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Erschienen in: Current Oral Health Reports 4/2019

08.12.2019 | Modern Approaches to Endodontics (S Kim and B Karabucak, Section Editors)

Irrigation in Endodontics: a Review

verfasst von: Sarah Bukhari, Alaa Babaeer

Erschienen in: Current Oral Health Reports | Ausgabe 4/2019

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Abstract

Purpose of Review

The purpose of this chapter was to review progress in the endodontic irrigation and advances in disinfection process and their clinical implication.

Recent Findings

This review shed the light on the culturing techniques shortcomings and the complexity of the root canal infection both anatomically and microbiologically. It also discusses in depth the most widely used endodontic irrigants, their antimicrobial efficacy, safety, advantages, and disadvantages. Irrigation issues to discuss are not merely centered on which antimicrobial solution to use, but also its method of delivery, preferably to all parts of the complex anatomy of root canals, bearing in mind the complex features of the offending microbial biofilm. The new direction has been toward developing a reliable delivery system to ensure thorough disinfection to the inaccessible areas of the root canal system such as passive ultrasonic irrigation, XP Endo finisher, Endo Vac, and Gentlewave.

Summary

To date, sodium hypochlorite (NaOCl) remains the gold standard of endodontic irrigants, due to its tissue dissolving capacity exhibited by no other. However, it still falls short of completely rendering root canal bacteria free. Moreover, its toxicity is detrimental when extruded beyond the apex. In this review, potential complementary irrigation solutions are discussed along with adjunctive irrigation techniques for safer and more effective delivery of the irrigation aiming to perfect disinfection of root canal.
Literatur
1.
Zurück zum Zitat Kakehashi S, Stanley HR, Fitzgerald RJ. The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats. Oral Surg Oral Med Oral Pathol. 1965;20:340–9.PubMed Kakehashi S, Stanley HR, Fitzgerald RJ. The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats. Oral Surg Oral Med Oral Pathol. 1965;20:340–9.PubMed
2.
Zurück zum Zitat Siqueira JF, Rôças IN, Ricucci D. Biofilms in endodontic infection. Endodontic Topics. 2010;22:33–49. Siqueira JF, Rôças IN, Ricucci D. Biofilms in endodontic infection. Endodontic Topics. 2010;22:33–49.
3.
Zurück zum Zitat Trope M, Bergenholtz G. Microbiological basis for endodontic treatment: can a maximal outcome be achieved in one visit? Endodontic Topics. 2002;1:40–53. Trope M, Bergenholtz G. Microbiological basis for endodontic treatment: can a maximal outcome be achieved in one visit? Endodontic Topics. 2002;1:40–53.
4.
Zurück zum Zitat Siqueira JF Jr, Rocas IN. Clinical implications and microbiology of bacterial persistence after treatment procedures. J Endod. 2008;34(11):1291–301 e3.PubMed Siqueira JF Jr, Rocas IN. Clinical implications and microbiology of bacterial persistence after treatment procedures. J Endod. 2008;34(11):1291–301 e3.PubMed
5.
Zurück zum Zitat Shuping GB, Orstavik D, Sigurdsson A, Trope M. Reduction of intracanal bacteria using nickel-titanium rotary instrumentation and various medications. J Endod. 2000;26(12):751–5.PubMed Shuping GB, Orstavik D, Sigurdsson A, Trope M. Reduction of intracanal bacteria using nickel-titanium rotary instrumentation and various medications. J Endod. 2000;26(12):751–5.PubMed
6.
Zurück zum Zitat Paque F, Ganahl D, Peters OA. Effects of root canal preparation on apical geometry assessed by micro-computed tomography. J Endod. 2009;35(7):1056–9.PubMed Paque F, Ganahl D, Peters OA. Effects of root canal preparation on apical geometry assessed by micro-computed tomography. J Endod. 2009;35(7):1056–9.PubMed
7.
Zurück zum Zitat Estrela C, Estrela CR, Barbin EL, Spano JC, Marchesan MA, Pecora JD. Mechanism of action of sodium hypochlorite. Braz Dent J. 2002;13(2):113–7.PubMed Estrela C, Estrela CR, Barbin EL, Spano JC, Marchesan MA, Pecora JD. Mechanism of action of sodium hypochlorite. Braz Dent J. 2002;13(2):113–7.PubMed
8.
Zurück zum Zitat Zehnder M, Kosicki D, Luder H, Sener B, Waltimo T. Tissue-dissolving capacity and antibacterial effect of buffered and unbuffered hypochlorite solutions. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2002;94(6):756–62.PubMed Zehnder M, Kosicki D, Luder H, Sener B, Waltimo T. Tissue-dissolving capacity and antibacterial effect of buffered and unbuffered hypochlorite solutions. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2002;94(6):756–62.PubMed
9.
Zurück zum Zitat Portenier I, Waltimo T, Orstavik D, Haapasalo M. The susceptibility of starved, stationary phase, and growing cells of Enterococcus faecalis to endodontic medicaments. J Endod. 2005;31(5):380–6.PubMed Portenier I, Waltimo T, Orstavik D, Haapasalo M. The susceptibility of starved, stationary phase, and growing cells of Enterococcus faecalis to endodontic medicaments. J Endod. 2005;31(5):380–6.PubMed
10.
Zurück zum Zitat Haapasalo HK, Siren EK, Waltimo TMT, Orstavik D, Haapasalo MPP. Inactivation of local root canal medicaments by dentine: an in vitro study. Int Endod J. 2000;33(2):126–31.PubMed Haapasalo HK, Siren EK, Waltimo TMT, Orstavik D, Haapasalo MPP. Inactivation of local root canal medicaments by dentine: an in vitro study. Int Endod J. 2000;33(2):126–31.PubMed
11.
Zurück zum Zitat Pappen FG, Qian W, Aleksejuniene J, Leonardo RD, Leonardo MR, Haapasalo M. Inhibition of sodium hypochlorite antimicrobial activity in the presence of bovine serum albumin. J Endod. 2010;36(2):268–71.PubMed Pappen FG, Qian W, Aleksejuniene J, Leonardo RD, Leonardo MR, Haapasalo M. Inhibition of sodium hypochlorite antimicrobial activity in the presence of bovine serum albumin. J Endod. 2010;36(2):268–71.PubMed
12.
Zurück zum Zitat Goncalves LS, Rodrigues RCV, Andrade CV, Soares RG, Vettore MV. The effect of sodium hypochlorite and chlorhexidine as irrigant solutions for root canal disinfection: a systematic review of clinical trials. J Endod. 2016;42(4):527–32.PubMed Goncalves LS, Rodrigues RCV, Andrade CV, Soares RG, Vettore MV. The effect of sodium hypochlorite and chlorhexidine as irrigant solutions for root canal disinfection: a systematic review of clinical trials. J Endod. 2016;42(4):527–32.PubMed
13.
