Investigational New Drugs

In Vitro Binding and Partitioning of Irinotecan (CPT-11) and its Metabolite, SN-38, in Human Blood

Olivier Combes, Jérôme Barré, Jean-Claude Duché, Laurent Vernillet, Yves Archimbaud, Michael P. Marietta, Jean-Paul Tillement, Saïk Urien

Development of Target-Based Antineoplastic Agents

Walter M. Stadler, Mark J. Ratain

Advanced Non-Small Cell Lung Carcinoma: The Emerging Role of Docetaxel

Corey J. Langer

Gemcitabine in Non-Small Cell Lung Cancer (NSCLC)

Christian Manegold, Petr Zatloukal, Kurt Krejcy, Johannes Blatter

Current Approaches and Future Strategies for Pancreatic Carcinoma

Robert A. Wolff, Paul Chiao, Renato Lenzi, Peter W.T. Pisters, Jeffrey E. Lee, Nora A. JanJan, Christopher H. Crane, Douglas B. Evans, James L. Abbruzzese

Promising Approaches in Acute Leukemia

Jorge Cortes, Hagop M. Kantarjian

A Phase I Trial of Cisplatin Plus Decitabine, a New DNA-Hypomethylating Agent, in Patients with Advanced Solid Tumors and a Follow-Up Early Phase II Evaluation in Patients with Inoperable Non-Small Cell Lung Cancer

G. Schwartsmann, H. Schunemann, C.N.F. Gorini, A.F. Ferreira Filho, C. Garbino, G. Sabini, I. Muse, L DiLeone, D.R. Mans

Instructions to Authors