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European Journal of Clinical Microbiology & Infectious Diseases OnlineFirst articles

05.10.2022 | Original Article

Comparison of infections with respiratory syncytial virus between children and adults: a multicenter surveillance from 2015 to 2019 in Beijing, China

The objective of this study is to investigate the epidemiological and clinical characteristics of the acute respiratory tract infections (ARTI) caused by respiratory syncytial virus (RSV) among the population of all age categories in Beijing …

verfasst von:
Ming Luo, Cheng Gong, Yan Zhang, Xue Wang, Yang Liu, Qing Luo, Maozhong Li, Aihua Li, Yiting Wang, Mei Dong, Wenbo Xu, Fang Huang

Open Access 04.10.2022 | Original Article

Determinants and outcomes of bloodstream infections related to obesity

Although obesity is a major healthcare problem that is increasing in many populations worldwide, there are limited studies that have examined its contribution to infectious diseases morbidity and mortality. The aim of this study was to examine the …

verfasst von:
Felicity Edwards, Kate Glen, Patrick N. A. Harris, David L. Paterson, Kevin B. Laupland

Open Access 01.10.2022 | Original Article

The effect of selective decontamination on the intestinal microbiota as measured with IS-pro: a taxonomic classification tool applicable for direct evaluation of intestinal microbiota in clinical routine

Selective decontamination of the digestive tract (SDD) is aimed at elimination of potential pathogenic microorganisms. In this study, the effect of SDD on gut microbiota was evaluated in a large homogenous group of elective colorectal cancer …

verfasst von:
M. L. M. van Doorn-Schepens, G. S. A. Abis, S. J. Oosterling, M. van Egmond, L. Poort, H. B. A. C. Stockmann, H. J. Bonjer, P. H. M. Savelkoul, A. E. Budding

30.09.2022 | Brief Report

Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of …

verfasst von:
Ariel Kenig, Yonatan Oster, Ronit Cohen-Poradosu, Klaris Reisenberg, Anat Wieder-Finesod, Mirit Hershman-Sarafov, Ilana Oren, Gabriel Weber, Ron Dagan, Gili Regev-Yochay, Jacob Strahilevitz

Open Access 30.09.2022 | Original Article

A longitudinal analysis of nosocomial bloodstream infections among preterm neonates

Nosocomial bloodstream infections (NBSIs), commonly due to central-line associated bloodstream infections (CLABSI), contribute substantially to neonatal morbidity and mortality. We aimed to identify longitudinal changes in incidence of NBSI …

verfasst von:
Sophie J. Jansen, Alieke van der Hoeven, Thomas van den Akker, Marieke Veenhof, Erik G. J. von Asmuth, Karin Ellen Veldkamp, Monique Rijken, Martha van der Beek, Vincent Bekker, Enrico Lopriore

26.09.2022 | Original Article

A longitudinal study of Candida bloodstream infections in a Japanese university hospital: species distribution, drug susceptibility, clinical features, and mortality predictors

We aimed to detect possible changes in Candida species distribution over time and to know the antifungal susceptibility profile of isolates obtained from patients with bloodstream infection (BSI) due to this pathogen. Risk factors associated with …

verfasst von:
Hitoshi Tsukamoto, Takashi Higashi, Takaaki Kodawara, Kyohei Watanabe, Yukio Hida, Hiromichi Iwasaki, Nobuyuki Goto

22.09.2022 | Brief Report

Racemose neurocysticercosis simulating tuberculous meningitis

We report a patient with racemose neurocysticercosis, highlighting the diagnostic and management issues. A 37-year-old male had headaches, fever, and seizures for 8 months. He had a positive tuberculin test, cerebrospinal fluid pleocytosis, and …

verfasst von:
Prakash C. Pandey, Jayantee Kalita, Jayesh Sardhara, Neeraj Jain, Pallavi Prasad

