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Erschienen in: AIDS and Behavior 11/2018

16.06.2018 | Original Paper

“It Was Not My Aim to Sleep There”: The Impact of Timing and Location of Sex on Adherence to Coitally-Dependent HIV Pre-exposure Prophylaxis

verfasst von: Fiona Scorgie, Jonathan Stadler, Deborah Baron, Susan Ju, Tshepiso Ikaneng, Zonke Mabude, Sylvia Makgopa, Matshidiso A. Malefo, Kgahlisho N. Manenzhe, Thulani Mazibuko, Hilda Ntjana, Busi Nkala, Thesla Palanee-Phillips, Glenda Gray, Helen Rees, Sinead Delany-Moretlwe

Erschienen in: AIDS and Behavior | Ausgabe 11/2018

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Abstract

The FACTS 001 trial found that vaginal pre- and post-coital application of 1% tenofovir gel did not prevent HIV-1 infection amongst young South African women. The trial included a multi-faceted approach to adherence support and collected objective and self-reported adherence measures. Using qualitative data collected from a random sub-set of FACTS 001 participants (135 in-depth interviews at product discontinuation and 13 focus group discussions at dissemination of trial results), we explore the importance of ‘place’ and ‘timing’ in shaping acts of sexual intimacy and product adherence. Demographically, this qualitative sub-sample is similar to the trial cohort of predominantly young, unemployed women living with parents or other family members. Sexual intimacy was largely unpredictable and happened across multiple locations in which women had limited privacy, autonomy, or control over the timing of sex. This made adherence to the dosing strategy challenging. Findings may inform the development of future event-driven pre-exposure prophylaxis regimens or products.
Literatur
1.
Zurück zum Zitat Obiero J, Mwethera PG, Wiysonge CS. Topical microbicides for prevention of sexually transmitted infections. Cochrane Database Syst Rev. 2012;6:CD007961. Obiero J, Mwethera PG, Wiysonge CS. Topical microbicides for prevention of sexually transmitted infections. Cochrane Database Syst Rev. 2012;6:CD007961.
2.
Zurück zum Zitat Shattock RJ, Rosenberg Z. Microbicides: topical prevention against HIV. Cold Spring Harb Perspect Med. 2012;2(2):a007385.CrossRef Shattock RJ, Rosenberg Z. Microbicides: topical prevention against HIV. Cold Spring Harb Perspect Med. 2012;2(2):a007385.CrossRef
3.
Zurück zum Zitat Mantell JE, Dworkin SL, Exner TM, Hoffman S, Smit JA, Susser I. The promises and limitations of female-initiated methods of HIV/STI protection. Soc Sci Med. 2006;63:1998–2009.CrossRef Mantell JE, Dworkin SL, Exner TM, Hoffman S, Smit JA, Susser I. The promises and limitations of female-initiated methods of HIV/STI protection. Soc Sci Med. 2006;63:1998–2009.CrossRef
4.
Zurück zum Zitat Bell SE. Sexual synthetics: women, science and microbicides. In: Casper MJ, editor. Synthetic planet: chemical politics and the hazards of modern life. London: Routledge; 2003. p. 197–211. Bell SE. Sexual synthetics: women, science and microbicides. In: Casper MJ, editor. Synthetic planet: chemical politics and the hazards of modern life. London: Routledge; 2003. p. 197–211.
5.
Zurück zum Zitat Woodsong C, MacQueen K, Rivet Amico K, et al. Microbicide clinical trial adherence: insights for introduction. J Int AIDS Soc. 2013;16:18505.CrossRef Woodsong C, MacQueen K, Rivet Amico K, et al. Microbicide clinical trial adherence: insights for introduction. J Int AIDS Soc. 2013;16:18505.CrossRef
6.
Zurück zum Zitat Karim QA, Karim SSA, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329:1168–74.CrossRef Karim QA, Karim SSA, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329:1168–74.CrossRef
7.
Zurück zum Zitat Marrazzo JM, Ramjee G, Richardson BA, et al. Tenofovir-based preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2015;372(6):509–18.CrossRef Marrazzo JM, Ramjee G, Richardson BA, et al. Tenofovir-based preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2015;372(6):509–18.CrossRef
8.
