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Zeitschrift

Investigational New Drugs

Investigational New Drugs 4/2006

Ausgabe 4/2006

Inhaltsverzeichnis ( 13 Artikel )

01.07.2006 | Preclinical Studies | Ausgabe 4/2006 Open Access

The Wnt-dependent signaling pathways as target in oncology drug discovery

Nico Janssens, Michel Janicot, Tim Perera

01.07.2006 | Preclinical Studies | Ausgabe 4/2006

Population pharmacokinetics and bioavailability of motexafin gadolinium (Xcytrin®) in CD1 mice following intravenous and intraperitoneal injection

Boswell GW, DR Miles, PA Thiemann, M Mesfin

01.07.2006 | Preclinical Studies | Ausgabe 4/2006

Binding of gefitinib, an inhibitor of epidermal growth factor receptor-tyrosine kinase, to plasma proteins and blood cells: in vitro and in cancer patients

Jing Li, Julie Brahmer, Wells Messersmith, Manuel Hidalgo, Sharyn D. Baker

01.07.2006 | Phase I Studies | Ausgabe 4/2006

A phase I Study with oral SU5416 in patients with advanced solid tumors: A drug inducing its clearance

Marc Salzberg, Miklos Pless, Christoph Rochlitz, Klara Ambrus, Paul Scigalla, Richard Herrmann

01.07.2006 | Phase I Studies | Ausgabe 4/2006

A phase I study of flavopiridol and docetaxel

Basil F. El-Rayes, Shirish Gadgeel, Ralph Parchment, Patricia Lorusso, Philip A. Philip

01.07.2006 | Phase I Studies | Ausgabe 4/2006

A phase I and pharmacokinetic study of irofulven and cisplatin administered in a 30-min infusion every two weeks to patients with advanced solid tumors

Werner Hilgers, Sandrine Faivre, Stéphanie Chieze, Jérôme Alexandre, François Lokiec, François Goldwasser, Eric Raymond, Carmen Kahatt, Abdelkrim Taamma, Garry Weems, John R. MacDonald, Jean-Louis Misset, Esteban Cvitkovic

01.07.2006 | Phase I Studies | Ausgabe 4/2006

Phase I trial of thalidomide and Interleukin-2 in patients with metastatic renal cell carcinoma

Thomas Olencki, Sareena Malhi, Tarek Mekhail, Robert Dreicer, Paul Elson, Laura Wood, Ronald M. Bukowski

01.07.2006 | Phase I Studies | Ausgabe 4/2006

A phase I clinical and pharmacokinetic study of CS-682 administered orally in advanced malignant solid tumors

Thierry Delaunoit, Patrick A. Burch, Joel M. Reid, John K. Camoriano, Tomowo Kobayash, Theodore A. Braich, Judith S. Kaur, Joseph Rubin, Charles Erlichman

01.07.2006 | Phase II Studies | Ausgabe 4/2006

Phase II trial of R115777 (NSC #70818) in patients with advanced colorectal cancer: A Southwest Oncology Group study

Robert P. Whitehead, Sheryl McCoy, John S. Macdonald, Saul E. Rivkin, Marcus A. Neubauer, Shaker R. Dakhil, Heinz-Josef Lenz, Michael S. Tanaka, James L. Abbruzzese

01.07.2006 | Phase II Studies | Ausgabe 4/2006

A phase II study of chloroquinoxaline sulfonamide (CQS) in patients with metastatic colorectal carcinoma (MCRC)

Tanios S. Bekaii-Saab, Amir Mortazavi, Lee G. Hicks, Mark Zalupski, Robert J. Pelley, Kenneth K. Chan, Eric H. Kraut

01.07.2006 | Phase II Studies | Ausgabe 4/2006

SarCNU in recurrent or metastatic colorectal cancer: A phase II study of the National Cancer Institute of Canada Clinical Trials Group

R. P. Wong, T. Baetz, M. J. Krahn, J. Biagi, N. Wainman, E. Eisenhauer

01.07.2006 | Phase II Studies | Ausgabe 4/2006

A multi-center phase II study of sequential paclitaxel and bryostatin-1 (NSC 339555) in patients with untreated, advanced gastric or gastroesophageal junction adenocarcinoma

Jaffer A. Ajani, Yixing Jiang, Josephine Faust, Baochong B. Chang, Linus Ho, James C. Yao, Steven Rousey, Shaker Dakhil, Richard C. Cherny, Catherine Craig, Archie Bleyer

01.07.2006 | Phase II Studies | Ausgabe 4/2006

Phase II study of rubitecan, an oral camptothecin in patients with advanced colorectal cancer who have failed previous 5-fluorouracil based chemotherapy

Hitendra Patel, Ronald Stoller, Miklos Auber, Douglas Potter, Chao Cai, William Zamboni, Gauri Kiefer, Khalid Matin, Amy Schmotzer, Ramesh K. Ramanathan

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