (Dual Inducing Differentiating agents—Indian Trial: DID-IT) using dual differentiating agents (ATO and ATRA) in 98 APL patients at our center we report 18.3% incidence of IFI (n-18). Among all cases of IFI three were definitive, 14 were probable and one was possible IFI. We conclude that incidence of IFI in APL is affected by environmental and therapy related factors and mere usage of dual differentiating agents need not necessarily decrease the incidence of fungal infections.
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Metadaten
Titel
Invasive Fungal Infections in Acute Promyelocytic Leukemia on Dual Differentiating Agents: Real World Data
verfasst von
Uday Yanamandra
Parathan Karunakaran
Alka Khadwal
Gaurav Prakash
Deepesh Lad
Shano Naseem
Neelam Varma
Arunaloke Chakrabarti
Subhash Varma
Pankaj Malhotra
Publikationsdatum
26.10.2017
Verlag
Springer India
Erschienen in
Indian Journal of Hematology and Blood Transfusion / Ausgabe 3/2018
Print ISSN: 0971-4502
Elektronische ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-017-0894-9

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