Zurück zum Zitat Rees H, Delaney-Moretlwe S, Lombard C, et al.: Facts 001 Phase III Trial of Pericoital Tenofovir 1% Gel for HIV Prevention in Women. Conference on Retroviruses and Opportunistic Infections (CROI). Seattle, WA, USA. Abstract 26LB2015. Rees H, Delaney-Moretlwe S, Lombard C, et al.: Facts 001 Phase III Trial of Pericoital Tenofovir 1% Gel for HIV Prevention in Women. Conference on Retroviruses and Opportunistic Infections (CROI). Seattle, WA, USA. Abstract 26LB2015.
9.
Zurück zum Zitat Stadler J, Saethre E. Blockage and flow: intimate experiences of condoms and microbicides in a South African clinical trial. Cult Health Sex. 2011;13(1):31–44.CrossRef Stadler J, Saethre E. Blockage and flow: intimate experiences of condoms and microbicides in a South African clinical trial. Cult Health Sex. 2011;13(1):31–44.CrossRef
10.
Zurück zum Zitat Lees S. Emergent HIV technology: urban Tanzanian women’s narratives of medical research, microbicides and sexuality. Cult Health Sex. 2014;15:1–16. Lees S. Emergent HIV technology: urban Tanzanian women’s narratives of medical research, microbicides and sexuality. Cult Health Sex. 2014;15:1–16.
11.
Zurück zum Zitat Montgomery CM, Gafos M, Lees S, et al. Re-framing microbicide acceptability: findings from the MDP301 trial. Cult Health Sex. 2010;12(6):649–62.CrossRef Montgomery CM, Gafos M, Lees S, et al. Re-framing microbicide acceptability: findings from the MDP301 trial. Cult Health Sex. 2010;12(6):649–62.CrossRef
12.
Zurück zum Zitat van der Straten A, Stadler J, Montgomery E, et al. Women’s experiences with oral and vaginal pre-exposure prophylaxis: the VOICE-C qualitative study in Johannesburg, South Africa. PLoS ONE. 2014;9(2):e89118.CrossRef van der Straten A, Stadler J, Montgomery E, et al. Women’s experiences with oral and vaginal pre-exposure prophylaxis: the VOICE-C qualitative study in Johannesburg, South Africa. PLoS ONE. 2014;9(2):e89118.CrossRef
13.
Zurück zum Zitat Ware NC, Wyatt MA, Haberer JE, et al. What’s love got to do with it? Explaining adherence to oral antiretroviral pre-exposure prophylaxis for HIV-serodiscordant couples. J Acquir Immune Defic Syndr. 2012;59(5):463–8.CrossRef Ware NC, Wyatt MA, Haberer JE, et al. What’s love got to do with it? Explaining adherence to oral antiretroviral pre-exposure prophylaxis for HIV-serodiscordant couples. J Acquir Immune Defic Syndr. 2012;59(5):463–8.CrossRef
14.
Zurück zum Zitat Amico KR, Mansoor LE, Corneli A, Torjesen K, van der Straten A. Adherence support approaches in biomedical HIV prevention trials: experiences, insights and future directions from four multisite prevention trials. AIDS Behav. 2013;17(6):2143–55.CrossRef Amico KR, Mansoor LE, Corneli A, Torjesen K, van der Straten A. Adherence support approaches in biomedical HIV prevention trials: experiences, insights and future directions from four multisite prevention trials. AIDS Behav. 2013;17(6):2143–55.CrossRef
15.
Zurück zum Zitat Corneli AL, McKenna K, Headley J, et al. A descriptive analysis of perceptions of HIV risk and worry about acquiring HIV among FEM-PrEP participants who seroconverted in Bondo, Kenya, and Pretoria, South Africa. J Int AIDS Soc. 2014;17(3 Suppl 2):19152.PubMedPubMedCentral Corneli AL, McKenna K, Headley J, et al. A descriptive analysis of perceptions of HIV risk and worry about acquiring HIV among FEM-PrEP participants who seroconverted in Bondo, Kenya, and Pretoria, South Africa. J Int AIDS Soc. 2014;17(3 Suppl 2):19152.PubMedPubMedCentral
16.
