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Erschienen in: International Journal of Hematology 1/2018

05.12.2017 | Progress in Hematology

Iron metabolism and related diseases: an overview

verfasst von: Hideo Harigae

Erschienen in: International Journal of Hematology | Ausgabe 1/2018

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Excerpt

Iron is an essential metal not only for oxygen delivery but also for cellular processes, including ATP production and DNA biosynthesis. Iron is utilized by the semi-closed system and is not actively excreted from the body. This system is advantageous, because it prevents the shortage of this important metal and is not influenced by the environmental status. In this system, the iron supply depends on a narrow gate at the duodenum, and iron accumulates in the organ once it is overloaded. These specificities of iron metabolism lead to the high frequency of iron deficiency anemia (IDA) among young females and secondary hemochromatosis due to blood transfusion. …
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Metadaten
Titel
Iron metabolism and related diseases: an overview
verfasst von
Hideo Harigae
Publikationsdatum
05.12.2017
Verlag
Springer Japan
Erschienen in
International Journal of Hematology / Ausgabe 1/2018
Print ISSN: 0925-5710
Elektronische ISSN: 1865-3774
DOI
https://doi.org/10.1007/s12185-017-2384-0

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