Zurück zum Zitat Vianna ME, Conrads G, Gomes BPFA, Horz HP. Identification and quantification of Archaea involved in primary endodontic infections. J Clin Microbiol. 2006;44(4):1274–82.PubMedPubMedCentral Vianna ME, Conrads G, Gomes BPFA, Horz HP. Identification and quantification of Archaea involved in primary endodontic infections. J Clin Microbiol. 2006;44(4):1274–82.PubMedPubMedCentral
14.
Zurück zum Zitat Ercan ER, Ozekinci T, Atakul F, Gul K. Antibacterial activity of 2% chlorhexidine gluconate and 5.25% sodium hypochlorite in infected root canal: in vivo study. J Endod. 2004;30(2):84–7.PubMed Ercan ER, Ozekinci T, Atakul F, Gul K. Antibacterial activity of 2% chlorhexidine gluconate and 5.25% sodium hypochlorite in infected root canal: in vivo study. J Endod. 2004;30(2):84–7.PubMed
15.
Zurück zum Zitat Karuvilla JR, Kamath MP. Antimicrobial activity of 2.5% sodium hypochlorite and 0.2% chlorhexidine gluconate separately and combined, as endodontic irrigants. J Endod. 1998;24(7):472–6. Karuvilla JR, Kamath MP. Antimicrobial activity of 2.5% sodium hypochlorite and 0.2% chlorhexidine gluconate separately and combined, as endodontic irrigants. J Endod. 1998;24(7):472–6.
16.
Zurück zum Zitat Rocas IN, Siqueira JF. Comparison of the in vivo antimicrobial effectiveness of sodium hypochlorite and chlorhexidine used as root canal irrigants: a molecular microbiology study. J Endod. 2011;37(2):143–50.PubMed Rocas IN, Siqueira JF. Comparison of the in vivo antimicrobial effectiveness of sodium hypochlorite and chlorhexidine used as root canal irrigants: a molecular microbiology study. J Endod. 2011;37(2):143–50.PubMed
17.
Zurück zum Zitat Gomes BPFA, Martinho FC, Vianna ME. Comparison of 2.5% sodium hypochlorite and 2% chlorhexidine gel on oral bacterial lipopolysaccharide reduction from primarily infected root canals. J Endod. 2009;35(10):1350–3.PubMed Gomes BPFA, Martinho FC, Vianna ME. Comparison of 2.5% sodium hypochlorite and 2% chlorhexidine gel on oral bacterial lipopolysaccharide reduction from primarily infected root canals. J Endod. 2009;35(10):1350–3.PubMed
18.
Zurück zum Zitat Sathorn C, Parashos P, Messer HH. How useful is root canal culturing in predicting treatment outcome? J Endod. 2007;33(3):220–5.PubMed Sathorn C, Parashos P, Messer HH. How useful is root canal culturing in predicting treatment outcome? J Endod. 2007;33(3):220–5.PubMed
19.
Zurück zum Zitat Pinheiro ET, Candeiro GT, Teixeira SR, Shin RC, Prado LC, Gavini G, et al. RNA-based assay demonstrated Enterococcus faecalis metabolic activity after chemomechanical procedures. J Endod. 2015;41(9):1441–4.PubMed Pinheiro ET, Candeiro GT, Teixeira SR, Shin RC, Prado LC, Gavini G, et al. RNA-based assay demonstrated Enterococcus faecalis metabolic activity after chemomechanical procedures. J Endod. 2015;41(9):1441–4.PubMed
20.
Zurück zum Zitat de Paz LEC, Bergenholtz G, Svensater G. The effects of antimicrobials on endodontic biofilm bacteria. J Endod. 2010;36(1):70–7. de Paz LEC, Bergenholtz G, Svensater G. The effects of antimicrobials on endodontic biofilm bacteria. J Endod. 2010;36(1):70–7.
21.
Zurück zum Zitat Yang Y, Shen Y, Wang ZJ, Huang XY, Maezono H, Ma JZ, et al. Evaluation of the susceptibility of multispecies biofilms in dentinal tubules to disinfecting solutions. J Endod. 2016;42(8):1246–50.PubMed Yang Y, Shen Y, Wang ZJ, Huang XY, Maezono H, Ma JZ, et al. Evaluation of the susceptibility of multispecies biofilms in dentinal tubules to disinfecting solutions. J Endod. 2016;42(8):1246–50.PubMed
22.
Zurück zum Zitat Liu H, Wei X, Ling J, Wang W, Huang X. Biofilm formation capability of Enterococcus faecalis cells in starvation phase and its susceptibility to sodium hypochlorite. J Endod. 2010;36(4):630–5.PubMed Liu H, Wei X, Ling J, Wang W, Huang X. Biofilm formation capability of Enterococcus faecalis cells in starvation phase and its susceptibility to sodium hypochlorite. J Endod. 2010;36(4):630–5.PubMed
23.
Zurück zum Zitat Du TF, Wang ZJ, Shen Y, Ma JZ, Cao YG, Haapasalo M. Combined antibacterial effect of sodium hypochlorite and root canal sealers against Enterococcus faecalis biofilms in dentin canals. J Endod. 2015;41(8):1294–8.PubMed Du TF, Wang ZJ, Shen Y, Ma JZ, Cao YG, Haapasalo M. Combined antibacterial effect of sodium hypochlorite and root canal sealers against Enterococcus faecalis biofilms in dentin canals. J Endod. 2015;41(8):1294–8.PubMed
24.
Zurück zum Zitat Pladisai P, Ampornaramveth RS, Chivatxaranukul P. Effectiveness of different disinfection protocols on the reduction of bacteria in Enterococcus faecalis biofilm in teeth with large root canals. J Endod. 2016;42(3):460–4.PubMed Pladisai P, Ampornaramveth RS, Chivatxaranukul P. Effectiveness of different disinfection protocols on the reduction of bacteria in Enterococcus faecalis biofilm in teeth with large root canals. J Endod. 2016;42(3):460–4.PubMed
25.
Zurück zum Zitat Rodrigues RCV, Zandi H, Kristoffersen AK, Enersen M, Mdala I, Orstavik D, et al. Influence of the apical preparation size and the irrigant type on bacterial reduction in root canal-treated teeth with apical periodontitis. J Endod. 2017;43(7):1058–63.PubMed Rodrigues RCV, Zandi H, Kristoffersen AK, Enersen M, Mdala I, Orstavik D, et al. Influence of the apical preparation size and the irrigant type on bacterial reduction in root canal-treated teeth with apical periodontitis. J Endod. 2017;43(7):1058–63.PubMed
26.