Zurück zum Zitat Corneli AL, Deese J, Wang M, et al. FEM-PrEP: adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis. J Acquir Immune Defic Syndr. 2014;66(3):324–31.CrossRef Corneli AL, Deese J, Wang M, et al. FEM-PrEP: adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis. J Acquir Immune Defic Syndr. 2014;66(3):324–31.CrossRef
17.
Zurück zum Zitat Stadler J, Saethre E. Rumours about blood and reimbursements in a microbicide gel trial. Afr J AIDS Res. 2010;9(4):345–53.CrossRef Stadler J, Saethre E. Rumours about blood and reimbursements in a microbicide gel trial. Afr J AIDS Res. 2010;9(4):345–53.CrossRef
18.
Zurück zum Zitat Succopa SM, MacQueen KM, van Loggerenberg F, Majola N, Abdool Karim Q, Abdool Karim SS. Trial participation disclosure and gel use behavior in the CAPRISA 004 tenofovir gel trial. AIDS Care. 2014;26(12):1521–5.CrossRef Succopa SM, MacQueen KM, van Loggerenberg F, Majola N, Abdool Karim Q, Abdool Karim SS. Trial participation disclosure and gel use behavior in the CAPRISA 004 tenofovir gel trial. AIDS Care. 2014;26(12):1521–5.CrossRef
19.
Zurück zum Zitat Montgomery ET, van der Straten A, Stadler J, et al. Male partner influence on women’s HIV prevention trial participation and use of pre-exposure prophylaxis: the importance of “Understanding”. AIDS Behav. 2015;19(5):784–93.CrossRef Montgomery ET, van der Straten A, Stadler J, et al. Male partner influence on women’s HIV prevention trial participation and use of pre-exposure prophylaxis: the importance of “Understanding”. AIDS Behav. 2015;19(5):784–93.CrossRef
20.
Zurück zum Zitat Montgomery C, Lees S, Stadler J, et al. The role of partnership dynamics in determining the acceptability of condoms and microbicides. AIDS Care. 2008;20(6):733–40.CrossRef Montgomery C, Lees S, Stadler J, et al. The role of partnership dynamics in determining the acceptability of condoms and microbicides. AIDS Care. 2008;20(6):733–40.CrossRef
21.
Zurück zum Zitat MacQueen KM, Dlamini S, Perry B, et al. Social context of adherence in an open-label 1% tenofovir gel trial: gender dynamics and disclosure in KwaZulu-Natal, South Africa. AIDS Behav. 2016;20:2682–91.CrossRef MacQueen KM, Dlamini S, Perry B, et al. Social context of adherence in an open-label 1% tenofovir gel trial: gender dynamics and disclosure in KwaZulu-Natal, South Africa. AIDS Behav. 2016;20:2682–91.CrossRef
22.
Zurück zum Zitat Stadler J, Delany-Moretlwe S, Palanee T, Rees H. Hidden harms: women’s narratives of intimate partner violence in a microbicide trial, South Africa. Soc Sci Med. 2014;110:49–55.CrossRef Stadler J, Delany-Moretlwe S, Palanee T, Rees H. Hidden harms: women’s narratives of intimate partner violence in a microbicide trial, South Africa. Soc Sci Med. 2014;110:49–55.CrossRef
23.
Zurück zum Zitat Montgomery E, van der Straten A, Stadler J, et al. Male partner influence on women’s HIV prevention trial participation and use of pre-exposure prophylaxis: the importance of “Understanding”. AIDS Behav. 2014;2014(11/22):1–10. Montgomery E, van der Straten A, Stadler J, et al. Male partner influence on women’s HIV prevention trial participation and use of pre-exposure prophylaxis: the importance of “Understanding”. AIDS Behav. 2014;2014(11/22):1–10.
25.
