Skip to main content
Erschienen in: Breast Cancer Research and Treatment 2/2019

05.06.2019 | Epidemiology

Is core needle biopsy effective at diagnosing male breast lesions?

verfasst von: Yinlong Yang, Shiping Li, Guangyu Liu, Zhiming Shao

Erschienen in: Breast Cancer Research and Treatment | Ausgabe 2/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The objective of this study was to examine the diagnostic accuracy of sonographically guided core needle biopsy (CNB) of breast lesions in men.

Methods

This was a retrospective study where we analyzed consecutive sonographically guided 14-gauge CNB results on 234 male breast lesions. The CNB accuracy is determined by the comparison between the CNB and its corresponding excisional biopsy or to long-term follow-up imaging.

Results

Sonographically guided CNB was effective to collect satisfactory samples from all 234 lesions. Out of those, 58.55% (137/234) were benign, 38.0% (89/234) were malignant, 1.71% (4/234) were papilloma with atypia and 1.71% (4/234) were atypical ductal hyperplasia lesions. Underestimation occurred in 3.4% (8/234) of the lesions. As for the detection of breast malignancy, the sensitivity of the CNB is 98.9%, specificity is 100%, negative predictive value is 99.3%, positive predictive value is 100%, false positive is 0% and false negative is 1.1%. The overall accuracy of sonographically guided CNB as a diagnostic tool is 99.6%.

Conclusion

Sonographically guided 14-gauge CNB is an accurate, reliable and low invasive procedure for assessing breast lesions in men. Triple tests and follow-up checks of benign cases are essential for a successful breast biopsy program in men.
Literatur
4.
Zurück zum Zitat Meattini I, Bicchierai G, Saieva C, De Benedetto D, Desideri I, Becherini C, Abdulcadir D, Vanzi E, Boeri C, Gabbrielli S, Lucci F, Sanchez L, Casella D, Bernini M, Orzalesi L, Vezzosi V, Greto D, Mangoni M, Bianchi S, Livi L, Nori J (2017) Impact of molecular subtypes classification concordance between preoperative core needle biopsy and surgical specimen on early breast cancer management: single-institution experience and review of published literature. Eur J Surg Oncol 43(4):642–648. https://doi.org/10.1016/j.ejso.2016.10.025 CrossRefPubMed Meattini I, Bicchierai G, Saieva C, De Benedetto D, Desideri I, Becherini C, Abdulcadir D, Vanzi E, Boeri C, Gabbrielli S, Lucci F, Sanchez L, Casella D, Bernini M, Orzalesi L, Vezzosi V, Greto D, Mangoni M, Bianchi S, Livi L, Nori J (2017) Impact of molecular subtypes classification concordance between preoperative core needle biopsy and surgical specimen on early breast cancer management: single-institution experience and review of published literature. Eur J Surg Oncol 43(4):642–648. https://​doi.​org/​10.​1016/​j.​ejso.​2016.​10.​025 CrossRefPubMed
10.
Zurück zum Zitat Bazzocchi M, Vianello E, Linda A, Londero V, Zuiani C (2010) Male breast lesions: which abnormalities really need core needle biopsy? Tumori 96(2):266–270CrossRefPubMed Bazzocchi M, Vianello E, Linda A, Londero V, Zuiani C (2010) Male breast lesions: which abnormalities really need core needle biopsy? Tumori 96(2):266–270CrossRefPubMed
14.
Metadaten
Titel
Is core needle biopsy effective at diagnosing male breast lesions?
verfasst von
Yinlong Yang
Shiping Li
Guangyu Liu
Zhiming Shao
Publikationsdatum
05.06.2019
Verlag
Springer US
Erschienen in
Breast Cancer Research and Treatment / Ausgabe 2/2019
Print ISSN: 0167-6806
Elektronische ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-019-05312-x

Weitere Artikel der Ausgabe 2/2019

Breast Cancer Research and Treatment 2/2019 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.