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Erschienen in: Surgical Endoscopy 9/2019

19.11.2018 | 2018 EAES Oral

Is laparoscopic left adrenalectomy with the anterior submesocolic approach for Conn’s or Cushing’s syndrome equally safe and effective as the lateral and anterior ones?

verfasst von: Andrea Balla, Silvia Quaresima, Livia Palmieri, Monica Ortenzi, Emilia Sbardella, Giulia Puliani, Andrea M. Isidori, Mario Guerrieri, Alessandro M. Paganini

Erschienen in: Surgical Endoscopy | Ausgabe 9/2019

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Abstract

Background

The aim of the present study is to report and to compare the results of three different laparoscopic transperitoneal surgical approaches [lateral transperitoneal (LT), anterior transperitoneal (AT) and anterior transperitoneal submesocolic (ATS)] for the treatment of Conn’s and Cushing’s syndrome from left adrenal disease.

Methods

This study is a retrospective analysis of prospectively collected data. From 1994 to 2017, 535 laparoscopic adrenalectomies (LA) were performed. One hundred and sixty-four patients with Conn’s or Cushing’s syndrome underwent left LA. Patients were divided in three groups based on the approach: LT (Group A), AT (Group B) and ATS (Group C).

Results

The diagnosis was Conn’s and Cushing’s syndrome in 99 and 65 patients, respectively. LT was used in 13 cases, AT in 55 and ATS in 96. No significant differences in patient’s gender, age and BMI were observed. Mean operative time was 117.6 ± 33.7, 107.6 ± 40.3 and 96.2 ± 47.5 min for Groups A, B and C, respectively. Conversion to open surgery was observed in 4 Group C patients (4.1%). Morbidity occurred in 2 Group B (2%) and in 5 Group C patients (5.2%).

