Skip to main content

Investigational New Drugs

Ausgabe 4/2007

Inhalt (15 Artikel)

PRECLINICAL STUDIES

Evaluation of ABT-751 against childhood cancer models in vivo

Christopher L. Morton, Edward G. Favours, Kimberly S. Mercer, Claire R. Boltz, Jeri Carol Crumpton, Chandra Tucker, Catherine A. Billups, Peter J. Houghton

PRECLINICAL STUDIES

Pharmacological profiling of novel non-COX-inhibiting indole-pyran analogues of etodolac reveals high solid tumour activity of SDX-308 in vitro

Elin Lindhagen, Linda Rickardson, Gary Elliott, Lorenzo Leoni, Peter Nygren, Rolf Larsson, Anna Åleskog

PRECLINICAL STUDIES

Taurolidine: a novel anti-neoplastic agent induces apoptosis of osteosarcoma cell lines

Denise K. Walters, Roman Muff, Bettina Langsam, Philipp Gruber, Walter Born, Bruno Fuchs

PRECLINICAL STUDIES

A thermally targeted elastin-like polypeptide-doxorubicin conjugate overcomes drug resistance

Gene L. Bidwell III, Aisha N. Davis, Izabela Fokt, Waldemar Priebe, Drazen Raucher

Open Access PHASE I STUDIES

Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry

J. H. Beumer, R. C. Garner, M. B. Cohen, S. Galbraith, G. F. Duncan, T. Griffin, J. H. Beijnen, J. H. M. Schellens

Phase I Studies

A phase I trial of BMS-247550 (NSC# 710428) and gemcitabine in patients with advanced solid tumors

Martee L. Hensley, Don Dizon, Felicia Derosa, Ennapadam Venkatraman, Paul Sabbatini, Dennis S. Chi, Jakob Dupont, A. Dimitrios Colevas, David Spriggs, Carol Aghajanian

Phase I Studies

Pro-apoptotic activity of imidazole derivatives mediated by up-regulation of Bax and activation of CAD in Ehrlich Ascites Tumor cells

C. Anil Kumar, Shankar Jayarama, Basappa, Bharathi P. Salimath, Kanchugarakoppal S. Rangappa

PHASE I STUDIES

Erlotinib and vinorelbine in advanced malignant solid tumors: a phase I study

Angela M Davies, Cheryl Ho, Paul J Hesketh, Laurel A Beckett, Primo N Lara Jr, Derick HM Lau, David R Gandara

Erratum

A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomes

Quincy S. C. Chu, Bahram Forouzesh, Samira Syed, Monica Mita, Garry Schwartz, Joshua Cooper, Janet Curtright, Eric K. Rowinsky

Phase II Studies

A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas

Quincy S. C. Chu, Bahram Forouzesh, Samira Syed, Monica Mita, Garry Schwartz, Joshua Copper, Janet Curtright, Eric K. Rowinsky

Phase II Studies

Phase II study of CT-2103 as first- or second-line chemotherapy in patients with metastatic breast cancer: unexpected incidence of hypersensitivity reactions

Nancy U. Lin, Leroy M. Parker, Steven E. Come, Harold J. Burstein, Margaret Haldoupis, Nicole Ryabin, Rebecca Gelman, Eric P. Winer, Lawrence N. Shulman

PHASE II STUDIES

Phase II study of amrubicin, 9-amino-anthracycline, in patients with advanced non-small-cell lung cancer: a West Japan Thoracic Oncology Group (WJTOG) study

Koji Takeda, Nobuhide Takifuji, Shunichi Negoro, Kiyoyuki Furuse, Shinichiro Nakamura, Yoshiki Takada, Takanobu Hoso, Shinichi Hayasaka, Takashi Nakano, Jun Araki, Hiroshi Senba, Fumiyuki Iwami, Yasufumi Yamaji, Masahiro Fukuoka, Harumichi Ikegami

PHASE II STUDIES

A randomised phase II study of OSI-7904L versus 5-fluorouracil (FU)/leucovorin (LV) as first-line treatment in patients with advanced biliary cancers

T. Ciuleanu, M. Diculescu, N. M. Hoepffner, J. Trojan, V. Sailer, M. Zalupski, T. Herrmann, A. Roth, J. Chick, K. Brock, D. Albert, P. A. Philip

SHORT REPORT

Simple, mammalian cell-based assay for identification of inhibitors of the Erk MAP kinase pathway

Pavel Krejci, Katerina Pejchalova, William R. Wilcox

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.