Zurück zum Zitat Hong SW, Baik JE, Kang SS, Kum KY, Yun CH, Han SH. Sodium hypochlorite inactivates lipoteichoic acid of Enterococcus faecalis by deacylation. J Endod. 2016;42(10):1503–8.PubMed Hong SW, Baik JE, Kang SS, Kum KY, Yun CH, Han SH. Sodium hypochlorite inactivates lipoteichoic acid of Enterococcus faecalis by deacylation. J Endod. 2016;42(10):1503–8.PubMed
27.
Zurück zum Zitat Hand RE, Smith ML, Harrison JW. Analysis of the effect of dilution on the necrotic tissue dissolution property of sodium hypochlorite. J Endod. 1978;4(2):60–4.PubMed Hand RE, Smith ML, Harrison JW. Analysis of the effect of dilution on the necrotic tissue dissolution property of sodium hypochlorite. J Endod. 1978;4(2):60–4.PubMed
28.
Zurück zum Zitat Spangberg L, Engström B, Langeland K. Biologic effects of dental materials: 3. Toxicity and antimicrobial effect of endodontic antiseptics in vitro. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 1973;36(6):856–71. Spangberg L, Engström B, Langeland K. Biologic effects of dental materials: 3. Toxicity and antimicrobial effect of endodontic antiseptics in vitro. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 1973;36(6):856–71.
29.
Zurück zum Zitat Cunningham WT, Balekjian AY. Effect of temperature on collagen-dissolving ability of sodium hypochlorite endodontic irrigant. Oral Surg Oral Med Oral Pathol. 1980;49(2):175–7.PubMed Cunningham WT, Balekjian AY. Effect of temperature on collagen-dissolving ability of sodium hypochlorite endodontic irrigant. Oral Surg Oral Med Oral Pathol. 1980;49(2):175–7.PubMed
30.
Zurück zum Zitat Abou-Rass M, Oglesby SW. The effects of temperature, concentration, and tissue type on the solvent ability of sodium hypochlorite. J Endod. 1981;7(8):376–7.PubMed Abou-Rass M, Oglesby SW. The effects of temperature, concentration, and tissue type on the solvent ability of sodium hypochlorite. J Endod. 1981;7(8):376–7.PubMed
31.
Zurück zum Zitat de Hemptinne F, Slaus G, Vandendael M, Jacquet W, De Moor RJ, Bottenberg P. In vivo intracanal temperature evolution during endodontic treatment after the injection of room temperature or preheated sodium hypochlorite. J Endod. 2015;41(7):1112–5.PubMed de Hemptinne F, Slaus G, Vandendael M, Jacquet W, De Moor RJ, Bottenberg P. In vivo intracanal temperature evolution during endodontic treatment after the injection of room temperature or preheated sodium hypochlorite. J Endod. 2015;41(7):1112–5.PubMed
32.
Zurück zum Zitat Moorer WR, Wesselink PR. Factors promoting the tissue dissolving capability of sodium-hypochlorite. Int Endod J. 1982;15(4):187–96.PubMed Moorer WR, Wesselink PR. Factors promoting the tissue dissolving capability of sodium-hypochlorite. Int Endod J. 1982;15(4):187–96.PubMed
33.
Zurück zum Zitat Stojicic S, Zivkovic S, Qian W, Zhang H, Haapasalo M. Tissue dissolution by sodium hypochlorite: effect of concentration, temperature, agitation, and surfactant. J Endod. 2010;36(9):1558–62.PubMed Stojicic S, Zivkovic S, Qian W, Zhang H, Haapasalo M. Tissue dissolution by sodium hypochlorite: effect of concentration, temperature, agitation, and surfactant. J Endod. 2010;36(9):1558–62.PubMed
34.
Zurück zum Zitat Verma N, Sangwan P, Tewari S, Duhan J. Effect of different concentrations of sodium hypochlorite on outcome of primary root canal treatment: a randomized controlled trial. J Endod. 2019;45(4):357–63.PubMed Verma N, Sangwan P, Tewari S, Duhan J. Effect of different concentrations of sodium hypochlorite on outcome of primary root canal treatment: a randomized controlled trial. J Endod. 2019;45(4):357–63.PubMed
36.
Zurück zum Zitat Wang Z, Shen Y, Haapasalo M. Effectiveness of endodontic disinfecting solutions against young and old Enterococcus faecalis biofilms in dentin canals. J Endod. 2012;38(10):1376–9.PubMed Wang Z, Shen Y, Haapasalo M. Effectiveness of endodontic disinfecting solutions against young and old Enterococcus faecalis biofilms in dentin canals. J Endod. 2012;38(10):1376–9.PubMed
37.
Zurück zum Zitat Zand V, Milani AS, Amini M, Barhaghi MHS, Lotfi M, Rikhtegaran S, et al. Antimicrobial efficacy of photodynamic therapy and sodium hypochlorite on monoculture biofilms of Enterococcus faecalis at different stages of development. Photomed Laser Surg. 2014;32(5):245–51.PubMed Zand V, Milani AS, Amini M, Barhaghi MHS, Lotfi M, Rikhtegaran S, et al. Antimicrobial efficacy of photodynamic therapy and sodium hypochlorite on monoculture biofilms of Enterococcus faecalis at different stages of development. Photomed Laser Surg. 2014;32(5):245–51.PubMed
38.
Zurück zum Zitat Clegg MS, Vertucci FJ, Walker C, Britto LR. The effect of exposure to irrigant solutions on apical dentin biofilms in vitro. J Endod. 2006;32(5):434–7.PubMed Clegg MS, Vertucci FJ, Walker C, Britto LR. The effect of exposure to irrigant solutions on apical dentin biofilms in vitro. J Endod. 2006;32(5):434–7.PubMed
39.
Zurück zum Zitat Moreira DM, Almeida JFA, Ferraz CCR, Gomes BPFD, Line SRP, Zaia AA. Structural analysis of bovine root dentin after use of different endodontics auxiliary chemical substances. J Endod. 2009;35(7):1023–7.PubMed Moreira DM, Almeida JFA, Ferraz CCR, Gomes BPFD, Line SRP, Zaia AA. Structural analysis of bovine root dentin after use of different endodontics auxiliary chemical substances. J Endod. 2009;35(7):1023–7.PubMed
40.
Zurück zum Zitat Nikaido T, Takano Y, Sasafuchi Y, Burrow MF, Tagami J. Bond strengths to endodontically-treated teeth. Am J Dent. 1999;12(4):177–80.PubMed Nikaido T, Takano Y, Sasafuchi Y, Burrow MF, Tagami J. Bond strengths to endodontically-treated teeth. Am J Dent. 1999;12(4):177–80.PubMed
41.
