10.06.2024 | ASO Research Letter
Investigating Differences in Pancreatic Ductal Adenocarcinoma Mutational Profiles Across Racial and Ethnic Groups: A Lack of Diversity Clouds the Picture
verfasst von:
Judy Li, MD, Adam Geffner, BA, Noah A. Cohen, MD
Erschienen in:
Annals of Surgical Oncology
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Ausgabe 10/2024
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Excerpt
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer death in the United States.
1 The common genetic drivers of PDAC have been reported, and matching therapies to an individual’s tumor mutation profile is a focus of ongoing research.
2,3 Patients from underrepresented racial and ethnic groups demonstrate disparities in outcomes.
4,5 We investigated whether underlying differences in PDAC tumor mutational profiles exist across racial and ethnic groups. …