Conclusions

In case of Conn’s or Cushing’s syndrome, left LA with ATS approach is equally safe and effective as compared to the LT and AT approaches. Early control of the adrenal vein with minimal gland manipulation and limited surgical dissection are the major advantages of the submesocolic approach. Even if statistically significant differences are not observed, postoperative results are the same as those reported in the literature with other approaches.
Literatur
2.
Zurück zum Zitat Hazzan D, Shiloni E, Golijanin D, Jurim O, Gross D, Reissman P (2001) Laparoscopic vs open adrenalectomy for benign adrenal neoplasm. Surg Endosc 15(11):1356–1358CrossRefPubMed Hazzan D, Shiloni E, Golijanin D, Jurim O, Gross D, Reissman P (2001) Laparoscopic vs open adrenalectomy for benign adrenal neoplasm. Surg Endosc 15(11):1356–1358CrossRefPubMed
4.
Zurück zum Zitat Marek-Safiejko M, Safiejko K, Łukaszewicz J, Dadan J, Ładny RJ, Kozłowski R, Wojskowicz P, Myśliwiec P (2016) A comparison of two approaches to laparoscopic adrenalectomy: lateral transperitoneal versus posterior retroperitoneal approach. Adv Clin Exp Med 25(5):829–835. https://doi.org/10.17219/acem/62347 CrossRefPubMed Marek-Safiejko M, Safiejko K, Łukaszewicz J, Dadan J, Ładny RJ, Kozłowski R, Wojskowicz P, Myśliwiec P (2016) A comparison of two approaches to laparoscopic adrenalectomy: lateral transperitoneal versus posterior retroperitoneal approach. Adv Clin Exp Med 25(5):829–835. https://​doi.​org/​10.​17219/​acem/​62347 CrossRefPubMed
6.
Zurück zum Zitat Scoglio D, Balla A, Paci M, Guerrieri M, Lezoche G, D’Ambrosio G, Fabiani B, Ursi P, Paganini AM (2013) Laparoscopic transperitoneal anterior adrenalectomy. Ann Ital Chir 84(4):411–416PubMed Scoglio D, Balla A, Paci M, Guerrieri M, Lezoche G, D’Ambrosio G, Fabiani B, Ursi P, Paganini AM (2013) Laparoscopic transperitoneal anterior adrenalectomy. Ann Ital Chir 84(4):411–416PubMed
9.
Zurück zum Zitat Wittayapairoch J, Jenwitheesuk K, Punchai S, Saeseow OT, Thanapaisal C, Paonariang K (2015) Laparoscopic adrenalectomy: 6 years experience in Srinagarind Hospital. J Med Assoc Thai 98(Suppl 7):S174–S178PubMed Wittayapairoch J, Jenwitheesuk K, Punchai S, Saeseow OT, Thanapaisal C, Paonariang K (2015) Laparoscopic adrenalectomy: 6 years experience in Srinagarind Hospital. J Med Assoc Thai 98(Suppl 7):S174–S178PubMed
13.
Zurück zum Zitat Vorselaars WMCM, Postma EL, Mirallie E, Thiery J, Lustgarten M, Pasternak JD, Bellantone R, Raffaelli M, Fahey T, Vriens MR, Bresler L, Brunaud L, Zarnegar R (2017) Hemodynamic instability during surgery for pheochromocytoma: comparing the transperitoneal and retroperitoneal approach in a multicenter analysis of 341 patients. Surgery. https://doi.org/10.1016/j.surg.2017.05.029 CrossRefPubMed Vorselaars WMCM, Postma EL, Mirallie E, Thiery J, Lustgarten M, Pasternak JD, Bellantone R, Raffaelli M, Fahey T, Vriens MR, Bresler L, Brunaud L, Zarnegar R (2017) Hemodynamic instability during surgery for pheochromocytoma: comparing the transperitoneal and retroperitoneal approach in a multicenter analysis of 341 patients. Surgery. https://​doi.​org/​10.​1016/​j.​surg.​2017.​05.​029 CrossRefPubMed
15.
Zurück zum Zitat Fassnacht M, Arlt W, Bancos I, Dralle H, Newell-Price J, Sahdev A, Tabarin A, Terzolo M, Tsagarakis S, Dekkers OM (2016) Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. Eur J Endocrinol 175(2):G1–G34. https://doi.org/10.1530/EJE-16-0467 CrossRefPubMed Fassnacht M, Arlt W, Bancos I, Dralle H, Newell-Price J, Sahdev A, Tabarin A, Terzolo M, Tsagarakis S, Dekkers OM (2016) Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. Eur J Endocrinol 175(2):G1–G34. https://​doi.​org/​10.​1530/​EJE-16-0467 CrossRefPubMed
16.
Zurück zum Zitat Funder JW, Carey RM, Mantero F, Murad MH, Reincke M, Shibata H, Stowasser M, Young WF Jr (2016) The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 101(5):1889–1916. https://doi.org/10.1210/jc.2015-4061 CrossRefPubMed Funder JW, Carey RM, Mantero F, Murad MH, Reincke M, Shibata H, Stowasser M, Young WF Jr (2016) The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 101(5):1889–1916. https://​doi.​org/​10.​1210/​jc.​2015-4061 CrossRefPubMed
17.
Zurück zum Zitat Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M, Young WF Jr, Montori VM, Endocrine Society (2008) Case detection, diagnosis, and treatment of patients with primary aldosteronism: an Endocrinesociety Clinical Practice Guideline. J Clin Endocrinol Metab 93(9):3266–3281. https://doi.org/10.1210/jc.2008-0104 CrossRefPubMed Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M, Young WF Jr, Montori VM, Endocrine Society (2008) Case detection, diagnosis, and treatment of patients with primary aldosteronism: an Endocrinesociety Clinical Practice Guideline. J Clin Endocrinol Metab 93(9):3266–3281. https://​doi.​org/​10.​1210/​jc.​2008-0104 CrossRefPubMed
18.
Zurück zum Zitat Daunt N (2005) Adrenal vein sampling: how to make it quick, easy, and successful. Radiographics 25(Suppl 1):S143–S158CrossRefPubMed Daunt N (2005) Adrenal vein sampling: how to make it quick, easy, and successful. Radiographics 25(Suppl 1):S143–S158CrossRefPubMed
20.
Zurück zum Zitat Paragliola RM, Ricciato MP, Gallo F, De Rosa A, Ianni F, Locantore P, Senes P, Pontecorvi A, Corsello SM (2010) Preoperative and postoperative management of adrenal masses. G Chir 31(6–7):332–335PubMed Paragliola RM, Ricciato MP, Gallo F, De Rosa A, Ianni F, Locantore P, Senes P, Pontecorvi A, Corsello SM (2010) Preoperative and postoperative management of adrenal masses. G Chir 31(6–7):332–335PubMed