Zurück zum Zitat Guivarc'h M, Ordioni U, Ahmed HMA, Cohen S, Catherine JH, Bukiet F. Sodium hypochlorite accident: a systematic review. J Endod. 2017;43(1):16–24.PubMed Guivarc'h M, Ordioni U, Ahmed HMA, Cohen S, Catherine JH, Bukiet F. Sodium hypochlorite accident: a systematic review. J Endod. 2017;43(1):16–24.PubMed
42.
Zurück zum Zitat Hulsmann M, Hahn W. Complications during root canal irrigation - literature review and case reports. Int Endod J. 2000;33(3):186–93.PubMed Hulsmann M, Hahn W. Complications during root canal irrigation - literature review and case reports. Int Endod J. 2000;33(3):186–93.PubMed
43.
Zurück zum Zitat Spencer HR, Ike V, Brennan PA. Review: the use of sodium hypochlorite in endodontics - potential complications and their management. Br Dent J. 2007;202(9):555–9.PubMed Spencer HR, Ike V, Brennan PA. Review: the use of sodium hypochlorite in endodontics - potential complications and their management. Br Dent J. 2007;202(9):555–9.PubMed
44.
Zurück zum Zitat Basrani B, Haapasalo M. Update on endodontic irrigating solutions. Endodontic Topics. 2012;27(1):74–102. Basrani B, Haapasalo M. Update on endodontic irrigating solutions. Endodontic Topics. 2012;27(1):74–102.
45.
Zurück zum Zitat Zhu WC, Gyamfi J, Niu LN, Schoeffel GJ, Liu SY, Santarcangelo F, et al. Anatomy of sodium hypochlorite accidents involving facial ecchymosis-a review. J Dent. 2013;41(11):935–48.PubMed Zhu WC, Gyamfi J, Niu LN, Schoeffel GJ, Liu SY, Santarcangelo F, et al. Anatomy of sodium hypochlorite accidents involving facial ecchymosis-a review. J Dent. 2013;41(11):935–48.PubMed
46.
Zurück zum Zitat Hales JJ, Jackson CR, Everett AP, Moore SH. Treatment protocol for the management of a sodium hypochlorite accident during endodontic therapy. Gen Dent. 2001;49(3):278–81.PubMed Hales JJ, Jackson CR, Everett AP, Moore SH. Treatment protocol for the management of a sodium hypochlorite accident during endodontic therapy. Gen Dent. 2001;49(3):278–81.PubMed
47.
Zurück zum Zitat Caputa PE, Retsas A, Kuijk L. Chavez de Paz LE, Boutsioukis C. Ultrasonic irrigant activation during root canal treatment: a systematic review. J Endod. 2019;45(1):31–44 e13.PubMed Caputa PE, Retsas A, Kuijk L. Chavez de Paz LE, Boutsioukis C. Ultrasonic irrigant activation during root canal treatment: a systematic review. J Endod. 2019;45(1):31–44 e13.PubMed
48.
Zurück zum Zitat Arias-Moliz MT, Morago A, Ordinola-Zapata R, Ferrer-Luque CM, Ruiz-Linares M, Baca P. Effects of dentin debris on the antimicrobial properties of sodium hypochlorite and etidronic acid. J Endod. 2016;42(5):771–5.PubMed Arias-Moliz MT, Morago A, Ordinola-Zapata R, Ferrer-Luque CM, Ruiz-Linares M, Baca P. Effects of dentin debris on the antimicrobial properties of sodium hypochlorite and etidronic acid. J Endod. 2016;42(5):771–5.PubMed
49.
Zurück zum Zitat Kumar T, Dhillon JS, Gill GS, Singla R, Rani S, Dhillon M. An in vitro comparison of the antimicrobial efficacy of positive pressure and negative pressure irrigation techniques in root canals infected with Enterococcus faecalis. J Conserv Dent. 2018;21(4):438–42.PubMedPubMedCentral Kumar T, Dhillon JS, Gill GS, Singla R, Rani S, Dhillon M. An in vitro comparison of the antimicrobial efficacy of positive pressure and negative pressure irrigation techniques in root canals infected with Enterococcus faecalis. J Conserv Dent. 2018;21(4):438–42.PubMedPubMedCentral
50.
Zurück zum Zitat Hockett JL, Dommisch JK, Johnson JD, Cohenca N. Antimicrobial efficacy of two irrigation techniques in tapered and nontapered canal preparations: an in vitro study. J Endod. 2008;34(11):1374–7.PubMed Hockett JL, Dommisch JK, Johnson JD, Cohenca N. Antimicrobial efficacy of two irrigation techniques in tapered and nontapered canal preparations: an in vitro study. J Endod. 2008;34(11):1374–7.PubMed
51.
Zurück zum Zitat Brito PRR, Souza LC, de Oliveira JCM, Alves FRF, De-Deus G, Lopes HP, et al. Comparison of the effectiveness of three irrigation techniques in reducing intracanal Enterococcus faecalis populations: an in vitro study. J Endod. 2009;35(10):1422–7.PubMed Brito PRR, Souza LC, de Oliveira JCM, Alves FRF, De-Deus G, Lopes HP, et al. Comparison of the effectiveness of three irrigation techniques in reducing intracanal Enterococcus faecalis populations: an in vitro study. J Endod. 2009;35(10):1422–7.PubMed
52.
Zurück zum Zitat Silva EJNL, Carvalho CR, Belladonna FG, Prado MC, Lopes RT, De-Deus G, et al. Micro-CT evaluation of different final irrigation protocols on the removal of hard-tissue debris from isthmus-containing mesial root of mandibular molars. Clin Oral Invest. 2019;23(2):681–7. Silva EJNL, Carvalho CR, Belladonna FG, Prado MC, Lopes RT, De-Deus G, et al. Micro-CT evaluation of different final irrigation protocols on the removal of hard-tissue debris from isthmus-containing mesial root of mandibular molars. Clin Oral Invest. 2019;23(2):681–7.
53.
Zurück zum Zitat Freire LG, Iglecias EF, Cunha RS, Dos Santos M, Gavini G. Micro-computed tomographic evaluation of hard tissue debris removal after different irrigation methods and its influence on the filling of curved canals. J Endod. 2015;41(10):1660–6.PubMed Freire LG, Iglecias EF, Cunha RS, Dos Santos M, Gavini G. Micro-computed tomographic evaluation of hard tissue debris removal after different irrigation methods and its influence on the filling of curved canals. J Endod. 2015;41(10):1660–6.PubMed
54.
