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Erschienen in: International Journal of Clinical Oncology 2/2016

22.09.2015 | Original Article

Is scintigraphy necessary to detect migration of 125I seeds after brachytherapy for early prostate cancer?

verfasst von: Yu Odagaki, Makoto Ohori, Mana Yoshimura, Jun Nakshima, Yoshio Ohno, Ryuji Mikami, Hidetsugu Nakayama, Koichi Tokuuye, Masaaki Tachibana

Erschienen in: International Journal of Clinical Oncology | Ausgabe 2/2016

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Abstract

Background

We investigated whether scintigraphy was superior to radiography for detecting migrated seeds after brachytherapy for prostate cancer.

Methods

We studied 57 patients with early prostate cancer who were treated with free 125I transperineal brachytherapy. Scintigraphy was used to detect seed migration on postoperative day (POD) 1, radiography was used on POD 2, and both tests were used on POD 30.

Results

The total number of implanted seeds in this study was 3,753 in 57 patients. Overall, there were 19 seed migrations in 12 patients. On POD 1, there were 4 seed migrations in 4 patients that were detected by scintigraphy. On POD 2, there were 10 seed migrations in 9 patients that were detected by radiography. On POD 30, 17 seed migrations were detected in 10 patients by radiography and 18 seeds migrations were detected by scintigraphy. However, 1 seed migration which was located outside of the detectable range of radiography was detected only by scintigraphy.

Conclusions

Both scintigraphy and radiography have similar abilities to detect migrated seeds 1 month after 125I brachytherapy for prostate cancer. While both tests have advantages and disadvantages, it is reasonable to only use radiography if scintigraphy is not available.
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Metadaten
Titel
Is scintigraphy necessary to detect migration of 125I seeds after brachytherapy for early prostate cancer?
verfasst von
Yu Odagaki
Makoto Ohori
Mana Yoshimura
Jun Nakshima
Yoshio Ohno
Ryuji Mikami
Hidetsugu Nakayama
Koichi Tokuuye
Masaaki Tachibana
Publikationsdatum
22.09.2015
Verlag
Springer Japan
Erschienen in
International Journal of Clinical Oncology / Ausgabe 2/2016
Print ISSN: 1341-9625
Elektronische ISSN: 1437-7772
DOI
https://doi.org/10.1007/s10147-015-0901-9

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