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Erschienen in: European Archives of Psychiatry and Clinical Neuroscience 7/2018

21.06.2017 | Original Paper

Is electroconvulsive therapy an evidence-based treatment for catatonia? A systematic review and meta-analysis

verfasst von: Arnaud Leroy, Florian Naudet, Guillaume Vaiva, Andrew Francis, Pierre Thomas, Ali Amad

Erschienen in: European Archives of Psychiatry and Clinical Neuroscience | Ausgabe 7/2018

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Abstract

We aimed to review and discuss the evidence-based arguments for the efficacy of electroconvulsive therapy (ECT) in the treatment of catatonia. Randomized controlled trials (RCTs) and observational studies focusing on the response to ECT in catatonia were selected in PubMed, the Cochrane Library, Embase, ClinicalTrials.gov and Current Controlled Trials through October 2016 and qualitatively described. Trials assessing pre-post differences using a catatonia or clinical improvement rating scale were pooled together using a random effect model. Secondary outcomes were adverse effects of anesthesia and seizure. 564 patients from 28 studies were included. RCTs were of low quality and were heterogeneous; therefore, it was not possible to combine their efficacy results. An improvement of catatonic symptoms after ECT treatment was evidenced in ten studies (SMD = −3.14, 95% CI [−3.95; −2.34]). The adverse effects that were reported in seven studies included mental confusion, memory loss, headache, or adverse effects associated with anesthesia. ECT protocols were heterogeneous. The literature consistently describes improvement in catatonic symptoms after ECT. However, the published studies fail to demonstrate efficacy and effectiveness. It is now crucial to design and perform a quality RCT to robustly validate the use of ECT in catatonia.
Prospero registration information: PROSPERO 2016: CRD42016041660
Literatur
5.
Zurück zum Zitat Hawkins JM, Archer KJ, Strakowski SM, Keck PE (1995) Somatic treatment of catatonia. Int J Psychiatry Med 25:345–369CrossRefPubMed Hawkins JM, Archer KJ, Strakowski SM, Keck PE (1995) Somatic treatment of catatonia. Int J Psychiatry Med 25:345–369CrossRefPubMed
7.
Zurück zum Zitat NICE (2003) Guidance on the use of electroconvulsive therapy NICE (2003) Guidance on the use of electroconvulsive therapy
9.
Zurück zum Zitat Phutane VH, Thirthalli J, Muralidharan K et al (2013) Double-blind randomized controlled study showing symptomatic and cognitive superiority of bifrontal over bitemporal electrode placement during electroconvulsive therapy for schizophrenia. Brain Stimul 6:210–217. doi:10.1016/j.brs.2012.04.002 CrossRefPubMed Phutane VH, Thirthalli J, Muralidharan K et al (2013) Double-blind randomized controlled study showing symptomatic and cognitive superiority of bifrontal over bitemporal electrode placement during electroconvulsive therapy for schizophrenia. Brain Stimul 6:210–217. doi:10.​1016/​j.​brs.​2012.​04.​002 CrossRefPubMed
11.
Zurück zum Zitat Flamarique I, Baeza I, de la Serna E et al (2015) Long-term effectiveness of electroconvulsive therapy in adolescents with schizophrenia spectrum disorders. Eur Child Adolesc Psychiatry 24:517–524. doi:10.1007/s00787-014-0602-3 CrossRefPubMed Flamarique I, Baeza I, de la Serna E et al (2015) Long-term effectiveness of electroconvulsive therapy in adolescents with schizophrenia spectrum disorders. Eur Child Adolesc Psychiatry 24:517–524. doi:10.​1007/​s00787-014-0602-3 CrossRefPubMed
12.
Zurück zum Zitat Suzuki K, Awata S, Matsuoka H (2004) One-year outcome after response to ECT in middle-aged and elderly patients with intractable catatonic schizophrenia. J ECT 20:99–106CrossRefPubMed Suzuki K, Awata S, Matsuoka H (2004) One-year outcome after response to ECT in middle-aged and elderly patients with intractable catatonic schizophrenia. J ECT 20:99–106CrossRefPubMed
13.
Zurück zum Zitat Girish K, Gill NS (2003) Electroconvulsive therapy in lorazepam non-responsive catatonia. Indian J Psychiatry 45:21–25PubMedPubMedCentral Girish K, Gill NS (2003) Electroconvulsive therapy in lorazepam non-responsive catatonia. Indian J Psychiatry 45:21–25PubMedPubMedCentral
14.
Zurück zum Zitat Miller DH, Clancy J, Cumming E (1953) A comparison between unidirectional current nonconvulsive electrical stimulation given with Reiter’s machine, standard alternating current electro-shock (Cerletti method), and pentothal in chronic schizophrenia. Am J Psychiatry 109:617–620. doi:10.1176/ajp.109.8.617 CrossRefPubMed Miller DH, Clancy J, Cumming E (1953) A comparison between unidirectional current nonconvulsive electrical stimulation given with Reiter’s machine, standard alternating current electro-shock (Cerletti method), and pentothal in chronic schizophrenia. Am J Psychiatry 109:617–620. doi:10.​1176/​ajp.​109.​8.​617 CrossRefPubMed
15.
16.