Zurück zum Zitat Thomas AR, Velmurugan N, Smita S, Jothilatha S. Comparative evaluation of canal isthmus debridement efficacy of modified EndoVac technique with different irrigation systems. J Endod. 2014;40(10):1676–80.PubMed Thomas AR, Velmurugan N, Smita S, Jothilatha S. Comparative evaluation of canal isthmus debridement efficacy of modified EndoVac technique with different irrigation systems. J Endod. 2014;40(10):1676–80.PubMed
55.
Zurück zum Zitat Azim AA, Aksel H, Zhuang TT, Mashtare T, Babu JP, Huang GTJ. Efficacy of 4 irrigation protocols in killing bacteria colonized in dentinal tubules examined by a novel confocal laser scanning microscope analysis. J Endod. 2016;42(6):928–34.PubMedPubMedCentral Azim AA, Aksel H, Zhuang TT, Mashtare T, Babu JP, Huang GTJ. Efficacy of 4 irrigation protocols in killing bacteria colonized in dentinal tubules examined by a novel confocal laser scanning microscope analysis. J Endod. 2016;42(6):928–34.PubMedPubMedCentral
56.
Zurück zum Zitat Alves FRF, Andrade CV, Marceliano-Alves ME, Perez AR, Rocas IN, Versiani MA, et al. Adjunctive Steps for disinfection of the mandibular molar root canal system: a correlative bacteriologic, micro-computed tomography, and cryopulverization approach. J Endod. 2016;42(11):1667–72.PubMed Alves FRF, Andrade CV, Marceliano-Alves ME, Perez AR, Rocas IN, Versiani MA, et al. Adjunctive Steps for disinfection of the mandibular molar root canal system: a correlative bacteriologic, micro-computed tomography, and cryopulverization approach. J Endod. 2016;42(11):1667–72.PubMed
57.
Zurück zum Zitat Bao PP, Shen Y, Lin J, Haapasalo M. In vitro efficacy of XP-endo finisher with 2 different protocols on biofilm removal from apical root canals. J Endod. 2017;43(2):321–5.PubMed Bao PP, Shen Y, Lin J, Haapasalo M. In vitro efficacy of XP-endo finisher with 2 different protocols on biofilm removal from apical root canals. J Endod. 2017;43(2):321–5.PubMed
58.
Zurück zum Zitat Bedier MM, Hashem AAR, Hassan YM. Improved dentin disinfection by combining different-geometry rotary nickel-titanium files in preparing root canals. Restor Dent Endod. 2018;43(4):e46.PubMedPubMedCentral Bedier MM, Hashem AAR, Hassan YM. Improved dentin disinfection by combining different-geometry rotary nickel-titanium files in preparing root canals. Restor Dent Endod. 2018;43(4):e46.PubMedPubMedCentral
59.
Zurück zum Zitat Xin Y, Yang J, Song KY. In vitro evaluation of the effectiveness of XP-endo Finisher file on smear layer removal after root canal instrumentation. Hua Xi Kou Qiang Yi Xue Za Zhi. 2019;37(1):48–52.PubMed Xin Y, Yang J, Song KY. In vitro evaluation of the effectiveness of XP-endo Finisher file on smear layer removal after root canal instrumentation. Hua Xi Kou Qiang Yi Xue Za Zhi. 2019;37(1):48–52.PubMed
61.
Zurück zum Zitat Zhao Y, Fan W, Xu T, Tay FR, Gutmann JL, Fan B. Evaluation of several instrumentation techniques and irrigation methods on the percentage of untouched canal wall and accumulated dentine debris in C-shaped canals. Int Endod J. . Zhao Y, Fan W, Xu T, Tay FR, Gutmann JL, Fan B. Evaluation of several instrumentation techniques and irrigation methods on the percentage of untouched canal wall and accumulated dentine debris in C-shaped canals. Int Endod J. .
62.
Zurück zum Zitat Haapasalo M, Wang Z, Shen Y, Curtis A, Patel P, Khakpour M. Tissue dissolution by a novel multisonic ultracleaning system and sodium hypochlorite. J Endod. 2014;40(8):1178–81.PubMed Haapasalo M, Wang Z, Shen Y, Curtis A, Patel P, Khakpour M. Tissue dissolution by a novel multisonic ultracleaning system and sodium hypochlorite. J Endod. 2014;40(8):1178–81.PubMed
63.
Zurück zum Zitat Molina B, Glickman G, Vandrangi P, Khakpour M. Evaluation of root canal debridement of human molars using the gentle wave system. J Endod. 2015;41(10):1701–5.PubMed Molina B, Glickman G, Vandrangi P, Khakpour M. Evaluation of root canal debridement of human molars using the gentle wave system. J Endod. 2015;41(10):1701–5.PubMed
64.
Zurück zum Zitat Charara K, Friedman S, Sherman A, Kishen A, Malkhassian G, Khakpour M, et al. Assessment of apical extrusion during root canal irrigation with the novel GentleWave system in a simulated apical environment. J Endod. 2016;42(1):135–9.PubMed Charara K, Friedman S, Sherman A, Kishen A, Malkhassian G, Khakpour M, et al. Assessment of apical extrusion during root canal irrigation with the novel GentleWave system in a simulated apical environment. J Endod. 2016;42(1):135–9.PubMed
65.
Zurück zum Zitat Sigurdsson A, Garland RW, Le KT, Rassoulian SA. Healing of periapical lesions after endodontic treatment with the GentleWave procedure: a prospective multicenter clinical study. J Endod. 2018;44(3):510–7.PubMed Sigurdsson A, Garland RW, Le KT, Rassoulian SA. Healing of periapical lesions after endodontic treatment with the GentleWave procedure: a prospective multicenter clinical study. J Endod. 2018;44(3):510–7.PubMed
66.
Zurück zum Zitat Löe H. Does chlorhexidine have a place in the prophylaxis of dental diseases? LHJPR. 1973;12(Suppl):93–9. Löe H. Does chlorhexidine have a place in the prophylaxis of dental diseases? LHJPR. 1973;12(Suppl):93–9.
67.
Zurück zum Zitat Okino LA, Siqueira EL, Santos M, Bombana AC, Figueiredo JA. Dissolution of pulp tissue by aqueous solution of chlorhexidine digluconate and chlorhexidine digluconate gel. Int Endod J. 2004;37(1):38–41.PubMed Okino LA, Siqueira EL, Santos M, Bombana AC, Figueiredo JA. Dissolution of pulp tissue by aqueous solution of chlorhexidine digluconate and chlorhexidine digluconate gel. Int Endod J. 2004;37(1):38–41.PubMed
68.
Zurück zum Zitat Gomes BP, Vianna ME, Zaia AA, Almeida JF, Souza-Filho FJ, Ferraz CC. Chlorhexidine in endodontics. Braz Dent J. 2013;24(2):89–102.PubMed Gomes BP, Vianna ME, Zaia AA, Almeida JF, Souza-Filho FJ, Ferraz CC. Chlorhexidine in endodontics. Braz Dent J. 2013;24(2):89–102.PubMed
69.