Open Access 22.09.2022 | Original Article

Epidemiology, aetiology and clinical characteristics of clostridial bacteraemia: a 6-year population-based observational study of 386 patients

The objective of this study is to provide a population-based clinical, epidemiological and microbiological overview of clostridial bacteraemia. All cases of bacteraemia in the Skåne Region between 2014 and 2019 with a species currently belonging …

verfasst von:
Maaria Sarasoja, Bo Nilson, Daniel Wide, Åsa Lindberg, Gustav Torisson, Karin Holm

17.09.2022 | Original Article

Ancient DNA confirmation of lepromatous leprosy in a skeleton with concurrent osteosarcoma, excavated from the leprosarium of St. Mary Magdalen in Winchester, Hants., UK

To establish a biological profile and disease aetiologies for one of four burials recovered during a Time Team dig at the St. Mary Magdalen leprosarium, Winchester, UK in AD 2000. Osteological techniques were applied to estimate age at death …

verfasst von:
G. Cole, G. M. Taylor, G. R. Stewart, H. Dawson-Hobbis

15.09.2022 | Original Article

Comparison between culture-positive and culture-negative septic shock in patients in the emergency department

Culture results of patients with septic shock affect their management strategies, including antibiotic administration. This study aimed to compare clinical characteristics and outcomes of patients with culture-negative septic shock (CNSS) and …

verfasst von:
Choon-Bing Chua, Chi-Chieh Hung, Yong-Ye Yang, Tsung-Han Wang, Yin-Chou Hsu

Open Access 14.09.2022 | Brief Report

Molecular analysis of OXA-48-producing Escherichia coli in Switzerland from 2019 to 2020

OXA-48-type ß-lactamases are the most prevalent carbapenemase-type in Enterobacterales in Switzerland, predominantly found in Escherichia coli and Klebsiella pneumoniae. Bacteria-producing OXA-48-type enzymes are endemic in some parts of the …

verfasst von:
Jacqueline Findlay, Vincent Perreten, Laurent Poirel, Patrice Nordmann

Open Access 07.04.2022 | Original Article

Antimicrobial susceptibility testing is crucial when treating Finegoldia magna infections

Finegoldia magna is an anaerobic gram-positive bacterium that can cause invasive human infections. Recently, a 52-year-old patient suffering from a periprosthetic joint infection (PJI) due to F. magna was treated with cefepime on hemodialysis; …

verfasst von:
Fabienne Walser, Julia Prinz, Stefan Rahm, Patrick O. Zingg, Stefano Mancini, Frank Imkamp, Reinhard Zbinden, Yvonne Achermann

Open Access 13.12.2021 | Original Article

Carriage of ESBL-producing Enterobacterales in wastewater treatment plant workers and surrounding residents — the AWARE Study

To investigate whether wastewater treatment plant (WWTP) workers and residents living in close proximity to a WWTP have elevated carriage rates of ESBL-producing Enterobacterales, as compared to the general population. From 2018 to 2020, we …

verfasst von:
Daloha Rodríguez-Molina, Fanny Berglund, Hetty Blaak, Carl-Fredrik Flach, Merel Kemper, Luminita Marutescu, Gratiela Pircalabioru Gradisteanu, Marcela Popa, Beate Spießberger, Tobias Weinmann, Laura Wengenroth, Mariana Carmen Chifiriuc, D. G. Joakim Larsson, Dennis Nowak, Katja Radon, Ana Maria de Roda Husman, Andreas Wieser, Heike Schmitt

Open Access 02.12.2021 | Original Article

Diversity of carbapenem-resistant Klebsiella pneumoniae ST14 and emergence of a subgroup with KL64 capsular locus in the Arabian Peninsula