Zurück zum Zitat Decker MR, Peitzmeier S, Olumide A, et al. Prevalence and health impact of intimate partner violence and non-partner sexual violence among female adolescents aged 15–19 years in vulnerable urban environments: a multi-country study. J Adolesc Health. 2014;55(6 Suppl):S58–67.CrossRef Decker MR, Peitzmeier S, Olumide A, et al. Prevalence and health impact of intimate partner violence and non-partner sexual violence among female adolescents aged 15–19 years in vulnerable urban environments: a multi-country study. J Adolesc Health. 2014;55(6 Suppl):S58–67.CrossRef
26.
Zurück zum Zitat Jewkes RK, Dunkle K, Nduna M, Shai N. Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study. Lancet. 2010;376(41):e8. Jewkes RK, Dunkle K, Nduna M, Shai N. Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study. Lancet. 2010;376(41):e8.
27.
Zurück zum Zitat Posel D. Have migration patterns in post-apartheid South Africa changed? J Interdiscip Econ. 2004;15:277–92.CrossRef Posel D. Have migration patterns in post-apartheid South Africa changed? J Interdiscip Econ. 2004;15:277–92.CrossRef
28.
Zurück zum Zitat Murray MJ. Taming the disorderly city: the spatial landscape of Johannesburg after apartheid. Ithaca and London: Cornell University Press; 2008. Murray MJ. Taming the disorderly city: the spatial landscape of Johannesburg after apartheid. Ithaca and London: Cornell University Press; 2008.
29.
Zurück zum Zitat Wand H, Ramjee G. Targeting the hotspots: investigating spatial and demographic variations in HIV infection in small communities in South Africa. J Int AIDS Soc. 2010;13(41):13–41. Wand H, Ramjee G. Targeting the hotspots: investigating spatial and demographic variations in HIV infection in small communities in South Africa. J Int AIDS Soc. 2010;13(41):13–41.
30.
Zurück zum Zitat Pitpitan EV, Kalichman SC. Reducing HIV risks in the places where people drink: prevention interventions in alcohol venues. AIDS Behav. 2016;20(Suppl 1):S119–33.CrossRef Pitpitan EV, Kalichman SC. Reducing HIV risks in the places where people drink: prevention interventions in alcohol venues. AIDS Behav. 2016;20(Suppl 1):S119–33.CrossRef
31.
Zurück zum Zitat Govender EM, Mansoor LE, Abdool Karim Q. Influences of geo-spatial location on pre-exposure prophylaxis use in South Africa: positioning microbicides for better product uptake. AIDS Care. 2017;29(6):734–40.CrossRef Govender EM, Mansoor LE, Abdool Karim Q. Influences of geo-spatial location on pre-exposure prophylaxis use in South Africa: positioning microbicides for better product uptake. AIDS Care. 2017;29(6):734–40.CrossRef
32.
Zurück zum Zitat Friedland BA, Stoner M, Chau MM, et al. Baseline predictors of high adherence to a coitally dependent microbicide gel based on an objective marker of use: findings from the carraguard phase 3 trial. AIDS Behav. 2016;20(11):2565–77.CrossRef Friedland BA, Stoner M, Chau MM, et al. Baseline predictors of high adherence to a coitally dependent microbicide gel based on an objective marker of use: findings from the carraguard phase 3 trial. AIDS Behav. 2016;20(11):2565–77.CrossRef
33.
Zurück zum Zitat Govender E, Mansoor L, MacQueen K, Abdool Karim Q. Secrecy, empowerment and protection: positioning PrEP in KwaZulu-Natal, South Africa. Culture, health & sexuality. 2017;19:1268–85.CrossRef Govender E, Mansoor L, MacQueen K, Abdool Karim Q. Secrecy, empowerment and protection: positioning PrEP in KwaZulu-Natal, South Africa. Culture, health & sexuality. 2017;19:1268–85.CrossRef
34.
Zurück zum Zitat Swartz A, Colvin C, Harrison A. The Cape Town boyfriend and the Joburg boyfriend: women’s sexual partnerships and social networks in Khayelitsha, Cape Town. Soc Dyn. 2016;42(2):237–52.CrossRef Swartz A, Colvin C, Harrison A. The Cape Town boyfriend and the Joburg boyfriend: women’s sexual partnerships and social networks in Khayelitsha, Cape Town. Soc Dyn. 2016;42(2):237–52.CrossRef
35.