Zurück zum Zitat Bukhary S, Balto H. Antibacterial Efficacy of Octenisept, Alexidine, Chlorhexidine, and sodium hypochlorite against Enterococcus faecalis biofilms. J Endod. 2017;43(4):643–7.PubMed Bukhary S, Balto H. Antibacterial Efficacy of Octenisept, Alexidine, Chlorhexidine, and sodium hypochlorite against Enterococcus faecalis biofilms. J Endod. 2017;43(4):643–7.PubMed
70.
Zurück zum Zitat Spijkervet FK, van Saene JJ, van Saene HK, Panders AK, Vermey A, Fidler V. Chlorhexidine inactivation by saliva. Oral Surg Oral Med Oral Pathol. 1990;69(4):444–9.PubMed Spijkervet FK, van Saene JJ, van Saene HK, Panders AK, Vermey A, Fidler V. Chlorhexidine inactivation by saliva. Oral Surg Oral Med Oral Pathol. 1990;69(4):444–9.PubMed
71.
Zurück zum Zitat Zamany A, Safavi K, Spangberg LSW. The effect of chlorhexidine as an endodontic disinfectant. Oral Surg Oral Med O. 2003;96(5):578–81. Zamany A, Safavi K, Spangberg LSW. The effect of chlorhexidine as an endodontic disinfectant. Oral Surg Oral Med O. 2003;96(5):578–81.
72.
Zurück zum Zitat Sjogren U, Figdor D, Persson S, Sundqvist G. Influence of infection at the time of root filling on the outcome of endodontic treatment of teeth with apical periodontitis. Int Endod J. 1997;30(5):297–306.PubMed Sjogren U, Figdor D, Persson S, Sundqvist G. Influence of infection at the time of root filling on the outcome of endodontic treatment of teeth with apical periodontitis. Int Endod J. 1997;30(5):297–306.PubMed
73.
Zurück zum Zitat Rolla G, Loe H, Schiott CR. The affinity of chlorhexidine for hydroxyapatite and salivary mucins. J Periodontal Res. 1970;5(2):90–5.PubMed Rolla G, Loe H, Schiott CR. The affinity of chlorhexidine for hydroxyapatite and salivary mucins. J Periodontal Res. 1970;5(2):90–5.PubMed
74.
Zurück zum Zitat Rosenthal S, Spångberg L, Safavi K. Chlorhexidine substantivity in root canal dentin. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2004;98(4):488–92.PubMed Rosenthal S, Spångberg L, Safavi K. Chlorhexidine substantivity in root canal dentin. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2004;98(4):488–92.PubMed
75.
Zurück zum Zitat Souza M, Cecchin D, Farina AP, Leite CE, Cruz FF, Pereira Cda C, et al. Evaluation of chlorhexidine substantivity on human dentin: a chemical analysis. J Endod. 2012;38(9):1249–52.PubMed Souza M, Cecchin D, Farina AP, Leite CE, Cruz FF, Pereira Cda C, et al. Evaluation of chlorhexidine substantivity on human dentin: a chemical analysis. J Endod. 2012;38(9):1249–52.PubMed
76.
Zurück zum Zitat Chaves LP, Ciantelli TL, Araujo DFG, Giacomini MC, Tjaderhane L, Scaffa PMC, et al. How proteolytic inhibitors interact with dentin on glass-fiber post luting over 6 months. J Mech Behav Biomed. 2018;79:348–53. Chaves LP, Ciantelli TL, Araujo DFG, Giacomini MC, Tjaderhane L, Scaffa PMC, et al. How proteolytic inhibitors interact with dentin on glass-fiber post luting over 6 months. J Mech Behav Biomed. 2018;79:348–53.
77.
Zurück zum Zitat Basrani BR, Manek S, Sodhi RNS, Fillery E, Manzur A. Interaction between sodium hypochlorite and chlorhexidine gluconate. J Endod. 2007;33(8):966–9.PubMed Basrani BR, Manek S, Sodhi RNS, Fillery E, Manzur A. Interaction between sodium hypochlorite and chlorhexidine gluconate. J Endod. 2007;33(8):966–9.PubMed
78.
Zurück zum Zitat Krishnamurthy S, Sudhakaran S. Evaluation and prevention of the precipitate formed on interaction between sodium hypochlorite and chlorhexidine. J Endod. 2010;36(7):1154–7.PubMed Krishnamurthy S, Sudhakaran S. Evaluation and prevention of the precipitate formed on interaction between sodium hypochlorite and chlorhexidine. J Endod. 2010;36(7):1154–7.PubMed
79.
Zurück zum Zitat Thomas JE, Sem DS. An in vitro spectroscopic analysis to determine whether para-chloroaniline is produced from mixing sodium hypochlorite and chlorhexidine. J Endod. 2010;36(2):315–7.PubMed Thomas JE, Sem DS. An in vitro spectroscopic analysis to determine whether para-chloroaniline is produced from mixing sodium hypochlorite and chlorhexidine. J Endod. 2010;36(2):315–7.PubMed
80.
Zurück zum Zitat Nowicki JB, Sem DS. An in vitro spectroscopic analysis to determine the chemical composition of the precipitate formed by mixing sodium hypochlorite and chlorhexidine. J Endod. 2011;37(7):983–8.PubMedPubMedCentral Nowicki JB, Sem DS. An in vitro spectroscopic analysis to determine the chemical composition of the precipitate formed by mixing sodium hypochlorite and chlorhexidine. J Endod. 2011;37(7):983–8.PubMedPubMedCentral
81.
Zurück zum Zitat Waris G, Ahsan H. Reactive oxygen species: role in the development of cancer and various chronic conditions. Journal of Carcinogenesis. 2006;5(1):14.PubMedPubMedCentral Waris G, Ahsan H. Reactive oxygen species: role in the development of cancer and various chronic conditions. Journal of Carcinogenesis. 2006;5(1):14.PubMedPubMedCentral
82.
Zurück zum Zitat Messmer AS, Nickel CH, Bareiss D. P-chloroaniline poisoning causing methemoglobinemia: a case report and review of the literature. Case Rep Emerg Med. 2015;2015:208732.PubMedPubMedCentral Messmer AS, Nickel CH, Bareiss D. P-chloroaniline poisoning causing methemoglobinemia: a case report and review of the literature. Case Rep Emerg Med. 2015;2015:208732.PubMedPubMedCentral
84.
