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Investigational New Drugs

Ausgabe 1/2003

Inhalt (13 Artikel)

Discovery and Preclinical Antitumor Efficacy Evaluations of LY32262 and LY33169

Thomas H. Corbett, Kathryn White, Lisa Polin, Juiwanna Kushner, Jennifer Paluch, Chuan Shih, Cora Sue Grossman

A Phase I Clinical Trial of Spicamycin Derivative KRN5500 (NSC 650426) Using a Phase I Accelerated Titration “2B” Design

S.M. Gadgeel, R.R. Boinpally, L.K. Heilbrun, A. Wozniak, V. Jain, B. Redman, M. Zalupski, R. Wiegand, R. Parchment, P.M. LoRusso

A Phase I and Pharmacologic Study of Pyrazoloacridine and Cisplatin in Patients with Advanced Cancer

E. Claire Dees, Eric K. Rowinsky, Dennis A. Noe, Seamus O'Reilly, Alex A. Adjei, Kathy Elza-Brown, Ross C. Donehower

Phase I and Pharmacologic Study of the Human DNA Methyltransferase Antisense Oligodeoxynucleotide MG98 given as a 21-day Continuous Infusion Every 4 Weeks

Alison J. Davis, Karen A. Gelmon, Lillian L. Siu, Malcolm J. Moore, Carolyn D. Britten, Nisha Mistry, Henry Klamut, Susan D'Aloisio, Martha MacLean, Nancy Wainman, Debbie Ayers, Patricia Firby, Jeffrey M. Besterman, Gregory K. Reid, Elizabeth A. Eisenhauer

Phase II Trial of Antiepidermal Growth Factor Receptor Antibody C225 in Patients with Advanced Renal Cell Carcinoma

Robert J. Motzer, Robert Amato, Mary Todd, Wen-J Poo Hwu, Roger Cohen, Jose Baselga, Hyman Muss, Michael Cooper, Richard Yu, Michelle S. Ginsberg, Michael Needle

A Phase II Study of Rebeccamycin Analog NSC 655649 in Patients with Metastatic Colorectal Cancer

Sanjay Goel, Scott Wadler, Anthony Hoffman, Fabio Volterra, Cheryl Baker, Elliot Nazario, Percy Ivy, Alyson Silverman, Sridhar Mani

Current Approaches to Novel Therapeutics in Pancreatic Cancer

Corina E. Akerele, Irina Rybalova, Howard L. Kaufman, Sridhar Mani

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