Zurück zum Zitat Flowers P, Marriott C, Hart G. ‘The bars, the bogs, and the bushes’: the impact of locale on sexual cultures. Cult Health Sex. 2000;2(1):69–86.CrossRef Flowers P, Marriott C, Hart G. ‘The bars, the bogs, and the bushes’: the impact of locale on sexual cultures. Cult Health Sex. 2000;2(1):69–86.CrossRef
36.
Zurück zum Zitat O’Halloran AB, Armstrong G, Medhi GK, Sono CZ, Mahanta J, Kermode M. HIV risks vary according to type of sex work in a cross-sectional survey from Nagaland, India. BMC Women’s Health. 2014;14:133.CrossRef O’Halloran AB, Armstrong G, Medhi GK, Sono CZ, Mahanta J, Kermode M. HIV risks vary according to type of sex work in a cross-sectional survey from Nagaland, India. BMC Women’s Health. 2014;14:133.CrossRef
37.
Zurück zum Zitat UNAIDS.: Empower Young Women and Adolescent Girls: Fast-tracking the End of the AIDS Epidemic in Africa. Geneva: UNAIDS;2015. UNAIDS.: Empower Young Women and Adolescent Girls: Fast-tracking the End of the AIDS Epidemic in Africa. Geneva: UNAIDS;2015.
38.
Zurück zum Zitat Stern E, Cooper D. Experiences and conceptualizations of sexual debut from the narratives of South African men and women in the context of HIV/AIDS. Afr J AIDS Res. 2014;13(2):121–31.CrossRef Stern E, Cooper D. Experiences and conceptualizations of sexual debut from the narratives of South African men and women in the context of HIV/AIDS. Afr J AIDS Res. 2014;13(2):121–31.CrossRef
39.
Zurück zum Zitat Madiba S, Ngwenya N. Cultural practices, gender inequality and inconsistent condom use increase vulnerability to HIV infection: narratives from married and cohabiting women in rural communities in Mpumalanga province, South Africa. Glob Health Action. 2017;10(Suppl. 2):1341597.CrossRef Madiba S, Ngwenya N. Cultural practices, gender inequality and inconsistent condom use increase vulnerability to HIV infection: narratives from married and cohabiting women in rural communities in Mpumalanga province, South Africa. Glob Health Action. 2017;10(Suppl. 2):1341597.CrossRef
40.
Zurück zum Zitat Wolff B, Blanc AK, Gage AJ. Who decides? Women’s status and negotiation of sex in Uganda. Cult Health Sex. 2000;2(3):303–22.CrossRef Wolff B, Blanc AK, Gage AJ. Who decides? Women’s status and negotiation of sex in Uganda. Cult Health Sex. 2000;2(3):303–22.CrossRef
41.
Zurück zum Zitat Crankshaw O, Gilbert A, Morris A. Backyard Soweto. Int J Urban Reg Res. 2000;24(4):841–57.CrossRef Crankshaw O, Gilbert A, Morris A. Backyard Soweto. Int J Urban Reg Res. 2000;24(4):841–57.CrossRef
42.
Zurück zum Zitat Department of Health Province of KwaZulu Natal.: District Health Plan 2015/2016—Umgungundlovu Health District. Pietermaritzburg 2015. Department of Health Province of KwaZulu Natal.: District Health Plan 2015/2016—Umgungundlovu Health District. Pietermaritzburg 2015.
43.
Zurück zum Zitat Department of Health Province of KwaZulu Natal.: District Health Plan 2015/2016—Uthukela Health District. Pietermaritzburg 2015. Department of Health Province of KwaZulu Natal.: District Health Plan 2015/2016—Uthukela Health District. Pietermaritzburg 2015.
44.
Zurück zum Zitat Mudhune S, Delany-Moretlwe S, Baron D, et al.: Motivating, measuring and monitoring adherence in the FACTS 001 tenofovir gel microbicide study Paper presented at: HIV Research For Prevention 2014; Cape Town. Mudhune S, Delany-Moretlwe S, Baron D, et al.: Motivating, measuring and monitoring adherence in the FACTS 001 tenofovir gel microbicide study Paper presented at: HIV Research For Prevention 2014; Cape Town.