To understand the reasons of successful spread of carbapenem-resistant Klebsiella pneumoniae ST14 (CRKP-ST14) in countries of the Arabian Peninsula, the resistome, capsular locus, carbapenemase carrying plasmid types, and core genome of isolates …

verfasst von:
Shaimaa F. Mouftah, Tibor Pál, Paul G. Higgins, Akela Ghazawi, Youssef Idaghdour, Manaf Alqahtani, Ali S. Omrani, Tahir A. Rizvi, Ágnes Sonnevend

Open Access 17.11.2021 | Original Article

Interplay between IncF plasmids and topoisomerase mutations conferring quinolone resistance in the Escherichia coli ST131 clone: stability and resistance evolution

The Escherichia coli ST131 H30-Rx subclone vehicles CTX-M-15 plasmids and mutations in gyrA and parC conferring multidrug resistance successfully in the clinical setting. The aim of this study was (1) to investigate the relationship of specific …

verfasst von:
Jose-Manuel Rodríguez-Martínez, Lorena Lopez-Cerero, Ana García-Duque, Jesus Rodriguez-Baño, Alvaro Pascual

Open Access 17.11.2021 | Review

The role of potentiating mutations in the evolution of pandemic Escherichia coli clones

The Escherichia coli species exhibits a vast array of variable lifestyles, including environmental, commensal, and pathogenic organisms. Many of these E. coli contribute significantly to the global threat of antimicrobial resistance (AMR).

verfasst von:
Elizabeth A. Cummins, Ann E. Snaith, Alan McNally, Rebecca J. Hall

15.11.2021 | Original Article

Molecular epidemiology of extended-spectrum beta-lactamase–producing extra-intestinal pathogenic Escherichia coli strains over a 2-year period (2017–2019) from Zimbabwe

This study was designed to characterize extended-spectrum beta-lactamase (ESBL)–producing extra-intestinal pathogenic Escherichia coli (E.coli) (ExPEC) associated with urinary tract infections in nine different geographic regions of Zimbabwe over …

verfasst von:
Faustinos Tatenda Takawira, Johann DD Pitout, Gaetän Thilliez, Tapfumanei Mashe, Ana Victoria Gutierrez, Robert A Kingsley, Gisele Peirano, Jorge Matheu, Stanley M Midzi, Lusubilo W Mwamakamba, David L Gally, Andrew Tarupiwa, Leckson Mukavhi, Marthie M Ehlers, Sekesai Mtapuri-Zinyowera, Marleen M Kock

09.11.2021 | Review

Population-based epidemiology of Escherichia coli ST1193 causing blood stream infections in a centralized Canadian region

Escherichia coli ST1193 is an emerging global clone associated with fluoroquinolone resistance. A population-based study described genomics, clinical factors, susceptibility patterns, and incidence rates of ST1193 (n = 69) causing incident blood …

verfasst von:
Gisele Peirano, Yasufumi Matsumara, Diego Nobrega, Rebekah DeVinney, Johann Pitout

19.07.2021 | Original Article

Global molecular epidemiology of carbapenem-resistant Escherichia coli (2002–2017)

The emergence of carbapenem-resistant (CR) Escherichia coli obliges an assessment of such strains’ molecular epidemiology. Accordingly, we characterized in detail a globally distributed collection of CR E. coli isolates, then explored for …

verfasst von:
Brian D. Johnston, Paul Thuras, Stephen B. Porter, Melissa Anacker, Brittany VonBank, Paula Snippes Vagnone, Medora Witwer, Mariana Castanheira, James R. Johnson

19.05.2021 | Original Article

The importance of Escherichia coli clonal complex 10 and ST131 among Tanzanian patients on antimicrobial resistance surveillance programs

The objective of this study was to characterize antimicrobial resistance (AMR) of WHO priority 1 critical pathogen (extrapathogenic Escherichia coli (ExPEC), sequence types (STs), and ST131 clades from patients in Tanzania so as to guide specific …

verfasst von:
Jeremiah Seni, Gisele Peirano, Stephen E. Mshana, Johann D. D. Pitout, Rebekah DeVinney