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01.11.2010 | Case Report

Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis

verfasst von: Hideki Nakamura, Akitomo Okada, Atsushi Kawakami, Satoshi Yamasaki, Hiroaki Ida, Masakatsu Motomura, Daisuke Imanishi, Katsumi Eguchi

Erschienen in: Rheumatology International | Ausgabe 12/2010

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Abstract

A 47-year-old woman who had been treated for systemic lupus erythematosus (SLE) with myasthenia gravis (MG) was admitted to our hospital with acute onset of severe anemia after administration of isoniazid. Pure red cell aplasia (PRCA) was confirmed by elevated serum iron levels, reticulocytopenia and bone marrow aspiration showing a remarkable reduction of erythroblasts. Finally, cyclosporine A successfully improved PRCA. Although both SLE and MG have the potential complication of PRCA, we report here a case of isoniazid-triggered PRCA.

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Titel: Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis
verfasst von: Hideki Nakamura
Akitomo Okada
Atsushi Kawakami
Satoshi Yamasaki
Hiroaki Ida
Masakatsu Motomura
Daisuke Imanishi
Katsumi Eguchi
Publikationsdatum: 01.11.2010
Verlag: Springer-Verlag
Erschienen in: Rheumatology International / Ausgabe 12/2010
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-009-1113-2

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Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis

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