45.
Zurück zum Zitat Glaser BG, Strauss AL. The discovery of grounded theory: strategies for qualitative research. New York: Aldine Transaction; 1967. Glaser BG, Strauss AL. The discovery of grounded theory: strategies for qualitative research. New York: Aldine Transaction; 1967.
46.
Zurück zum Zitat Abdool Karim Q, Abdool Karim SS, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329(5996):1168–74.CrossRef Abdool Karim Q, Abdool Karim SS, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329(5996):1168–74.CrossRef
47.
Zurück zum Zitat Braunstein S, van de Wijgert J. Preferences and practices related to vaginal lubrication: implications for microbicide acceptability and clinical testing. J Women’s Health. 2005;14(5):424–33.CrossRef Braunstein S, van de Wijgert J. Preferences and practices related to vaginal lubrication: implications for microbicide acceptability and clinical testing. J Women’s Health. 2005;14(5):424–33.CrossRef
48.
Zurück zum Zitat Ray S, Gumbo N, Mbizvo M. Local voices: what some Harare men say about preparation for sex. Reprod Health Matt. 1996;7:63–73. Ray S, Gumbo N, Mbizvo M. Local voices: what some Harare men say about preparation for sex. Reprod Health Matt. 1996;7:63–73.
49.
Zurück zum Zitat Scorgie F, Busisiwe K, Smit JA, Manzini N, Chersich MF, Preston-Whyte EM. In search of sexual pleasure and fidelity: vaginal practices in KwaZulu-Natal, South Africa. Cult Health Sex. 2009;11(3):267–83.CrossRef Scorgie F, Busisiwe K, Smit JA, Manzini N, Chersich MF, Preston-Whyte EM. In search of sexual pleasure and fidelity: vaginal practices in KwaZulu-Natal, South Africa. Cult Health Sex. 2009;11(3):267–83.CrossRef
50.
Zurück zum Zitat van der Straten A, Cheng H, Mensch B, et al. Evaluation of 3 approaches for assessing adherence to vaginal gel application in clinical trials. Sex Transm Dis. 2013;40(12):950–6.CrossRef van der Straten A, Cheng H, Mensch B, et al. Evaluation of 3 approaches for assessing adherence to vaginal gel application in clinical trials. Sex Transm Dis. 2013;40(12):950–6.CrossRef
51.
Zurück zum Zitat Agot K, Taylor D, Corneli AL, et al. Accuracy of self-report and pill-count measures of adherence in the FEM-PrEP clinical trial: implications for future HIV-prevention trials. AIDS Behav. 2015;19(5):743–51.CrossRef Agot K, Taylor D, Corneli AL, et al. Accuracy of self-report and pill-count measures of adherence in the FEM-PrEP clinical trial: implications for future HIV-prevention trials. AIDS Behav. 2015;19(5):743–51.CrossRef
52.
Zurück zum Zitat Husnik MJ, Brown ER, Marzinke M, et al. Implementation of a novel adherence monitoring strategy in a phase iii, blinded, placebo-controlled, HIV-1 prevention clinical trial. J Acquir Immune Defic Syndr. 2017;76(3):330–7.CrossRef Husnik MJ, Brown ER, Marzinke M, et al. Implementation of a novel adherence monitoring strategy in a phase iii, blinded, placebo-controlled, HIV-1 prevention clinical trial. J Acquir Immune Defic Syndr. 2017;76(3):330–7.CrossRef
53.
Zurück zum Zitat Statistics South Africa. National and provincial labour market: youth. Pretoria: Statistics South Africa; 2015. Statistics South Africa. National and provincial labour market: youth. Pretoria: Statistics South Africa; 2015.
54.
Zurück zum Zitat Klasen S, Woolard I. Surviving unemployment without state support: unemployment and household formation in South Africa. Bonn: Institute for the Study of Labour; 2000. Klasen S, Woolard I. Surviving unemployment without state support: unemployment and household formation in South Africa. Bonn: Institute for the Study of Labour; 2000.
55.