22.
Zurück zum Zitat Lezoche E, Guerrieri M, Feliciotti F, Paganini AM, Perretta S, Baldarelli M, Bonjer J, Miccoli P (2002) Anterior, lateral, and posterior retroperitoneal approaches in endoscopic adrenalectomy. Surg Endosc 16(1):96–99CrossRefPubMed Lezoche E, Guerrieri M, Feliciotti F, Paganini AM, Perretta S, Baldarelli M, Bonjer J, Miccoli P (2002) Anterior, lateral, and posterior retroperitoneal approaches in endoscopic adrenalectomy. Surg Endosc 16(1):96–99CrossRefPubMed
23.
Zurück zum Zitat Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibañes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M (2009) The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187–196CrossRefPubMed Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, de Santibañes E, Pekolj J, Slankamenac K, Bassi C, Graf R, Vonlanthen R, Padbury R, Cameron JL, Makuuchi M (2009) The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187–196CrossRefPubMed
25.
Zurück zum Zitat Gagner M, Pomp A, Heniford BT, Pharand D, Lacroix A (1997) Laparoscopic adrenalectomy: lessons learned from 100 consecutive procedures. Ann Surg 226(3):238–246; discussion 246–247CrossRefPubMedPubMedCentral Gagner M, Pomp A, Heniford BT, Pharand D, Lacroix A (1997) Laparoscopic adrenalectomy: lessons learned from 100 consecutive procedures. Ann Surg 226(3):238–246; discussion 246–247CrossRefPubMedPubMedCentral
26.
Zurück zum Zitat Gumbs AA, Gagner M (2006) Laparoscopic adrenalectomy. Best Pract Res Clin Endocrinol Metab 20(3):483–499CrossRefPubMed Gumbs AA, Gagner M (2006) Laparoscopic adrenalectomy. Best Pract Res Clin Endocrinol Metab 20(3):483–499CrossRefPubMed
27.
Zurück zum Zitat Tanaka M, Tokuda N, Koga H, Kimoto Y, Naito S (2000) Laparoscopic adrenalectomy for pheochromocytoma: comparison with open adrenalectomy and comparison of laparoscopic surgery for pheochromocytoma versus other adrenal tumors. J Endourol 14(5):427–431CrossRefPubMed Tanaka M, Tokuda N, Koga H, Kimoto Y, Naito S (2000) Laparoscopic adrenalectomy for pheochromocytoma: comparison with open adrenalectomy and comparison of laparoscopic surgery for pheochromocytoma versus other adrenal tumors. J Endourol 14(5):427–431CrossRefPubMed
28.
Zurück zum Zitat Davies MJ, McGlade DP, Banting SW (2004) A comparison of open and laparoscopic approaches to adrenalectomy in patients with pheochromocytoma. Anaesth Intensive Care 32(2):224–229CrossRefPubMed Davies MJ, McGlade DP, Banting SW (2004) A comparison of open and laparoscopic approaches to adrenalectomy in patients with pheochromocytoma. Anaesth Intensive Care 32(2):224–229CrossRefPubMed
29.
Zurück zum Zitat Matsuda T, Murota T, Kawakita M (2000) Transperitoneal anterior laparoscopic adrenalectomy: the easiest technique. Biomed Pharmacother 54(Suppl 1):157s–160sCrossRefPubMed Matsuda T, Murota T, Kawakita M (2000) Transperitoneal anterior laparoscopic adrenalectomy: the easiest technique. Biomed Pharmacother 54(Suppl 1):157s–160sCrossRefPubMed
30.
Zurück zum Zitat Janetschek G, Neumann HP (2001) Laparoscopic surgery for pheochromocytoma. Urol Clin N Am 28(1):97–105CrossRef Janetschek G, Neumann HP (2001) Laparoscopic surgery for pheochromocytoma. Urol Clin N Am 28(1):97–105CrossRef
31.
Zurück zum Zitat Prager G, Heinz-Peer G, Passler C, Kaczirek K, Schindl M, Scheuba C, Niederle B (2002) Surgical strategy in adrenal masses. Eur J Radiol 1(1):70–77CrossRef Prager G, Heinz-Peer G, Passler C, Kaczirek K, Schindl M, Scheuba C, Niederle B (2002) Surgical strategy in adrenal masses. Eur J Radiol 1(1):70–77CrossRef
32.
Zurück zum Zitat Col V, de Canniere L, Collard E, Michel L, Donckier J (1999) Laparoscopic adrenalectomy for pheochromocytoma: endocrinological assestment. Clin Endocrinol (Oxf) 50:121–125CrossRef Col V, de Canniere L, Collard E, Michel L, Donckier J (1999) Laparoscopic adrenalectomy for pheochromocytoma: endocrinological assestment. Clin Endocrinol (Oxf) 50:121–125CrossRef
34.
Zurück zum Zitat Linos DA, Stylopoulos N, Boukis M, Souvatzoglou A, Raptis S, Papadimitriou J (1997) Anterior, posterior, or laparoscopic approach for the management of adrenal diseases? Am J Surg 173(2):120–125CrossRefPubMed Linos DA, Stylopoulos N, Boukis M, Souvatzoglou A, Raptis S, Papadimitriou J (1997) Anterior, posterior, or laparoscopic approach for the management of adrenal diseases? Am J Surg 173(2):120–125CrossRefPubMed
35.
Zurück zum Zitat Hisano M, Vicentini FC, Srougi M (2012) Retroperitoneoscopic adrenalectomy in pheochromocytoma. Clinics (Sao Paulo) 67(Suppl 1):161–167CrossRef Hisano M, Vicentini FC, Srougi M (2012) Retroperitoneoscopic adrenalectomy in pheochromocytoma. Clinics (Sao Paulo) 67(Suppl 1):161–167CrossRef
Metadaten
Titel
Is laparoscopic left adrenalectomy with the anterior submesocolic approach for Conn’s or Cushing’s syndrome equally safe and effective as the lateral and anterior ones?
verfasst von
Andrea Balla
Silvia Quaresima
Livia Palmieri
Monica Ortenzi
Emilia Sbardella
Giulia Puliani
Andrea M. Isidori
Mario Guerrieri
Alessandro M. Paganini
Publikationsdatum
19.11.2018
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 9/2019
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-018-6601-6

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