Zurück zum Zitat Akisue E, Tomita VS, Gavini G, Poli de Figueiredo JA. Effect of the combination of sodium hypochlorite and chlorhexidine on dentinal permeability and scanning electron microscopy precipitate observation. J Endod. 2010;36(5):847–50.PubMed Akisue E, Tomita VS, Gavini G, Poli de Figueiredo JA. Effect of the combination of sodium hypochlorite and chlorhexidine on dentinal permeability and scanning electron microscopy precipitate observation. J Endod. 2010;36(5):847–50.PubMed
85.
Zurück zum Zitat Vivacqua-Gomes N, Ferraz CC, Gomes BP, Zaia AA, Teixeira FB, Souza-Filho FJ. Influence of irrigants on the coronal microleakage of laterally condensed gutta-percha root fillings. Int Endod J. 2002;35(9):791–5.PubMed Vivacqua-Gomes N, Ferraz CC, Gomes BP, Zaia AA, Teixeira FB, Souza-Filho FJ. Influence of irrigants on the coronal microleakage of laterally condensed gutta-percha root fillings. Int Endod J. 2002;35(9):791–5.PubMed
86.
Zurück zum Zitat Prado M, Santos HM, Rezende CM, Pinto AC, Faria RB, Simao RA, et al. Interactions between irrigants commonly used in endodontic practice: a chemical analysis. J Endod. 2013;39(4):505–10.PubMed Prado M, Santos HM, Rezende CM, Pinto AC, Faria RB, Simao RA, et al. Interactions between irrigants commonly used in endodontic practice: a chemical analysis. J Endod. 2013;39(4):505–10.PubMed
87.
Zurück zum Zitat Haapasalo M, Shen Y, Wang Z, Gao Y. Irrigation in endodontics. Br Dent J. 2014;216(6):299–303.PubMed Haapasalo M, Shen Y, Wang Z, Gao Y. Irrigation in endodontics. Br Dent J. 2014;216(6):299–303.PubMed
88.
Zurück zum Zitat de Almeida J, Hoogenkamp M, Felippe WT, Crielaard W, van der Waal SV. Effectiveness of EDTA and modified salt solution to detach and kill cells from Enterococcus faecalis biofilm. J Endod. 2016;42(2):320–3.PubMed de Almeida J, Hoogenkamp M, Felippe WT, Crielaard W, van der Waal SV. Effectiveness of EDTA and modified salt solution to detach and kill cells from Enterococcus faecalis biofilm. J Endod. 2016;42(2):320–3.PubMed
89.
Zurück zum Zitat Herrera DR, Martinho FC, de Jesus-Soares A, Zaia AA, Ferraz CCR, Almeida JFA, et al. Clinical efficacy of EDTA ultrasonic activation in the reduction of endotoxins and cultivable bacteria. Int Endod J. 2017;50(10):933–40.PubMed Herrera DR, Martinho FC, de Jesus-Soares A, Zaia AA, Ferraz CCR, Almeida JFA, et al. Clinical efficacy of EDTA ultrasonic activation in the reduction of endotoxins and cultivable bacteria. Int Endod J. 2017;50(10):933–40.PubMed
90.
Zurück zum Zitat Singla MG, Garg A, Gupta S. MTAD in endodontics: an update review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(3):e70–6.PubMed Singla MG, Garg A, Gupta S. MTAD in endodontics: an update review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(3):e70–6.PubMed
91.
Zurück zum Zitat Jiayi W, Ruijie H. Researchprogress on QMix properties in root canal irrigation. Hua Xi Kou Qiang Yi Xue Za Zhi. 2017;35(5):543–8.PubMed Jiayi W, Ruijie H. Researchprogress on QMix properties in root canal irrigation. Hua Xi Kou Qiang Yi Xue Za Zhi. 2017;35(5):543–8.PubMed
92.
Zurück zum Zitat Shrestha A, Shi Z, Neoh KG, Kishen A. Nanoparticulates for antibiofilm treatment and effect of aging on its antibacterial activity. J Endod. 2010;36(6):1030–5.PubMed Shrestha A, Shi Z, Neoh KG, Kishen A. Nanoparticulates for antibiofilm treatment and effect of aging on its antibacterial activity. J Endod. 2010;36(6):1030–5.PubMed
93.
Zurück zum Zitat Barreras US, Mendez FT, Martinez REM, Valencia CS, Rodriguez PRM, Rodriguez JPL. Chitosan nanoparticles enhance the antibacterial activity of chlorhexidine in collagen membranes used for periapical guided tissue regeneration. Mat Sci Eng C-Mater. 2016;58:1182–7. Barreras US, Mendez FT, Martinez REM, Valencia CS, Rodriguez PRM, Rodriguez JPL. Chitosan nanoparticles enhance the antibacterial activity of chlorhexidine in collagen membranes used for periapical guided tissue regeneration. Mat Sci Eng C-Mater. 2016;58:1182–7.
94.
Zurück zum Zitat Li FC, Kishen A. Microtissue engineering root canal dentine with crosslinked biopolymeric nanoparticles for mechanical stabilization. Int Endod J. 2018;51(10):1171–80.PubMed Li FC, Kishen A. Microtissue engineering root canal dentine with crosslinked biopolymeric nanoparticles for mechanical stabilization. Int Endod J. 2018;51(10):1171–80.PubMed
95.
Zurück zum Zitat Hashmi A, Zhang X, Kishen A. Impact of dentin substrate modification with chitosan-hydroxyapatite precursor nanocomplexes on sealer penetration and tensile strength. J Endod. 2019. Hashmi A, Zhang X, Kishen A. Impact of dentin substrate modification with chitosan-hydroxyapatite precursor nanocomplexes on sealer penetration and tensile strength. J Endod. 2019.
96.
Zurück zum Zitat Rodrigues CT, de Andrade FB, de Vasconcelos LRSM, Midena RZ, Pereira TC, Kuga MC, et al. Antibacterial properties of silver nanoparticles as a root canal irrigant against Enterococcus faecalis biofilm and infected dentinal tubules. Int Endod J. 2018;51(8):901–11.PubMed Rodrigues CT, de Andrade FB, de Vasconcelos LRSM, Midena RZ, Pereira TC, Kuga MC, et al. Antibacterial properties of silver nanoparticles as a root canal irrigant against Enterococcus faecalis biofilm and infected dentinal tubules. Int Endod J. 2018;51(8):901–11.PubMed
97.
Zurück zum Zitat Wu DM, Fan W, Kishen A, Gutmann JL, Fan B. Evaluation of the antibacterial efficacy of silver nanoparticles against Enterococcus faecalis biofilm. J Endod. 2014;40(2):285–90.PubMed Wu DM, Fan W, Kishen A, Gutmann JL, Fan B. Evaluation of the antibacterial efficacy of silver nanoparticles against Enterococcus faecalis biofilm. J Endod. 2014;40(2):285–90.PubMed
98.