Zurück zum Zitat Jewkes R, Morrell R. Sexuality and the limits of agency among South African teenage women: theorising femininities and their connections to HIV risk practices. Soc Sci Med. 2012;74(11):1729–37.CrossRef Jewkes R, Morrell R. Sexuality and the limits of agency among South African teenage women: theorising femininities and their connections to HIV risk practices. Soc Sci Med. 2012;74(11):1729–37.CrossRef
56.
Zurück zum Zitat Gevers A, Jewkes A, Mathews C, Flisher A. ‘I think it’s about experiencing, like, life’: a qualitative exploration of contemporary adolescent intimate relationships in South Africa. Cult Health Sex. 2012;14(10):1125–37.CrossRef Gevers A, Jewkes A, Mathews C, Flisher A. ‘I think it’s about experiencing, like, life’: a qualitative exploration of contemporary adolescent intimate relationships in South Africa. Cult Health Sex. 2012;14(10):1125–37.CrossRef
57.
Zurück zum Zitat Saethre E, Stadler J. Gelling medical knowledge: innovative pharmaceuticals, experience, and perceptions of efficacy. Anthropol Med. 2010;17(1):99–111.CrossRef Saethre E, Stadler J. Gelling medical knowledge: innovative pharmaceuticals, experience, and perceptions of efficacy. Anthropol Med. 2010;17(1):99–111.CrossRef
58.
Zurück zum Zitat Mykhalovskiy E, Mccoy L, Bresalier M. Compliance/adherence, HIV, and the critique of medical power. Soc Theor Health. 2004;2(4):315–40.CrossRef Mykhalovskiy E, Mccoy L, Bresalier M. Compliance/adherence, HIV, and the critique of medical power. Soc Theor Health. 2004;2(4):315–40.CrossRef
59.
Zurück zum Zitat Cooper M, Waldby C. Clinical labor: tissue donors and research subjects in the global bioeconomy. Durham: Duke University Press; 2014.CrossRef Cooper M, Waldby C. Clinical labor: tissue donors and research subjects in the global bioeconomy. Durham: Duke University Press; 2014.CrossRef
60.
Zurück zum Zitat Andersen RS, Risør MB. The importance of contextualization. Anthropological reflections on descriptive analysis, its limitations and implications. Anthropol Med. 2014;21(3):345–56.CrossRef Andersen RS, Risør MB. The importance of contextualization. Anthropological reflections on descriptive analysis, its limitations and implications. Anthropol Med. 2014;21(3):345–56.CrossRef
61.
Zurück zum Zitat Mngadi KT, Maarschalk S, Grobler AC, et al. Disclosure of microbicide gel use to sexual partners: influence on adherence in the CAPRISA 004 trial. AIDS Behav. 2014;18(5):849–54.CrossRef Mngadi KT, Maarschalk S, Grobler AC, et al. Disclosure of microbicide gel use to sexual partners: influence on adherence in the CAPRISA 004 trial. AIDS Behav. 2014;18(5):849–54.CrossRef
62.
Zurück zum Zitat Shisana O, Rehle T, Simbayi L, et al. South African national HIV Prevalence, Incidence and Behaviour Survey, 2012. Cape Town: HSRC Press; 2014. Shisana O, Rehle T, Simbayi L, et al. South African national HIV Prevalence, Incidence and Behaviour Survey, 2012. Cape Town: HSRC Press; 2014.
Metadaten
Titel
“It Was Not My Aim to Sleep There”: The Impact of Timing and Location of Sex on Adherence to Coitally-Dependent HIV Pre-exposure Prophylaxis
verfasst von
Fiona Scorgie
Jonathan Stadler
Deborah Baron
Susan Ju
Tshepiso Ikaneng
Zonke Mabude
Sylvia Makgopa
Matshidiso A. Malefo
Kgahlisho N. Manenzhe
Thulani Mazibuko
Hilda Ntjana
Busi Nkala
Thesla Palanee-Phillips
Glenda Gray
Helen Rees
Sinead Delany-Moretlwe
Publikationsdatum
16.06.2018
Verlag
Springer US
Erschienen in
AIDS and Behavior / Ausgabe 11/2018
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-018-2195-1

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