nach oben

Digestive Diseases and Sciences

Erschienen in:

21.07.2021 | Editorial

Is the APEX Score the Pinnacle of Predictive Scoring Systems of Disease Flare in Crohn’s Patients with Documented Mucosal Healing?

verfasst von: Georgios I. Tsiaoussis, Eirini Christaki

Erschienen in: Digestive Diseases and Sciences | Ausgabe 4/2022

Einloggen, um Zugang zu erhalten

Excerpt

Crohn’s disease (CD) is a chronic relapsing immune-mediated disease affecting the gastrointestinal tract. Effective disease management is dependent on regularly assessing patients with CD for disease recurrence, which is defined according to clinical, radiographic, serologic, and endoscopic criteria. Since approximately 20% of patients with CD have disease limited to the small intestine and since the entire length of the small intestine cannot be visualized endoscopically, these investigations are often inconclusive. In these instances, a small bowel capsule endoscopy (SBCE) is needed to establish the diagnosis or to diagnoses a recurrence of small bowel CD [1]. …

Goran L, Negreanu AM, Stemate A, Negreanu L. Capsule endoscopy: Current status and role in Crohn’s disease. World J Gastrointest Endosc. 2018;10:184–192. https://doi.org/10.4253/wjge.v10.i9.184.CrossRefPubMedPubMedCentral

Peyrin-Biroulet L, Sandborn W, Sands BE et al. Selecting therapeutic targets in inflammatory bowel disease (STRIDE): Determining therapeutic goals for treat-to-target. Am J Gastroenterol. 2015;110:1324–38. https://doi.org/10.1038/ajg.2015.233.CrossRefPubMed

Kopylov U, Nemeth A, Koulaouzidis A et al. Small bowel capsule endoscopy in the management of established Crohn’s disease: clinical impact, safety, and correlation with inflammatory biomarkers. Inflamm Bowel Dis. 2015;21:93–100. https://doi.org/10.1097/MIB.0000000000000255.CrossRefPubMed

Dionisio PM, Gurudu SR, Leighton JA, et al. Capsule endoscopy has a significantly higher diagnostic yield in patients with suspected and established small-bowel Crohn’s disease: A meta-analysis. Am J Gastroenterol. 2010;105:1240-8 (quiz 1249). https://doi.org/10.1038/ajg.2009.713.CrossRefPubMed

Lorenzo-Zúñiga V, de Vega VM, Domènech E, Cabré E, Mañosa M, Boix J. Impact of capsule endoscopy findings in the management of Crohn’s Disease. Dig Dis Sci. 2010;55:411–4. https://doi.org/10.1007/s10620-009-0758-8.CrossRefPubMed

Enns RA, Hookey L, Armstrong D et al. Clinical practice guidelines for the use of video capsule endoscopy. Gastroenterology. 2017;152:497–514. https://doi.org/10.1053/j.gastro.2016.12.032.CrossRefPubMed

Lazarev M, Huang C, Bitton A et al. Relationship between proximal Crohn’s disease location and disease behavior and surgery: A cross-sectional study of the IBD Genetics Consortium. Am J Gastroenterol. 2013;108:106–12. https://doi.org/10.1038/ajg.2012.389.CrossRefPubMed

Flamant M, Trang C, Maillard O et al. The prevalence and outcome of jejunal lesions visualized by small bowel capsule endoscopy in Crohn’s disease. Inflamm Bowel Dis. 2013;19:1390–6. https://doi.org/10.1097/MIB.0b013e31828133c1.CrossRefPubMed

Ben-Horin S, Lahat A, Lahat M M, et al. P392 Comprehensive video capsule endoscopy-based monitoring predicts short and long-term risk of disease flares in small bowel Crohn’s disease: A prospective cohort study. J Crohn’s Colitis. 2018;12:S302–S303.CrossRef

10.

Macedo Silva V, Freitas M, Boal Carvalho et al. APEX score: Predicting flares in small-bowel Crohn’s disease after mucosal healing. Dig Dis Sci. (Epub ahead of print). https://doi.org/10.1007/s10620-021-07148-2.

Titel: Is the APEX Score the Pinnacle of Predictive Scoring Systems of Disease Flare in Crohn’s Patients with Documented Mucosal Healing?
verfasst von: Georgios I. Tsiaoussis
Eirini Christaki
Publikationsdatum: 21.07.2021
Verlag: Springer US
Erschienen in: Digestive Diseases and Sciences / Ausgabe 4/2022
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI: https://doi.org/10.1007/s10620-021-07154-4

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

22.04.2024 | DGIM 2024 | Kongressbericht | Nachrichten

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Is the APEX Score the Pinnacle of Predictive Scoring Systems of Disease Flare in Crohn’s Patients with Documented Mucosal Healing?

Excerpt

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Krebspatienten impfen: Was? Wen? Und wann nicht?

Nierenultraschall: Tipps vom Profi

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

„KI sieht, was wir nicht sehen“

Update Innere Medizin

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2022

Acute Diverticulitis in Young Patients: A Review of the Changing Epidemiology and Etiology

Association Between Portal Vein Thrombosis and Pouchitis in Patients with Ulcerative Colitis

Baseline Histological Findings Do Not Predict the Risk of Subsequent Extension in Patients with Limited Ulcerative Colitis

Apex Score: Predicting Flares in Small-Bowel Crohn’s Disease After Mucosal Healing

Efficacy of a Modified Training Program of Adaptive Biofeedback Therapy for Dyssynergic Defecation in Patients with Chronic Constipation

IgA Deficiency Is Not Systematically Ruled Out in Patients Undergoing Celiac Disease Testing

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Krebspatienten impfen: Was? Wen? Und wann nicht?

Nierenultraschall: Tipps vom Profi

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

„KI sieht, was wir nicht sehen“

Update Innere Medizin