Zurück zum Zitat Shrestha A, Kishen A. Antibacterial nanoparticles in endodontics: a review. J Endod. 2016;42(10):1417–26.PubMed Shrestha A, Kishen A. Antibacterial nanoparticles in endodontics: a review. J Endod. 2016;42(10):1417–26.PubMed
99.
Zurück zum Zitat Gomes JE, Silva FO, Watanabe S, Cintra LTA, Tendoro KV, Dalto LG, et al. Tissue reaction to silver nanoparticles dispersion as an alternative irrigating solution. J Endod. 2010;36(10):1698–702. Gomes JE, Silva FO, Watanabe S, Cintra LTA, Tendoro KV, Dalto LG, et al. Tissue reaction to silver nanoparticles dispersion as an alternative irrigating solution. J Endod. 2010;36(10):1698–702.
100.
Zurück zum Zitat Bukhari S, Kim D, Liu Y, Karabucak B, Koo H. Novel endodontic disinfection approach using catalytic nanoparticles. J Endod. 2018;44(5):806–12.PubMedPubMedCentral Bukhari S, Kim D, Liu Y, Karabucak B, Koo H. Novel endodontic disinfection approach using catalytic nanoparticles. J Endod. 2018;44(5):806–12.PubMedPubMedCentral
101.
Zurück zum Zitat Hwang G, Paula AJ, Hunter EE, Liu Y, Babeer A, Karabucak B, et al. Catalytic antimicrobial robots for biofilm eradication. Sci Robot. 2019;4:eaaw2388.PubMedPubMedCentral Hwang G, Paula AJ, Hunter EE, Liu Y, Babeer A, Karabucak B, et al. Catalytic antimicrobial robots for biofilm eradication. Sci Robot. 2019;4:eaaw2388.PubMedPubMedCentral
102.
Zurück zum Zitat Hamblin MR, Hasan T. Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem Photobiol Sci. 2004;3(5):436–50.PubMedPubMedCentral Hamblin MR, Hasan T. Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem Photobiol Sci. 2004;3(5):436–50.PubMedPubMedCentral
103.
Zurück zum Zitat Rodig T, Endres S, Konietschke F, Zimmermann O, Sydow HG, Wiegand A. Effect of fiber insertion depth on antibacterial efficacy of photodynamic therapy against Enterococcus faecalis in rootcanals. Clin Oral Investig. 2017;21(5):1753–9.PubMed Rodig T, Endres S, Konietschke F, Zimmermann O, Sydow HG, Wiegand A. Effect of fiber insertion depth on antibacterial efficacy of photodynamic therapy against Enterococcus faecalis in rootcanals. Clin Oral Investig. 2017;21(5):1753–9.PubMed
104.
Zurück zum Zitat Asnaashari M, Mojahedi SM, Asadi Z, Azari-Marhabi S, Maleki A. A comparison of the antibacterial activity of the two methods of photodynamic therapy (using diode laser 810 nm and LED lamp 630 nm) against Enterococcus faecalis in extracted human anterior teeth. Photodiagn Photodyn. 2016;13:233–7. Asnaashari M, Mojahedi SM, Asadi Z, Azari-Marhabi S, Maleki A. A comparison of the antibacterial activity of the two methods of photodynamic therapy (using diode laser 810 nm and LED lamp 630 nm) against Enterococcus faecalis in extracted human anterior teeth. Photodiagn Photodyn. 2016;13:233–7.
105.
Zurück zum Zitat Garcez AS, Nunez SC, Hamblin MR, Ribeiro MS. Antimicrobial effects of photodynamic therapy on patients with necrotic pulps and periapical lesion. J Endod. 2008;34(2):138–42.PubMed Garcez AS, Nunez SC, Hamblin MR, Ribeiro MS. Antimicrobial effects of photodynamic therapy on patients with necrotic pulps and periapical lesion. J Endod. 2008;34(2):138–42.PubMed
106.
Zurück zum Zitat Garcez AS, Nunez SC, Hamblim MR, Suzuki H, Ribeiro MS. Photodynamic therapy associated with conventional endodontic treatment in patients with antibiotic-resistant microflora: a preliminary report. J Endod. 2010;36(9):1463–6.PubMed Garcez AS, Nunez SC, Hamblim MR, Suzuki H, Ribeiro MS. Photodynamic therapy associated with conventional endodontic treatment in patients with antibiotic-resistant microflora: a preliminary report. J Endod. 2010;36(9):1463–6.PubMed
107.
Zurück zum Zitat Muhammad OH, Engineer MCR, Rocca JP, Brulat-Bouchard N, Medioni E. Photodynamic therapy versus ultrasonic irrigation: interaction with endodontic microbial biofilm, an ex vivo study. Photodiagn Photodyn. 2014;11(2):171–81. Muhammad OH, Engineer MCR, Rocca JP, Brulat-Bouchard N, Medioni E. Photodynamic therapy versus ultrasonic irrigation: interaction with endodontic microbial biofilm, an ex vivo study. Photodiagn Photodyn. 2014;11(2):171–81.
108.
Zurück zum Zitat Zehnder M. Root canal irrigants. J Endod. 2006;32(5):389–98.PubMed Zehnder M. Root canal irrigants. J Endod. 2006;32(5):389–98.PubMed
109.
Zurück zum Zitat Wang ZJ, Maezono H, Shen Y, Haapasalo M. Evaluation of root canal dentin erosion after different irrigation methods using energy-dispersive X-ray spectroscopy. J Endod. 2016;42(12):1834–9.PubMed Wang ZJ, Maezono H, Shen Y, Haapasalo M. Evaluation of root canal dentin erosion after different irrigation methods using energy-dispersive X-ray spectroscopy. J Endod. 2016;42(12):1834–9.PubMed
110.
Zurück zum Zitat Rossi-Fedele G, Dogramaci EJ, Guastalli AR, Steier L, de Figueiredo JAP. Antagonistic interactions between sodium hypochlorite, chlorhexidine, EDTA, and citric acid. J Endod. 2012;38(4):426–31.PubMed Rossi-Fedele G, Dogramaci EJ, Guastalli AR, Steier L, de Figueiredo JAP. Antagonistic interactions between sodium hypochlorite, chlorhexidine, EDTA, and citric acid. J Endod. 2012;38(4):426–31.PubMed
Metadaten
Titel
Irrigation in Endodontics: a Review
verfasst von
Sarah Bukhari
Alaa Babaeer
Publikationsdatum
08.12.2019
Verlag
Springer International Publishing
Erschienen in
Current Oral Health Reports / Ausgabe 4/2019
Elektronische ISSN: 2196-3002
DOI
https://doi.org/10.1007/s40496-019-00241-6

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