Zurück zum Zitat Abrams R, Taylor MA (1976) Catatonia. A prospective clinical study. Arch Gen Psychiatry 33:579–581CrossRefPubMed Abrams R, Taylor MA (1976) Catatonia. A prospective clinical study. Arch Gen Psychiatry 33:579–581CrossRefPubMed
21.
Zurück zum Zitat Pataki J, Zervas IM, Jandorf L (1992) Catatonia in a University Inpatient Service (1985–1990). Convuls Ther 8:163–173PubMed Pataki J, Zervas IM, Jandorf L (1992) Catatonia in a University Inpatient Service (1985–1990). Convuls Ther 8:163–173PubMed
22.
Zurück zum Zitat Santos AD, Oliveira MC, Andrade TDS et al (2013) Twenty years of electroconvulsive therapy in a psychiatric unit at a university general hospital. Trends Psychiatry Psychother 35:229–233CrossRefPubMed Santos AD, Oliveira MC, Andrade TDS et al (2013) Twenty years of electroconvulsive therapy in a psychiatric unit at a university general hospital. Trends Psychiatry Psychother 35:229–233CrossRefPubMed
23.
Zurück zum Zitat Taylor MA, Abrams R (1977) Catatonia. Prevalence and importance in the manic phase of manic-depressive illness. Arch Gen Psychiatry 34:1223–1225CrossRefPubMed Taylor MA, Abrams R (1977) Catatonia. Prevalence and importance in the manic phase of manic-depressive illness. Arch Gen Psychiatry 34:1223–1225CrossRefPubMed
24.
Zurück zum Zitat Medda P, Toni C, Luchini F et al (2015) Catatonia in 26 patients with bipolar disorder: clinical features and response to electroconvulsive therapy. Bipolar Disord 17:892–901. doi:10.1111/bdi.12348 CrossRefPubMed Medda P, Toni C, Luchini F et al (2015) Catatonia in 26 patients with bipolar disorder: clinical features and response to electroconvulsive therapy. Bipolar Disord 17:892–901. doi:10.​1111/​bdi.​12348 CrossRefPubMed
25.
Zurück zum Zitat Escobar R, Rios A, Montoya ID et al (2000) Clinical and cerebral blood flow changes in catatonic patients treated with ECT. J Psychosom Res 49:423–429CrossRefPubMed Escobar R, Rios A, Montoya ID et al (2000) Clinical and cerebral blood flow changes in catatonic patients treated with ECT. J Psychosom Res 49:423–429CrossRefPubMed
27.
Zurück zum Zitat Rohland BM, Carroll BT, Jacoby RG (1993) ECT in the treatment of the catatonic syndrome. J Affect Disord 29:255–261CrossRefPubMed Rohland BM, Carroll BT, Jacoby RG (1993) ECT in the treatment of the catatonic syndrome. J Affect Disord 29:255–261CrossRefPubMed
31.
Zurück zum Zitat Bush G, Fink M, Petrides G et al (1996) Catatonia. II. Treatment with lorazepam and electroconvulsive therapy. Acta Psychiatr Scand 93:137–143CrossRefPubMed Bush G, Fink M, Petrides G et al (1996) Catatonia. II. Treatment with lorazepam and electroconvulsive therapy. Acta Psychiatr Scand 93:137–143CrossRefPubMed
33.
Zurück zum Zitat Benzoni O, Fazzari G, Manragoni C et al (2015) Treatment of resistant mood and schizoaffective disorders with electroconvulsive therapy: a case series of 264 patients. J Psychopathol 21:266–268 Benzoni O, Fazzari G, Manragoni C et al (2015) Treatment of resistant mood and schizoaffective disorders with electroconvulsive therapy: a case series of 264 patients. J Psychopathol 21:266–268
35.
Zurück zum Zitat Payee H, Chandrasekaran R, Raju GV (1999) Catatonic syndrome: treatment response to lorazepam. Indian J Psychiatry 41:49–53PubMedPubMedCentral Payee H, Chandrasekaran R, Raju GV (1999) Catatonic syndrome: treatment response to lorazepam. Indian J Psychiatry 41:49–53PubMedPubMedCentral
39.
Zurück zum Zitat Maletzky BM (2004) The first-line use of electroconvulsive therapy in major affective disorders. J ECT 20:112–117CrossRefPubMed Maletzky BM (2004) The first-line use of electroconvulsive therapy in major affective disorders. J ECT 20:112–117CrossRefPubMed
42.
49.
Zurück zum Zitat Glass RM (2001) Electroconvulsive therapy: time to bring it out of the shadows. JAMA 285:1346–1348CrossRefPubMed Glass RM (2001) Electroconvulsive therapy: time to bring it out of the shadows. JAMA 285:1346–1348CrossRefPubMed
50.
Zurück zum Zitat Fink M (2001) Convulsive therapy: a review of the first 55 years. J Affect Disord 63:1–15CrossRefPubMed Fink M (2001) Convulsive therapy: a review of the first 55 years. J Affect Disord 63:1–15CrossRefPubMed
51.
Zurück zum Zitat Dowman J, Patel A, Rajput K (2005) Electroconvulsive therapy: attitudes and misconceptions. J ECT 21:84–87CrossRefPubMed Dowman J, Patel A, Rajput K (2005) Electroconvulsive therapy: attitudes and misconceptions. J ECT 21:84–87CrossRefPubMed
Metadaten
Titel
Is electroconvulsive therapy an evidence-based treatment for catatonia? A systematic review and meta-analysis
verfasst von
Arnaud Leroy
Florian Naudet
Guillaume Vaiva
Andrew Francis
Pierre Thomas
Ali Amad
Publikationsdatum
21.06.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
European Archives of Psychiatry and Clinical Neuroscience / Ausgabe 7/2018
Print ISSN: 0940-1334
Elektronische ISSN: 1433-8491
DOI
https://doi.org/10.1007/s00406-017-0819-5

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